Search Results (3,671)

The prevalent endocrine disruptor bisphenol A (BPA) is associated with aging-related conditions, including metabolic disorders. It has been shown that BPA promotes bone fragility through oxidative stress-induced apoptosis and impaired osteoblast differentiation. The identification of sustainable bioactive substances that alleviate BPA-induced bone toxicity is thus of biomedical and environmental significance. Wolffia globosa (WG), the world’s smallest flowering aquatic plant, has recently gained attention as a high-protein, antioxidant-rich nutraceutical, yet its impact on BPA-induced osteoblast dysfunction has not been systematically investigated. This study presents a comprehensive assessment of WG ethanolic extract (WGE) in MC3T3-E1 pre-osteoblasts, incorporating thorough phytochemical characterization, acute high-dose and chronic low-dose BPA exposure models, and multi-faceted mechanistic analysis. LC-MS/MS profiling identified luteolin (116.17 ± 0.69 µg/g), rosmarinic acid (54.80 ± 2.12 µg/g), and apigenin (48.77 ± 0.61 µg/g) as the predominant bioactive compounds. WGE exhibited potent antioxidant capacity across DPPH and ABTS radical scavenging assays, complemented by high ORAC and FRAP values, reflecting broad-spectrum antioxidant mechanisms. Treatment with WGE (25 and 50 µg/mL) resulted in significant alleviation of BPA-induced cytotoxicity, decreased intracellular ROS levels, and inhibited apoptosis. WGE (12.5 µg/mL) also modulated autophagy-related markers (LC3-II, Beclin-1, and p62), suggesting potential autophagic participation, although flux verification was not conducted. Treatment with WGE (12.5 µg/mL) also restored BPA-suppressed osteogenesis under chronic exposure, as evidenced by enhanced alkaline phosphatase activity, and increased both mineralization and upregulation of osteogenic genes including runt-related transcription factor2 (Runx2), collagen type I alpha 1 (Colla1), alkaline phosphatase (ALP), and osteocalcin (OCN). These effects were accompanied by partial reactivation of Wnt/β-catenin signaling. This study is the first to demonstrate that WGE protects osteoblasts from BPA toxicity by concurrently strengthening antioxidant defenses, limiting apoptosis, modulating autophagy-related markers, and supporting β-catenin-mediated osteogenesis, highlighting WG as a promising sustainable nutraceutical candidate for the prevention of environmental toxin-related bone fragility. Full article

Understanding trade-offs and synergies among ecosystem services (ESs) along environmental gradients is crucial for sustainable oasis management. This study investigated four key ESs—carbon storage (CS), habitat quality (HQ), water yield (WY), and soil conservation (SC)—in three typical oases along water–heat gradients in arid northwestern China. The InVEST model was used to quantify ESs in 1990, 2005, and 2022, and Pearson correlation, geographically weighted regression, K-means clustering, and random forest models were applied to analyze service relationships, ecosystem service bundles (ESBs), and driving factors. The results showed that CS and HQ maintained strong synergies, while the WY–SC relationship shifted from weak trade-offs under drier conditions to stronger synergies under more favorable water–heat conditions. Geographically weighted regression revealed spatial heterogeneity and directional asymmetry in ES relationships. Four ESB types were identified: ecologically fragile zones, ecological transition or buffer zones, agricultural production zones, and core ecological source zones. Driving-factor analysis indicated that vegetation-related services were mainly associated with land-cover structure and vegetation growth, whereas hydrological and erosion-related services were more closely linked to precipitation, potential evapotranspiration, temperature, and topography. These findings support differentiated oasis management through ecological restoration, development regulation, water-saving agriculture, and strict ecological protection. Full article

The climate crisis, housing precarity, and the loss of everyday architectural heritage are converging challenges in Mediterranean cities. This article investigates the adaptive reuse of early twentieth-century adobe refugee dwellings in Nea Ionia and Kaisariani, neighborhoods of Attica, Greece, as an integrated social, environmental, and cultural strategy. Historical documentation, urban-morphological analysis, field observations, building survey data, material assessment, and design-based microclimatic analysis were combined to evaluate compatible restoration and bioclimatic upgrades as alternatives to demolition and conventional energy retrofit practices, with the main aim of preserving an important part of Greek history and architecture. The study develops a replicable qualitative assessment framework that identifies how existing adobe envelopes, compact layouts, courtyards, thresholds, vegetated pergolas, and low-water evaporative cooling may support low-carbon housing reuse. The results clarify the current preservation conditions and reuse potential of the selected case-study fragments, showing that adobe dwellings can preserve embodied material value, retain thermal mass and hygroscopic regulation, and support social housing when repaired with compatible, low-impact techniques. The article argues that the reuse of adobe refugee dwellings can function as a distributed urban strategy for housing provision, heritage continuity, and microclimatic adaptation. Its main contribution is a transferable analytical framework for assessing overlooked earthen housing stocks in dense Mediterranean contexts. The study argues that adaptive reuse can serve simultaneously as a means of social housing, a mechanism for optimizing the microclimate, and a means of preserving the tangible and intangible heritage of Greek adobe buildings that have been standing for over 100 years. This position extends circular construction debates by prioritizing non-demolition and direct reuse while preserving an important period of history. Full article

Type 1 Diabetes (T1D) is a complex autoimmune disorder characterized by immune-mediated destruction of pancreatic β cells, driven by genetic susceptibility and modulated by environmental factors, notably the gut microbiome. Dysbiosis, manifested as reduced microbial diversity, perturbations in the Firmicutes/Bacteroidetes ratio, and compromised short-chain fatty acid production, contributes to T1D pathogenesis through mechanisms involving immune system dysregulation and heightened intestinal permeability. Emerging evidence indicates a relationship between the gut and oral microbiomes, as well as the potential influence of the virome and mycobiome. This narrative review synthesizes the current literature on the intricate interplay between the gut microbial ecosystem, the host immune response, and the development of T1D, highlighting the potential for targeted microbiome-based interventions to ameliorate disease progression. A more nuanced understanding of these multi-kingdom interactions is essential for developing precise therapeutic strategies to prevent or delay T1D onset and to improve patient outcomes through restoration of immune tolerance and gut homeostasis. Full article

This paper focuses on the increasing relevance of rewilding in the context of the global ecological crisis. This crisis is conceived not only as a loss of biodiversity, but also as a breakdown in our capacity to dwell meaningfully on Earth. Although rewilding has been developed primarily as an ecological restoration strategy, this paper argues that it is first and foremost an ethical concept. In this sense, starting from Næss’s ecosophy, contemporary theories of self-rewilding, and environmental virtue ethics, this paper develops a philosophical framework that interprets rewilding as a form of dwelling based on the concept of oikos (home). It shows that rewilding entails a transformation of human agency through identification and self-realization, which makes the “ecological self” emerge. As for its methodology, the paper adopts a conceptual and interdisciplinary approach, combining ecology, environmental philosophy, and virtue ethics. The paper concludes that the concept of rewilding should be linked both to ecological restoration and ethical flourishing, requiring the development of certain virtues—e.g., humility and the recognition of ecological dependence. In this regard, rewilding should offer a relevant context to rethink our relationship with nature, starting from the idea of dwelling in the common home. Full article

Landscape Ecological Risk (LER) reflects the potential adverse effects of landscape change on ecological structure, function, and stability. In rapidly urbanizing megacities such as Dhaka, vegetation loss and built-up expansion have intensified environmental pressure over recent decades. This study examines the spatiotemporal dynamics of LER in Dhaka from 2004 to 2024 under the combined influence of vegetation change and urban expansion. Multi-temporal remote sensing data were used to generate land cover maps, derive Fractional Vegetation Cover (FVC), and quantify urbanization intensity using Nighttime Light (NTL) data. The Landscape Ecological Risk Index (LERI) was calculated using landscape pattern metrics, while bivariate spatial autocorrelation and geographically weighted regression (GWR) were applied to examine spatial associations and local spatial heterogeneity. The results show that vegetation degradation affected 34.39% of the study area during 2004–2024, while high-risk zones increased from 24.36% in 2004 to 42.95% in 2024. Land cover analysis further indicates a substantial expansion of built-up areas, accompanied by the contraction and fragmentation of vegetation, agricultural land, and lowland classes. Spatial analyses reveal that the relationships among vegetation cover, urbanization intensity, and ecological risk vary across the city and became increasingly spatially differentiated over time. These findings suggest that vegetation loss and urban expansion are spatially associated with increasing ecological risk in Dhaka. However, the results should be interpreted with caution because of uncertainties related to remotely sensed data, unsupervised land cover classification, resampling procedures, and limited ground validation. Despite these limitations, the study provides a spatially explicit framework for understanding ecological risk dynamics and offers useful evidence for green-space conservation, ecological restoration, and sustainable urban planning in rapidly urbanizing regions. Full article

River ecological restoration in lowland plain basins is often constrained by fragmented river networks, degraded riparian zones, eutrophication risk, and intensive human disturbance. Conventional monitoring approaches rarely connect watershed-scale dynamics with responses from typical restoration units, limiting quantitative evaluation and the separation of direct project outcomes from broader environmental variability. To address this gap, this study developed a collaborative satellite–unmanned aerial vehicle (UAV)–unmanned surface vehicle (USV) monitoring framework and applied it to the Nihe River Basin, China, a lowland plain river undergoing systematic restoration under the Shan-shui Initiative. The framework combines Sentinel-2 time-series imagery, high-resolution Gaofen-1, Gaofen-2, and Jilin-1 imagery, UAV orthophotos, USV observations, and auxiliary environmental datasets. Unlike single-scale monitoring approaches, it links watershed-scale indicators, including water-body dynamics, chlorophyll-related eutrophication risk, riparian ecological background, and soil-water conservation capacity, with unit-scale diagnosis of riparian buffer and riverine wetland restoration. Results showed that river water-body area increased from 37.78 km² to 40.59 km² during 2021–2024, while normalized difference chlorophyll index (NDCI)-based eutrophication risk improved in 9.12% of the monitored river area and degraded in only 0.47%. Riparian vegetation cover remained high, whereas regional soil-water conservation capacity declined due to climatic factors, revealing asynchronous responses between local recovery and regional background conditions. At the unit scale, riparian buffer restoration enhanced buffer continuity and near-bank water quality, as reflected by decreased chemical oxygen demand (COD), increased dissolved oxygen (DO), and limited ammonia nitrogen (NH₃-N) improvement. Riverine wetland restoration promoted land-use adjustment and ecological spatial reorganization. This cross-scale evidence chain supports adaptive management of inland river and wetland restoration projects. Full article

The gut microbiota of fish plays a crucial role in nutrition, metabolism and immune regulation, and is highly sensitive to environmental stressors such as pesticide exposure. This study investigated the effects of emamectin benzoate (EMB) exposure on Asian stinging catfish (Heteropneustes fossilis) gut microbiota using an integrated culture-dependent and culture-independent approach to assess functional and taxonomic dysbiosis. Gut smear samples from control and EMB-treated fish at two sublethal concentrations (0.5 µg/L and 5 µg/L) were analyzed for major functional bacterial groups, including heterotrophic, lipid-hydrolysing, starch-hydrolysing, spore-forming, and Gram-negative bacteria and Pseudomonas spp., using standard plate count techniques. In parallel, microbial community composition and diversity were examined through 16S rRNA (V3–V4 region) gene amplicon sequencing followed by bioinformatic analysis. Culture-based results showed a significant decline in total heterotrophic bacteria and key functional groups in EMB-treated fish, indicating suppression of microbial metabolic activity and functional imbalance. Lipid-hydrolysing and starch-hydrolysing bacteria showed pronounced sensitivity to pesticide exposure, while spore-forming bacteria exhibited a marked reduction, suggesting compromised microbial resilience. Although Gram-negative bacteria declined overall, Pseudomonas spp. displayed a non-linear response, with an initial decrease, followed by partial recovery under higher exposure. Culture-independent analysis demonstrated reduced alpha diversity, altered community structure, and taxonomic shifts in EMB-treated fish. Pseudomonadota exhibited a distinct pattern characterized by decline at 0.5 µg/L and partial recovery at 5 µg/L, reflecting adaptive tolerance rather than restoration of microbial homeostasis. Overall, the combined evidence indicates pronounced EMB-induced gut dysbiosis at both functional and compositional levels. This study highlights the fish gut microbiome as a sensitive biomarker of stress and underscores the ecological risks associated with EMB in aquatic environments. Full article

Anthropogenic disturbances and climate warming threaten the rare paleoendemic species Tetracentron sinense. To identify the divers of its latitudinal adaptation, we integrated functional trait differentiation, environmental filtering, and phylogenetic conservatism. We measured 35 functional traits (leaf morphology, nutrient stoichiometry, stomatal traits, whole-plant architecture) across four natural populations spanning the species’ latitudinal range: BMXS (Baima Snow Mountain), DFD (Dafengding), FP (Foping), LGS (Leigong Mountain). Using correlation analysis, principal component analysis, and phylogenetic community metrics, we found that T. sinense dominated all communities. Populations exhibited divergent strategies: DFD expanded leaf area for light capture under high rainfall and shaded conditions; FP increased height and crown width to compete for light; LGS enhanced nutrient-use efficiency under phosphorus limitation; BMXS promoted phosphorus uptake under nitrogen limitation (N/P < 14). Trait variation correlated significantly with elevation, solar radiation, and temperature. PCA explained 90.44% of total variance, and standardized effect size (SES) values for phylogenetic signals range from −2.031 to 1.973; Phylogenetic signals were stronger in co-occurring taxa than in T. sinense. T. sinense populations in BMXS and FP are structured by competitive exclusion, while those in LGS and DFD by habitat filtering. We conclude that T. sinense achieves latitudinal adaptation by overcoming phylogenetic niche conservatism through phenotypic plasticity. While leaf economic traits remain evolutionarily conserved and niches in glacial refugium are relatively stable, populations adjust trait syndromes via metabolic shifts and structural trade-offs in response to heterogeneous environmental filters. Identifying these adaptive strategies can guide seed sourcing for restoration efforts under climate change. Full article

Across semi-arid and environmentally vulnerable regions, intensifying climate pressures, land degradation, and resource scarcity are placing growing demands on institutions, communities, and land users. However, the knowledge and technical skills required to respond effectively remain uneven and often poorly aligned with local needs. This study presents a comparative skills audit in Kimberley, Upington, and Rietfontein in the Northern Cape, identifying capacity gaps, stakeholder-specific training priorities, and structural barriers in natural resource and sustainable land management. Using questionnaires, semi-structured interviews, participatory site visits, and multi-stakeholder consultations, competencies were assessed across GIS and remote sensing, climate resilience, soil and land restoration, water conservation, sustainable agriculture, and policy literacy. Results show significant disparities in skills proficiency. GIS and remote sensing (0.8) and climate resilience strategies (1.0) were weakest, while policy literacy (1.5) and soil management (2.0) were also limited. Sustainable agriculture (4.0) and water conservation (2.8) showed relatively stronger capacity. Training needs varied by stakeholder, with government prioritizing geospatial tools and governance, and farmers emphasizing climate adaptation and resource management. Key barriers include limited digital infrastructure (83%), insufficient government support (80%), high training costs (78%), and contextual mismatches (50%). Integrated, place-based capacity development is essential to strengthen adaptive governance and long-term resilience. Full article

Intermediate crops, such as Brassica carinata and Camelina sativa, offer a promising pathway for expanding sustainable feedstock supply for advanced biofuels in Europe without competing with food and feed production. This study applies a competitive priority framework to assess the performance of intermediate crops in Italy and Spain, integrating agronomic, environmental, and regulatory dimensions. Using Member State-specific agroecological conditions, cost structures, and land-use profiles, the analysis identifies key challenges across land use and biomass-production stages and links them to measurable indicators and targeted optimisation strategies. Evidence from both experimental studies and modelling indicates that camelina can be seamlessly integrated into existing cropping systems without compromising crop yields or triggering soil carbon losses. These findings highlight the potential of intermediate crops to enhance soil health, to reduce erosion, and to stabilise yields under climate variability. This study also examines the policy conditions required to enable deployment, emphasising the need for region-specific crop calendars, digital traceability systems, and coherent implementation of RED III, CAP, ESCA, and CRCF frameworks. The distinction between volumetric and GHG-based targets is shown to be critical: intermediate crops perform strongly under GHG-based intensity reduction frameworks that reward soil carbon gains and sustainable cultivation. National instruments in Italy and Spain—including the Piano Strategico della PAC, Decreto Biocarburanti, Plan Estratégico de la PAC, and Real Decreto 376/2022—provide mechanisms for operationalising these strategies. Overall, the results demonstrate that intermediate crops can contribute meaningfully to both national and EU renewable energy, soil restoration, and climate mitigation objectives when supported by coherent agronomic and policy frameworks. Full article

Nano-/microplastics (NMPs) accumulation in agricultural soils has become a growing environmental concern due to its negative impacts on soil health, crop productivity, and food safety. Biochar has gained considerable attention as a sustainable soil amendment capable of improving soil quality and mitigating emerging pollutants. This review examines the role of biochar and modified biochar in reducing the mobility, bioavailability, and plant uptake of NMPs through adsorption, aggregation, and immobilization mechanisms. In addition, biochar improves soil fertility by enhancing nutrient retention, water holding capacity, soil structure, and microbial activity, while also contributing to climate change mitigation through carbon sequestration. However, certain biochars may negatively affect saline–alkaline soils because of their high pH and salinity. Generally, biochar application offers multiple environmental benefits, including soil restoration, pollutant mitigation, and enhanced agricultural sustainability. This review synthesizes recent advances in understanding the mechanisms by which biochar influences NMPs behavior in soil–plant systems and highlights current knowledge gaps and future research directions needed to support its effective application in sustainable agriculture. Full article

Mining activities elevate environmental noise and represent a major disturbance in terrestrial ecosystems. Vegetation belts are often used as mitigation measures. This study evaluates the role of Robinia pseudoacacia L. forest plantations in reducing noise at the lignite complex of western Macedonia, in Greece. Field measurements of noise level (LAeq) were conducted inside and outside the plantations from spring to autumn during 2020 and 2021. Measurements were taken at five points across four sites differing in their distance from the noise source. Leaf Area Index (LAI) was recorded, and meteorological variables were measured concurrently. Linear mixed-effect models were used to assess the effects of forest presence, distance from source, climatic conditions, and LAI, while accounting for repeated measurements across sampling days and sites. Noise levels were significantly lower within plantations than outside, indicating that restored forest stands can act as buffers to mining noise. The distance of trees from the noise source and atmospheric conditions are also significant drivers of noise levels. These findings highlight the potential of post-mining plantations to provide an additional acoustic regulation service in restored industrial landscapes. Full article

The massive generation of coal-based solid wastes (CBSWs) poses severe environmental challenges globally, while widespread soil degradation threatens food security and ecosystem stability. This review critically evaluates the technical feasibility and agro-ecological benefits of valorizing CBSWs—including coal gangue, fly ash, gasification slag, and desulfurization gypsum—as soil amendments within a circular economy framework. We systematically examine the physicochemical characteristics of major CBSW types, analyze modification methods that enhance their performance and safety, and assess their multifaceted effects on soil physical structure, chemical properties, nutrient dynamics, heavy metal immobilization, and microbial communities. A dedicated section addresses environmental risks, particularly toxic element leaching, and outlines integrated control strategies from source selection to post-application monitoring. Critical knowledge gaps persist regarding long-term contaminant stability under climate change scenarios, molecular-scale immobilization mechanisms, and economic scalability. Future research must prioritize advanced low-energy modification technologies, robust long-term field studies, and harmonized international regulations. We conclude that with scientifically guided modification and stringent risk management, CBSWs can be transformed into safe, multifunctional soil conditioners, simultaneously addressing industrial waste management and contributing to global restoration of degraded soil health. Full article

Chromium is an environmental pollutant with high toxicity and carcinogenicity. It can induce severe oxidative stress and DNA damage after entering the human body through the food chain. As a plant growth-promoting rhizobacterium (PGPR) with both heavy metal tolerance and plant growth-promoting properties, Klebsiella variicola has considerable potential for the remediation of chromium contamination. In this study, chicory served as the experimental plant to explore the mitigating impacts of K. variicola on stress induced by hexavalent chromium (Cr(VI)) at a concentration of 400 mg/kg. The results showed that chromium severely inhibited the growth of chicory. In contrast, K. variicola significantly reduced the soil chromium content. As the chromium content decreased, the activities of soil urease, sucrase, catalase, and alkaline phosphatase were restored, increasing by 32.60–53.69%. Accordingly, the contents of total phosphorus, available phosphorus, total nitrogen, available nitrogen, soil organic carbon, and available potassium also increased by 34.71–51.81%. In addition, K. variicola reversed the decline in microbial diversity induced by chromium stress, promoted the growth of beneficial bacteria such as Acidobacteriota and Chloroflexota, and enhanced the stability of soil ecosystem functions. Ultimately, the growth inhibition of chicory caused by chromium stress was alleviated, with fresh weight, root length, maximum leaf width, maximum leaf length, plant height, and stem diameter significantly increasing by 21.89–61.60%. This study enhances our comprehension of the various functions of PGPR when exposed to heavy metal stress, and provides support for the development of microbe–plant combined strategies in the remediation of chromium-contaminated soils. Full article