Sign in to use this feature.

Years

Between: -

Subjects

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Journals

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Article Types

Countries / Regions

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Search Results (3,356)

Search Parameters:
Keywords = exciting frequency

Order results
Result details
Results per page
Select all
Export citation of selected articles as:
20 pages, 3035 KiB  
Article
Study of Taconis-Based Cryogenic Thermoacoustic Engine with Hydrogen and Helium
by Matthew P. Shenton, Jacob W. Leachman and Konstantin I. Matveev
Energies 2025, 18(15), 4114; https://doi.org/10.3390/en18154114 (registering DOI) - 2 Aug 2025
Abstract
Taconis oscillations represent spontaneous excitation of acoustic modes in tubes with large temperature gradients in cryogenic systems. In this study, Taconis oscillations in hydrogen and helium systems are enhanced with a porous material resulting in a standing-wave thermoacoustic engine. A theoretical model is [...] Read more.
Taconis oscillations represent spontaneous excitation of acoustic modes in tubes with large temperature gradients in cryogenic systems. In this study, Taconis oscillations in hydrogen and helium systems are enhanced with a porous material resulting in a standing-wave thermoacoustic engine. A theoretical model is developed using the thermoacoustic software DeltaEC, version v6.4b2.7, to predict system performance, and an experimental apparatus is constructed for engine characterization. The low-amplitude thermoacoustic model predicts the pressure amplitude, frequency, and temperature gradient required for excitation of the standing-wave system. Experimental measurements, including the onset temperature ratio, acoustic pressure amplitudes, and frequencies, are recorded for different stack materials and geometries. The findings indicate that, independent of stack, hydrogen systems excite at smaller temperature differentials than helium (because of different properties such as lower viscosity for hydrogen), and the stack geometry and material affect the onset temperature ratio. However, pressure amplitude in the excited states varies minimally. Initial measurements are also conducted in a cooling setup with an added regenerator. The configuration with stainless-steel mesh screens produces a small cryogenic refrigeration effect with a decrease in temperature of about 1 K. The reported characterization of a Taconis-based thermoacoustic engine can be useful for the development of novel thermal management systems for cryogenic storage vessels, including refrigeration and pressurization. Full article
(This article belongs to the Section A5: Hydrogen Energy)
Show Figures

Figure 1

25 pages, 7503 KiB  
Article
A Diagnostic Framework for Decoupling Multi-Source Vibrations in Complex Machinery: An Improved OTPA Application on a Combine Harvester Chassis
by Haiyang Wang, Zhong Tang, Liyun Lao, Honglei Zhang, Jiabao Gu and Qi He
Appl. Sci. 2025, 15(15), 8581; https://doi.org/10.3390/app15158581 (registering DOI) - 1 Aug 2025
Abstract
Complex mechanical systems, such as agricultural combine harvesters, are subjected to dynamic excitations from multiple coupled sources, compromising structural integrity and operational reliability. Disentangling these vibrations to identify dominant sources and quantify their transmission paths remains a significant engineering challenge. This study proposes [...] Read more.
Complex mechanical systems, such as agricultural combine harvesters, are subjected to dynamic excitations from multiple coupled sources, compromising structural integrity and operational reliability. Disentangling these vibrations to identify dominant sources and quantify their transmission paths remains a significant engineering challenge. This study proposes a robust diagnostic framework to address this issue. We employed a multi-condition vibration test with sequential source activation and an improved Operational Transfer Path Analysis (OTPA) method. Applied to a harvester chassis, the results revealed that vibration energy is predominantly concentrated in the 0–200 Hz frequency band. Path contribution analysis quantified that the “cutting header → conveyor trough → hydraulic cylinder → chassis frame” path is the most critical contributor to vertical vibration, with a vibration acceleration level of 117.6 dB. Further analysis identified the engine (29.3 Hz) as the primary source for vertical vibration, while lateral vibration was mainly attributed to a coupled resonance between the threshing cylinder (58 Hz) and the engine’s second-order harmonic. This study’s theoretical contribution lies in validating a powerful methodology for vibration source apportionment in complex systems. Practically, the findings provide direct, actionable insights for targeted structural optimization and vibration suppression. Full article
Show Figures

Figure 1

21 pages, 3864 KiB  
Article
Sub-MHz EMAR for Non-Contact Thickness Measurement: How Ultrasonic Wave Directivity Affects Accuracy
by Alexander Siegl, David Auer, Bernhard Schweighofer, Andre Hochfellner, Gerald Klösch and Hannes Wegleiter
Sensors 2025, 25(15), 4746; https://doi.org/10.3390/s25154746 (registering DOI) - 1 Aug 2025
Abstract
Electromagnetic acoustic resonance (EMAR) is a well-established non-contact method for ultrasonic thickness measurement, typically operated at frequencies above 1 MHz using an electromagnetic acoustic transducer (EMAT). This study successfully extends EMAR into the sub-MHz range, allowing supply voltages below 60 V and thus [...] Read more.
Electromagnetic acoustic resonance (EMAR) is a well-established non-contact method for ultrasonic thickness measurement, typically operated at frequencies above 1 MHz using an electromagnetic acoustic transducer (EMAT). This study successfully extends EMAR into the sub-MHz range, allowing supply voltages below 60 V and thus offering safer and more cost-effective operation. Experiments were conducted on copper blocks approximately 20 mm thick, where a relative thickness accuracy of better than 0.2% is obtained. Regarding this result, the research identifies a critical design principle: Stable thickness resonances and subsequently accurate thickness measurement are achieved when the ratio of ultrasonic wavelength to EMAT track width (λ/w) falls below 1. This minimizes the excitation and interactions with structural eigenmodes, ensuring consistent measurement reliability. To support this, the study introduces a system-based model to simulate the EMAR method. The model provides detailed insights into how wave propagation affects the accuracy of EMAR measurements. Experimental results align well with the simulation outcome and confirm the feasibility of EMAR in the sub-MHz regime without compromising precision. These findings highlight the potential of low-voltage EMAR as a safer, cost-effective, and highly accurate approach for industrial ultrasonic thickness measurements. Full article
(This article belongs to the Special Issue Electromagnetic Sensing and Its Applications)
Show Figures

Figure 1

22 pages, 2499 KiB  
Article
Low-Power Vibrothermography for Detecting Barely Visible Impact Damage in CFRP Laminates: A Comparative Imaging Study
by Zulham Hidayat, Muhammet Ebubekir Torbali, Nicolas P. Avdelidis and Henrique Fernandes
Appl. Sci. 2025, 15(15), 8514; https://doi.org/10.3390/app15158514 (registering DOI) - 31 Jul 2025
Viewed by 47
Abstract
This study explores the application of low-power vibrothermography (LVT) for detecting barely visible impact damage (BVID) in carbon fibre-reinforced polymer (CFRP) laminates. Composite specimens with varying impact energies (2.5–20 J) were excited using a single piezoelectric transducer with a nominal centre frequency of [...] Read more.
This study explores the application of low-power vibrothermography (LVT) for detecting barely visible impact damage (BVID) in carbon fibre-reinforced polymer (CFRP) laminates. Composite specimens with varying impact energies (2.5–20 J) were excited using a single piezoelectric transducer with a nominal centre frequency of 28 kHz, operated at a fixed excitation frequency of 28 kHz. Thermal data were captured using an infrared camera. To enhance defect visibility and suppress background noise, the raw thermal sequences were processed using principal component analysis (PCA) and robust principal component analysis (RPCA). In LVT, RPCA and PCA provided comparable signal-to-noise ratios (SNR), with no consistent advantage for either method across all cases. In contrast, for pulsed thermography (PT) data, RPCA consistently resulted in higher SNR values, except for one sample. The LVT results were further validated by comparison with PT and phased array ultrasonic testing (PAUT) data to confirm the location and shape of detected damage. These findings demonstrate that LVT, when combined with PCA or RPCA, offers a reliable method for identifying BVID and can support safer, more efficient structural health monitoring of composite materials. Full article
(This article belongs to the Special Issue Application of Acoustics as a Structural Health Monitoring Technology)
Show Figures

Figure 1

12 pages, 1773 KiB  
Article
Low-Frequency rTMS and Diazepam Exert Synergistic Effects on the Excitability of an SH-SY5Y Model of Epileptiform Activity
by Ioannis Dardalas, Efstratios K. Kosmidis, Roza Lagoudaki, Vasilios K. Kimiskidis, Theodoros Samaras, Theodoros Moysiadis, Dimitrios Kouvelas and Chryssa Pourzitaki
Biomedicines 2025, 13(8), 1857; https://doi.org/10.3390/biomedicines13081857 - 30 Jul 2025
Viewed by 209
Abstract
Background/Objectives: Epilepsy is a brain condition that affects millions of people worldwide. Although there are many antiepileptic drugs with different mechanisms of action, many patients still fail to control their agonizing symptoms, a situation that highlights the need for more strategies to address [...] Read more.
Background/Objectives: Epilepsy is a brain condition that affects millions of people worldwide. Although there are many antiepileptic drugs with different mechanisms of action, many patients still fail to control their agonizing symptoms, a situation that highlights the need for more strategies to address this issue. In this in vitro study, we elucidated and characterized the alterations in intracellular Ca2+ levels in cell cultures where diazepam and repetitive transcranial magnetic stimulation were implemented, alone or in combination. Methods: Using the differentiated human-derived neuroblastoma cell line SH-SY5Y, we measured the alterations in intracellular Ca2+ levels under the impact of either low-frequency repetitive transcranial magnetic stimulation (1 Hz), diazepam (14 μM), or their combination. We used the Ca2+-sensitive fluorescent indicator Fluo-4 acetoxymethyl ester for calcium imaging, while neuronal excitation was achieved with 50 mM KCl. Results: The highest median fluorescence intensity increase (%ΔF/F = 24.80) was observed in control cell cultures, followed by rTMS cultures (%ΔF/F = 16.96) and diazepam cultures (%ΔF/F = 11.46). The lowest median fluorescence intensity value (%ΔF/F =−0.44) was observed when diazepam was used concomitantly with repetitive transcranial magnetic stimulation. Post hoc analysis assessed pairwise differences, showing statistically significant differentiation between the control group and all other groups. Additionally, statistically significant results were observed between repetitive transcranial magnetic stimulation or diazepam and their combination, but not between them. Conclusions: The combination of diazepam and repetitive transcranial magnetic stimulation resulted in the most significant reduction in intracellular Ca2+ levels, as indicated by the lowest fluorescence values compared with the control group. Individually, each treatment produced a notable but less pronounced effect. We conclude that both diazepam and low-frequency repetitive transcranial magnetic stimulation can control epileptiform activity in vitro, while their combination is the most effective treatment. Full article
(This article belongs to the Special Issue Epilepsy: From Mechanisms to Therapeutic Approaches)
Show Figures

Figure 1

20 pages, 17113 KiB  
Article
Seismic Performance of an Asymmetric Tall-Pier Girder Bridge with Fluid Viscous Dampers Under Near-Field Earthquakes
by Ziang Pan, Qiming Qi, Jianxian He, Huaping Yang, Changjiang Shao, Wanting Gong and Haomeng Cui
Symmetry 2025, 17(8), 1209; https://doi.org/10.3390/sym17081209 - 30 Jul 2025
Viewed by 145
Abstract
Tall-pier girder bridges with fluid viscous dampers (FVDs) are widely used in earthquake-prone mountainous areas. However, the influence of higher-order modes and near-field earthquakes on tall piers has rarely been studied. Based on an asymmetric tall-pier girder bridge, a finite element model is [...] Read more.
Tall-pier girder bridges with fluid viscous dampers (FVDs) are widely used in earthquake-prone mountainous areas. However, the influence of higher-order modes and near-field earthquakes on tall piers has rarely been studied. Based on an asymmetric tall-pier girder bridge, a finite element model is established, and the parameters of FVDs are optimized using SAP2000. The higher-order mode effects on tall piers are explored by proportionally reducing the pier heights. The pulse effects of near-field earthquakes on FVD mitigation and higher-order modes are analyzed. The optimal FVDs can coordinate the force distribution among tall piers, effectively reducing displacement responses and internal forces. Due to higher-order modes, the internal force envelopes of tall piers exhibit concave-convex distributions. As pier heights decrease, the internal force envelopes gradually become linear, implying reduced higher-order mode effects. Long-period pulse-like motions produce the maximum seismic responses because the slender tall-pier bridge is sensitive to high spectral accelerations in medium-to-long periods. The higher-order modes are more easily excited by near-field motions with large spectral values in the high-frequency range. Overall, FVDs can simultaneously reduce the seismic responses of tall piers and diminish the influence of higher-order modes. Full article
(This article belongs to the Section Engineering and Materials)
Show Figures

Figure 1

17 pages, 2616 KiB  
Article
Investigation of the Dynamic Characterization of Traditional and Modern Building Materials Using an Impact Excitation Test
by Anil Ozdemir
Buildings 2025, 15(15), 2682; https://doi.org/10.3390/buildings15152682 - 30 Jul 2025
Viewed by 168
Abstract
This study presents a comprehensive non-destructive evaluation of a broad range of construction materials using the impulse excitation of vibration (IEV) technique. Tested specimens included low- and normal-strength concrete, fiber-reinforced concrete (with basalt, polypropylene, and glass fibers), lime mortars (NHL-2 and -3.5), plaster, [...] Read more.
This study presents a comprehensive non-destructive evaluation of a broad range of construction materials using the impulse excitation of vibration (IEV) technique. Tested specimens included low- and normal-strength concrete, fiber-reinforced concrete (with basalt, polypropylene, and glass fibers), lime mortars (NHL-2 and -3.5), plaster, and clay bricks (light and dark). Compressive and flexural strength tests complemented dynamic resonance testing on the same samples to ensure full mechanical characterization. Flexural and torsional resonance frequencies were used to calculate dynamic elastic modulus, shear modulus, and Poisson’s ratio. Strong correlations were observed between dynamic elastic modulus and shear modulus, supporting the compatibility of dynamic results with the classical elasticity theory. Flexural frequencies were more sensitive to material differences than torsional ones. Fiber additives, particularly basalt and polypropylene, significantly improved dynamic stiffness, increasing the dynamic elastic modulus/compressive strength ratio by up to 23%. In contrast, normal-strength concrete exhibited limited stiffness improvement despite higher strength. These findings highlight the reliability of IEV in mechanical properties across diverse material types and provide comparative reference data for concrete and masonry applications. Full article
(This article belongs to the Special Issue Advanced Studies in Structure Materials—2nd Edition)
Show Figures

Figure 1

20 pages, 4256 KiB  
Article
Design Strategies for Stack-Based Piezoelectric Energy Harvesters near Bridge Bearings
by Philipp Mattauch, Oliver Schneider and Gerhard Fischerauer
Sensors 2025, 25(15), 4692; https://doi.org/10.3390/s25154692 - 29 Jul 2025
Viewed by 128
Abstract
Energy harvesting systems (EHSs) are widely used to power wireless sensors. Piezoelectric harvesters have the advantage of producing an electric signal directly related to the exciting force and can thus be used to power condition monitoring sensors in dynamically loaded structures such as [...] Read more.
Energy harvesting systems (EHSs) are widely used to power wireless sensors. Piezoelectric harvesters have the advantage of producing an electric signal directly related to the exciting force and can thus be used to power condition monitoring sensors in dynamically loaded structures such as bridges. The need for such monitoring is exemplified by the fact that the condition of close to 25% of public roadway bridges in, e.g., Germany is not satisfactory. Stack-based piezoelectric energy harvesting systems (pEHSs) installed near bridge bearings could provide information about the traffic and dynamic loads on the one hand and condition-dependent changes in the bridge characteristics on the other. This paper presents an approach to co-optimizing the design of the mechanical and electrical components using a nonlinear solver. Such an approach has not been described in the open literature to the best of the authors’ knowledge. The mechanical excitation is estimated through a finite element simulation, and the electric circuitry is modeled in Simulink to account for the nonlinear characteristics of rectifying diodes. We use real traffic data to create statistical randomized scenarios for the optimization and statistical variation. A main result of this work is that it reveals the strong dependence of the energy output on the interaction between bridge, harvester, and traffic details. A second result is that the methodology yields design criteria for the harvester such that the energy output is maximized. Through the case study of an actual middle-sized bridge in Germany, we demonstrate the feasibility of harvesting a time-averaged power of several milliwatts throughout the day. Comparing the total amount of harvested energy for 1000 randomized traffic scenarios, we demonstrate the suitability of pEHS to power wireless sensor nodes. In addition, we show the potential sensory usability for traffic observation (vehicle frequency, vehicle weight, axle load, etc.). Full article
(This article belongs to the Special Issue Energy Harvesting Technologies for Wireless Sensors)
Show Figures

Figure 1

9 pages, 2434 KiB  
Article
Locally Generated Whistler-Mode Waves Before Dipolarization Fronts
by Boning Zhao, Chengming Liu, Jinbin Cao, Yangyang Liu and Xining Xing
Universe 2025, 11(8), 249; https://doi.org/10.3390/universe11080249 - 29 Jul 2025
Viewed by 145
Abstract
Whistler-mode waves, electromagnetic emissions with frequencies between the lower hybrid and electron cyclotron frequencies, are ubiquitous in planetary magnetotails. They are known to play a vital role in electron scattering and acceleration, originating primarily within strong magnetic field regions behind dipolarization fronts (DFs). [...] Read more.
Whistler-mode waves, electromagnetic emissions with frequencies between the lower hybrid and electron cyclotron frequencies, are ubiquitous in planetary magnetotails. They are known to play a vital role in electron scattering and acceleration, originating primarily within strong magnetic field regions behind dipolarization fronts (DFs). In contrast to this established knowledge, we present a comprehensive analysis of whistler-mode waves generated locally within weak magnetic field regions ahead of DFs, utilizing high-cadence measurements from the MMS mission. By resolving the wave dispersion relations, we demonstrate that these emissions arise from cyclotron resonance with local electrons exhibiting weak perpendicular temperature anisotropy (Ae < 1.2). We further propose that this anisotropy may develop due to magnetic mirror structures forming upstream of DFs. Our findings challenge the conventional view that whistler-mode generation requires strong magnetic fields near DFs, providing new insights into understanding wave excitation mechanisms in planetary magnetotails. Full article
(This article belongs to the Special Issue Universe: Feature Papers 2025—Space Science)
Show Figures

Figure 1

20 pages, 3716 KiB  
Article
Modeling and Validation of a Spring-Coupled Two-Pendulum System Under Large Free Nonlinear Oscillations
by Borislav Ganev, Marin B. Marinov, Ivan Kralov and Anastas Ivanov
Machines 2025, 13(8), 660; https://doi.org/10.3390/machines13080660 - 28 Jul 2025
Viewed by 155
Abstract
Studying nonlinear oscillations in mechanical systems is fundamental to understanding complex dynamic behavior in engineering applications. While classical analytical methods remain valuable for systems with limited complexity, they become increasingly inadequate when nonlinearities are strong and geometrically induced, as in the case of [...] Read more.
Studying nonlinear oscillations in mechanical systems is fundamental to understanding complex dynamic behavior in engineering applications. While classical analytical methods remain valuable for systems with limited complexity, they become increasingly inadequate when nonlinearities are strong and geometrically induced, as in the case of large-amplitude oscillations. This paper presents a combined numerical and experimental investigation of a mechanical system composed of two coupled pendulums, exhibiting significant nonlinear behavior due to elastic deformation throughout their motion. A mathematical model of the system was developed using the MatLab/Simulink ver.6.1 environment, considering gravitational, inertial, and nonlinear elastic restoring forces. One of the major challenges in accurately modeling such systems is accurately representing damping, particularly in the absence of dedicated dampers. In this work, damping coefficients were experimentally identified through decrement measurements and incorporated into the simulation model to improve predictive accuracy. The simulation outputs, including angular displacements, velocities, accelerations, and phase trajectories over time, were validated against experimental results obtained via high-precision inertial sensors. The comparison shows a strong correlation between numerical and experimental data, with minimal relative errors in amplitude and frequency. This research represents the first stage of a broader study aimed at analyzing forced and parametrically excited oscillations. Beyond validating the model, the study contributes to the design of a robust experimental framework suitable for further exploration of nonlinear dynamics. The findings have practical implications for the development and control of mechanical systems subject to dynamic loads, with potential applications in automation, vibration analysis, and system diagnostics. Full article
(This article belongs to the Section Machine Design and Theory)
Show Figures

Figure 1

17 pages, 6326 KiB  
Article
Dynamic Stress Wave Response of Thin-Walled Circular Cylindrical Shell Under Thermal Effects and Axial Harmonic Compression Boundary Condition
by Desejo Filipeson Sozinando, Patrick Nziu, Bernard Xavier Tchomeni and Alfayo Anyika Alugongo
Appl. Mech. 2025, 6(3), 55; https://doi.org/10.3390/applmech6030055 - 28 Jul 2025
Viewed by 302
Abstract
The interaction between thermal fields and mechanical loads in thin-walled cylindrical shells introduces complex dynamic behaviors relevant to aerospace and mechanical engineering applications. This study investigates the axial stress wave propagation in a circular cylindrical shell subjected to combined thermal gradients and time-dependent [...] Read more.
The interaction between thermal fields and mechanical loads in thin-walled cylindrical shells introduces complex dynamic behaviors relevant to aerospace and mechanical engineering applications. This study investigates the axial stress wave propagation in a circular cylindrical shell subjected to combined thermal gradients and time-dependent harmonic compression. A semi-analytical model based on Donnell–Mushtari–Vlasov (DMV) shells theory is developed to derive the governing equations, incorporating elastic, inertial, and thermal expansion effects. Modal solutions are obtained to evaluate displacement and stress distributions across varying thermal and mechanical excitation conditions. Empirical Mode Decomposition (EMD) and Instantaneous Frequency (IF) analysis are employed to extract time–frequency characteristics of the dynamic response. Complementary Finite Element Analysis (FEA) is conducted to assess modal deformations, stress wave amplification, and the influence of thermal softening on resonance frequencies. Results reveal that increasing thermal gradients leads to significant reductions in natural frequencies and amplifies stress responses at critical excitation frequencies. The combination of analytical and numerical approaches captures the coupled thermomechanical effects on shell dynamics, providing an understanding of resonance amplification, modal energy distribution, and thermal-induced stiffness variation under axial harmonic excitation across thin-walled cylindrical structures. Full article
Show Figures

Figure 1

17 pages, 4394 KiB  
Article
Nonclinical Human Cardiac New Approach Methodologies (NAMs) Predict Vanoxerine-Induced Proarrhythmic Potential
by M. Iveth Garcia, Bhavya Bhardwaj, Keri Dame, Verena Charwat, Brian A. Siemons, Ishan Goswami, Omnia A. Ismaiel, Sabyasachy Mistry, Tromondae K. Feaster, Kevin E. Healy, Alexandre J. S. Ribeiro and Ksenia Blinova
J. Cardiovasc. Dev. Dis. 2025, 12(8), 285; https://doi.org/10.3390/jcdd12080285 - 26 Jul 2025
Viewed by 345
Abstract
New approach methodologies (NAMs), including microphysiological systems (MPSs), can recapitulate structural and functional complexities of organs. Vanoxerine was reported to induce cardiac adverse events, including torsade de points (TdP), in a Phase III clinical trial. Despite earlier nonclinical animal models and Phase I–II [...] Read more.
New approach methodologies (NAMs), including microphysiological systems (MPSs), can recapitulate structural and functional complexities of organs. Vanoxerine was reported to induce cardiac adverse events, including torsade de points (TdP), in a Phase III clinical trial. Despite earlier nonclinical animal models and Phase I–II clinical trials, events of QT prolongation or proarrhythmia were not observed. Here, we utilized cardiac NAMs to evaluate the functional consequences of vanoxerine treatment on human cardiac excitation–contraction coupling. The cardiac MPS used in this study was a microfabricated fluidic culture platform with human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) capable of evaluating voltage, intracellular calcium handling, and contractility. Likewise, the hiPSC-CM comprehensive in vitro proarrhythmia assay (CiPA) was employed based on multielectrode array (MEA). Vanoxerine treatment delayed repolarization in a concentration-dependent manner and induced proarrhythmic events in both NAM platforms. The complex cardiac MPS displayed a frequency-dependent vanoxerine response such that EADs were eliminated at a faster pacing rate (1.5 Hz). Moreover, exposure analysis revealed a 99% vanoxerine loss in the cardiac MPS. TdP risk analysis demonstrated high to intermediate TdP risk at clinically relevant concentrations of vanoxerine and frequency-independent EAD events in the hiPSC-CM CiPA model. These findings demonstrate that nonclinical cardiac NAMs can recapitulate clinical outcomes, including detection of vanoxerine-induced delayed repolarization and proarrhythmic effects. Moreover, this work provides a foundation to evaluate the safety and efficacy of novel compounds to reduce the dependence on animal studies. Full article
Show Figures

Graphical abstract

17 pages, 2625 KiB  
Article
Monitoring and Diagnostics of Non-Thermal Plasmas in the Food Sector Using Optical Emission Spectroscopy
by Sanda Pleslić and Franko Katalenić
Appl. Sci. 2025, 15(15), 8325; https://doi.org/10.3390/app15158325 - 26 Jul 2025
Viewed by 100
Abstract
Non-thermal plasma technology is used in the food sector due to its many advantages such as low operating costs, fast and efficient processing at low temperatures, minimal environmental impact, and preservation of sensory and nutritional properties. In this article, the plasma was generated [...] Read more.
Non-thermal plasma technology is used in the food sector due to its many advantages such as low operating costs, fast and efficient processing at low temperatures, minimal environmental impact, and preservation of sensory and nutritional properties. In this article, the plasma was generated using a high-voltage electrical discharge (HVED) with argon at a voltage of 35 kV and a frequency of 60 Hz. Plasma monitoring and diagnostics were performed using optical emission spectroscopy (OES) to optimise the process parameters and for quality control. OES was used as a non-invasive sensor to collect useful information about the properties of the plasma and to identify excited species. The values obtained for electron temperature and electron density (up to 2.3 eV and up to 1023 m3) confirmed that the generated plasma is a non-thermal plasma. Therefore, the use of OES is recommended in the daily control of food processing, as this is necessary to confirm that the processes are non-thermal and suitable for the food sector. Full article
(This article belongs to the Special Issue Innovative Technology in Food Analysis and Processing)
Show Figures

Figure 1

20 pages, 7725 KiB  
Article
Harmonic Distortion Peculiarities of High-Frequency SiGe HBT Power Cells for Radar Front End and Wireless Communication
by Paulius Sakalas and Anindya Mukherjee
Electronics 2025, 14(15), 2984; https://doi.org/10.3390/electronics14152984 - 26 Jul 2025
Viewed by 223
Abstract
High-frequency (h. f.) harmonic distortion (HD) of advanced SiGe heterojunction bipolar transistor (HBT)-based power cells (PwCs), featuring optimized metallization interconnections between individual HBTs, was investigated. Single tone input power (Pin) excitations at 1, 2, 5, and 10 GHz frequencies were [...] Read more.
High-frequency (h. f.) harmonic distortion (HD) of advanced SiGe heterojunction bipolar transistor (HBT)-based power cells (PwCs), featuring optimized metallization interconnections between individual HBTs, was investigated. Single tone input power (Pin) excitations at 1, 2, 5, and 10 GHz frequencies were employed. The output power (Pout) of the fundamental tone and its harmonics were analyzed in both the frequency and time domains. A rapid increase in the third harmonic of Pout was observed at input powers exceeding −8 dBm for a fundamental frequency of 10 GHz in two different PwC technologies. This increase in the third harmonic was analyzed in terms of nonlinear current waveforms, the nonlinearity of the HBT p-n junction diffusion capacitances, substrate current behavior versus Pin, and avalanche multiplication current. To assess the RF power performance of the PwCs, scalar and vectorial load-pull (LP) measurements were conducted and analyzed. Under matched conditions, the SiGe PwCs demonstrated good linearity, particularly at high frequencies. The key power performance of the PwCs was measured and simulated as follows: input power 1 dB compression point (Pin_1dB) of −3 dBm, transducer power gain (GT) of 15 dB, and power added efficiency (PAE) of 50% at 30 GHz. All measured data were corroborated with simulations using the compact model HiCuM L2. Full article
Show Figures

Figure 1

24 pages, 4281 KiB  
Article
Free Vibration Characteristics of FG-CNTRC Conical–Cylindrical Combined Shells Resting on Elastic Foundations Using the Haar Wavelet Discretization Method
by Jianyu Fan, Haoran Zhang, Yongqiang Tu, Shaohui Yang, Yan Huang, Zhichang Du and Hakim Boudaoud
Polymers 2025, 17(15), 2035; https://doi.org/10.3390/polym17152035 - 25 Jul 2025
Viewed by 193
Abstract
Functionally graded carbon nanotube reinforced composites (FG-CNTRCs) are a novel breed of polymer nanocomposite, in which the nonuniform distribution of the carbon nanotube (CNT) reinforcement is adopted to maximize the macro-mechanical performance of the polymer with a lower content of CNTs. Composite conical–cylindrical [...] Read more.
Functionally graded carbon nanotube reinforced composites (FG-CNTRCs) are a novel breed of polymer nanocomposite, in which the nonuniform distribution of the carbon nanotube (CNT) reinforcement is adopted to maximize the macro-mechanical performance of the polymer with a lower content of CNTs. Composite conical–cylindrical combined shells (CCCSs) are widely utilized as loading-bearing components in various engineering applications, and a comprehensive understanding of the vibration characteristics of these shells under different external excitations and boundary conditions is crucial for engineering applications. In this study, the free vibration behaviors of FG-CNTRC CCCSs supported by an elastic foundation are examined using the Haar wavelet discretization method (HWDM). First, by means of the HWDM, the equations of motion of each shell segment, the continuity and boundary conditions are converted into a system of algebraic equations. Subsequently, the natural frequencies and modes of the CCCSs are achieved by calculating the resultant algebraic equations. The convergence and accuracy are evaluated, and the results demonstrate that the proposed method has stable convergence, high efficiency, and excellent accuracy. Furthermore, an exhaustive parametric investigation is conducted to reveal the effects of foundation stiffnesses, boundary conditions, material mechanical properties, and geometric parameters on the vibration characteristics of the FG-CNTRC CCCS. Full article
Show Figures

Figure 1

Back to TopTop