Search Results (94)

Offshore wind turbine operation and maintenance in complex sea states is influenced by the coupled effects of low-frequency vessel drift and high-frequency wave-induced disturbances. In practical operations, the ship dynamic positioning system primarily regulates low-frequency motion through vessel position control, whereas a boarding compensation system is required to attenuate high-frequency six-degrees-of-freedom motions to ensure safe personnel transfer. This study establishes coupled kinematic mapping among the ship dynamic positioning system, the Stewart platform, and a three-degrees-of-freedom gangway and proposes a hierarchical cooperative control architecture. At the upper layer, an extended Kalman filter and an exponential moving average low-pass filter are employed for online state estimation and for separating low-frequency and high-frequency components. A Kalman filter lookahead predictor is then used to generate a short-horizon prediction of the high-frequency component and to construct a feedforward reference signal. At the middle layer, the feedforward reference and the gangway end error feedback are coordinated at the velocity level, and a quadratic programming-based allocation strategy distributes compensation tasks between the Stewart platform and the gangway under safety-related constraints, including actuator stroke limits and singularity avoidance. At the lower layer, a robust feedback controller is designed for the gangway to mitigate modeling uncertainties and environmental disturbances and to ensure stable tracking. MATLAB R2024a-based simulations under representative wave conditions demonstrate that the proposed architecture improves end effector tracking accuracy and closed-loop stability compared with baseline strategies, providing a feasible engineering solution for shipboard boarding operations in complex sea states. Full article

Labor shortages and the need for increased productivity have accelerated the development of robotic harvesting systems for greenhouse crops; however, reliable operation under fruit occlusion and clustered arrangements remains a major challenge, particularly due to the limited integration between perception and motion planning modules. The paper presents the design and experimental validation of an autonomous robotic system for greenhouse tomato harvesting. The proposed platform integrates a rail-guided mobile base, a six-degrees-of-freedom robotic manipulator, and an adaptive end effector with a hybrid vision framework that combines convolutional neural networks and watershed-based segmentation to enable robust fruit detection and localization under occluded conditions. The proposed approach enables improved separation of overlapping fruits and provides accurate spatial localization through stereo vision combined with IMU-assisted camera-to-robot coordinate transformation. An occlusion-aware trajectory planning strategy was developed to generate collision-free manipulation paths in the presence of leaves and stems, enhancing harvesting safety and reliability. The system was trained and evaluated using a dataset of real greenhouse images supplemented with synthetic data augmentation. Experimental trials conducted under practical greenhouse conditions demonstrated a fruit detection precision of 96.9%, recall of 93.5%, and mean Intersection-over-Union of 79.2%. The robotic platform achieved an overall harvesting success rate of 78.5%, reaching 85% for unobstructed fruits, with an average cycle time of 15 s per fruit in direct harvesting scenarios. The rail-guided mobility significantly improved positioning stability and repeatability during manipulation compared with fully mobile platforms. The results confirm that integrating hybrid perception with occlusion-aware motion planning can substantially improve the functionality of robotic harvesting systems in protected cultivation environments. The proposed solution contributes to the advancement of automation technologies for greenhouse vegetable production and supports the transition toward more sustainable and labor-efficient agricultural practices. Full article

Accurate trajectory tracking of redundant manipulators is difficult because the controller must simultaneously model local couplings between adjacent joints and global dependencies across the whole kinematic chain. Existing reinforcement learning methods typically employ multilayer perceptrons, which do not explicitly exploit manipulator structure and therefore show limited stability and representation ability in high-dimensional continuous control tasks. This paper proposes GT-TD3, a Graph Transformer-enhanced-Twin Delayed Deep Deterministic Policy Gradient framework, for redundant manipulator trajectory tracking. The proposed actor first converts the raw system state into joint-level node features and uses a graph neural network to extract local kinematic coupling information. A Transformer is then employed to capture long-range dependencies among joints. To strengthen the use of structural priors, topology- and distance-related bias terms are incorporated into the attention mechanism, enabling the network to encode manipulator structure during global feature learning. Experiments on a 7-DoF KUKA iiwa manipulator in PyBullet demonstrate that GT-TD3 outperforms MLP, pure GNN, and pure Transformer baselines in tracking performance. The proposed method achieves more stable training, faster convergence, and smoother and more accurate end-effector motion. The results show that the integration of local graph modeling and structure-aware global attention provides an effective solution for high-precision trajectory tracking of redundant manipulators. Full article

This paper proposes a hybrid control method for a 6-DOF robot arm using dynamic impedance to achieve stability, high precision, and robustness simultaneously. Conventional impedance control with fixed inertia, viscosity, and stiffness values lacks robustness against changes in working conditions. The proposed method designs an impedance model for the end-effector and performs position control by adding force-based displacement corrections to the target position for force-controlled axes. Dynamic impedance is realized by relating impedance characteristics to joint angles and angular velocities through the final value theorem and quadratic form transient response analysis. MATLAB/Simulink simulations of wall-wiping motion using an RPY-type 6-DOF robot verify the effectiveness of the proposed method. Full article

Existing robot end-effectors design methods lack structured domain prior knowledge support and have insufficient interaction with the environment, making it difficult to guarantee the accuracy of the design results. An adaptive design method is proposed that deeply embeds domain knowledge of end effectors into the design process, treats key design parameters as environmental variables, and optimizes them adaptively through reinforcement learning algorithms in perception and feedback. In a simulation environment constructed by combining a knowledge graph, a two-finger translational gripper is used as an example robot end-effector to acquire target data via sensors, and reinforcement learning is used to adaptively optimize the gripper’s key parameters. Experiments are conducted on a simulation platform with three typical tasks, yielding the optimal parameter range. Compared to the proximal policy optimization (PPO) algorithm, which has no prior knowledge input, the knowledge graph embedding proximal policy optimization (KGPPO) algorithm improves the average reward for gripper length and gripper force by 63.96% and 43.09%, respectively, for grasping eggs. The KGPPO algorithm achieves the highest average reward and the best stability compared with other algorithms. Experiments show that this method can significantly improve the efficiency, stability, and accuracy of design parameter optimization. Full article

The irregular geometry of highway tunnel linings, combined with uneven terrain and external disturbances, often causes inspection robots to deviate from their predefined paths. Due to the strong coupling inherent in robotic systems, these deviations propagate to the end-effector, significantly compromising automated inspection accuracy and effectiveness. To tackle these issues, this study introduces an Enhanced Extended Sliding Mode Predictive Control (EESMPC) method, which integrates an adaptive Extended State Observer (ESO). The algorithm is derived from the robot chassis model and a desired trajectory error model, enabling precise contour profile tracking. Crucially, the integrated ESO actively estimates and compensates for unmodeled disturbances and system uncertainties within the state feedback, thereby enhancing both path tracking stability and precision. Comparative MATLAB simulations and experimental path tracking tests evaluated the performance against three other controllers. The results demonstrate that the EESMPC algorithm achieves superior tunnel lining tracking performance, exhibiting marked improvements in both tracking accuracy and system robustness. Consequently, this approach significantly enhances the automated inspection accuracy and operational efficiency of highway tunnel inspection robots. Full article

Neuronal function relies on the precise coordination between intracellular calcium (Ca²⁺) signaling and the cytoskeletal architecture that underpins synaptic transmission, plasticity, and structural stability. Disruption of this calcium–cytoskeleton interplay has been noted in numerous neurodegenerative diseases. We discuss how Ca²⁺-dependent cytoskeletal remodeling governs long-term potentiation and depression, dendritic spine morphology, and presynaptic function, highlighting the functions of end-binding proteins, STIM (Stromal Interaction Molecule)/Orai-mediated store-operated calcium entry, and the spine apparatus. Disease-specific manifestations of cytoskeletal–calcium dysregulation are reviewed across Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, tauopathies, and prion disorders. Finally, we evaluate emerging therapeutic strategies targeting calcium homeostasis, cytoskeletal dynamics, and their downstream effectors, including multi-target approaches. Full article

As critical end-effectors enabling the practical deployment of marine robotic systems, soft hands face persistent challenges including multi-finger asynchronization, unbalanced force distribution, and insufficient anti-disturbance robustness, compounded by constraints from soft material nonlinearity and harsh marine environmental disturbances. To address these limitations, this paper proposes a dexterous grasping method integrating coupled dynamical systems and adaptive force planning control, designed to enhance operational reliability in complex marine environments. An intermediate dynamic layer is embedded to ensure precise multi-finger synchronization, a hybrid force planning algorithm balances force uniformity and constraint satisfaction, and an adaptive controller synergizes with a Neo-Hookean model to compensate for nonlinear deviations. Simulations and physical experiments demonstrate that the method delivers excellent grasping stability and accuracy for uneven mass distribution targets such as cylinders and spheres, while balancing synchronization precision, constraint compliance, and anti-disturbance capability. Compared with the traditional coupled dynamical systems (DSs), the constraint violation is reduced by up to 18.2%, the friction force is increased by 4.0%, and the force distribution uniformity is improved by approximately 5.1%.Compared with the particle swarm optimization (PSO) strategy, the constraint violation is reduced by up to 50.5%, the friction force is increased by 40.9%, and the force distribution uniformity is also improved by about 5.1%. This work fills a key gap in balancing multiple performance metrics for marine soft hands, providing a reliable technical solution to accelerate the real-world deployment of marine robotic systems. Full article

This paper investigates robotic surface-to-surface object transfer, a release manipulation task in which a robot transfers an object from an end-effector that functions solely as a large supporting surface to an external surface such as the ground. Such transfers commonly arise in many practical manipulation scenarios. Unlike simple releasing actions, surface-to-surface transfer requires maintaining force equilibrium through controlled rolling and sliding at the contact interfaces. We present a manipulation model that captures the essential contact kinematics and enables force balance throughout the transfer. To assess robustness, we introduce a stability simulation framework that evaluates dynamic stability by monitoring variations in gravitational potential energy across object configurations. The proposed approach is implemented on a quadrupedal robot and validated through a series of experiments with objects of varying geometries. The results demonstrate the effectiveness of the method and underscore the role of stability-aware control in surface-to-surface transfer. Full article

This article presents the findings of experimental research conducted to assess the stability of the force mode of the UR5e cobot from Universal Robots in the low-force range, from 1 N to 10 N. The set values of the robot’s forces and the physically measured values were verified by an OptoForce Hex six-axis Force/Torque sensor attached to the robot’s wrist, additionally coupled with an end-effector specially designed for research purposes. The results were recorded using proprietary software developed in the LabVIEW environment and a configured test lab station with a UR5e cobot. Three experimental tests were performed, in which the parameters of the effective force were measured while varying (1) the position of the task in the workspace of the robot, (2) the position and the level of force, and (3) the controller parameters of the force mode. The results of the experiments were compiled and presented in tables containing descriptions of, among other parameters, the following: the mean forces and their standard deviation; the mean maximum forces and its standard deviation; the mean root mean square error and its standard deviation; the mean absolute error and its standard deviation; the mean rate of force and its standard deviation; and the mean overshoot and its standard deviation. The findings of Experiment 1 demonstrated that when a setpoint of 10 N was employed, the UR5e cobot yielded an actual mean force ranging from 8.95 N to 13.26 N within the workspace plane. Experiment 2 showed that the average deviation from the set value within the 1–10 N range was approximately 0.38 N, with a maximum deviation of 0.61 N occurring at the limits of the working space. Experiment 3 showed that for the force range of 1–4 N, the best controller settings are Gain = 0.5 and Damping = 0.7; for the force range of 5–7 N: Gain = 1.0 and Damping = 0.6; and for the force range of 8–10 N: Gain = 2.0 and Damping = 0.8. Polynomial regression models were developed for each positioning scenario that can be used when making decisions regarding practical applications of the low-force mode. Full article

Position-Based Visual Servoing (PBVS) and Image-Based Visual Servoing (IBVS) struggle to balance end effector pose accuracy and robustness in apple picking. They are also prone to target loss and control singularities. A progressive Hybrid Automatic Switching Visual Servoing (HAVS) method is proposed and applied to an apple-picking robotic system. HAVS integrates PBVS and IBVS to coordinate control of the manipulator end effector pose. A depth-based switching function is designed. When target depth is below an optimal threshold, the controller switches to PBVS for precise final positioning. This reduces target loss and control singularities. An adaptive proportional-derivative (PD) controller with fuzzy gain scheduling updates the control gains online to enhance responsiveness and stability. The hardware consists of a six-axis manipulator, a depth camera, and a mobile base. You Only Look Once version 5 (YOLOv5) performs apple detection and generates control commands. Indoors, success rate was 96%, which was 4 and 10 percentage points higher than PBVS only and IBVS only. Average picking time was 12.5 s, 0.3 s, and 1.1 s shorter. Outdoors, success rate was 87.5%, average time was 13.2 s, and damage rate was 4.2%. This method provides a reference implementation for visual servo control in agricultural picking robots. Full article

Wall-climbing robots are increasingly required for applications in aerospace, high-altitude operations, and complex environmental monitoring, where they must maintain reliable adhesion and continuous mobility across surfaces with rapidly changing material properties and roughness. Achieving these demands requires lightweight systems with end effectors that integrate multi-surface adaptability and load-carrying capacity. Current single adhesion mechanisms are typically effective only under specific wall conditions, making it challenging to achieve stable, continuous adhesion and detachment on surfaces with significantly different roughness. To address this limitation, we propose a flexible, multi-mechanism coupled end effector driven by a pneumatic–cable hybrid system, integrating two complementary adhesion mechanisms—claw-based interlocking and vacuum suction—into a unified flexible structure. First, we develop the overall structural framework of the end effector and conduct finite element simulations to analyze key structural parameters of the telescopic cavity. We then establish a contact force model between the claw and vertical rough surfaces to clarify the interlocking adhesion mechanism and determine critical geometric parameters. Based on these analyses, a cable-driven adjustment mechanism is introduced to enable dynamic self-adaptation and assist with load-bearing during adhesion, enhancing the stability and load-carrying capacity under varying wall conditions. On rough surfaces, the end effector achieves reliable adhesion through claw interlocking, while on smooth surfaces, it maintains stable attachment through vacuum suction. Furthermore, it supports seamless switching between adhesion modes on different surfaces. When integrated into a wall-climbing robot, the system enables stable adhesion and detachment on both rough and smooth surfaces, providing a feasible solution for the lightweight, integrated design of end effectors for multi-surface adaptive wall-climbing robots. Full article

RNA dysregulation mediated by aberrant RNA-binding proteins (RBPs) is closely associated with tumorigenesis. However, the tumorigenic mechanisms of each RBP remained unclear. In this study, we demonstrate that downregulation of Splicing factor 3A1 (SF3A1) markedly suppressed the proliferation of colorectal cancer (CRC) cells, with minimal cytotoxicity observed in non-cancerous epithelial cells. The tumor-promoting function of SF3A1 was further validated in an HCT116 xenograft mouse model. Multiple apoptosis assays—including TdT-mediated dUTP nick end labeling (TUNEL) staining, poly-ADP-ribose polymerase (PARP) immunoblotting, and caspase-3/7 activity measurements—showed that SF3A1 inhibited apoptotic signaling in CRC cells. Transcriptome analysis, combined with RNA-immunoprecipitation (RIP), identified Syntaxin 12 (STX12) as a downstream effector of SF3A1. Knockdown of STX12 induced apoptosis in CRC cells but had no effect on the viability of non-cancerous HCEC-1CT epithelial cells. Furthermore, STX12 mRNA levels were significantly reduced following SF3A1 knockdown, indicating that SF3A1-mediated stabilization of STX12 contributes to apoptosis resistance in CRC cells. Collectively, our findings establish that SF3A1 promotes CRC progression by stabilizing STX12 mRNA and selectively inhibiting apoptosis in malignant cells, thereby identifying the SF3A1–STX12 regulatory axis as a novel and selective therapeutic target for CRC. Full article

Shipborne UAV-assisted dock is an important way to recover unmanned systems for remote water surface low-altitude detection. The lack of resisting deck disturbances capability for UAV autonomous landing in dynamic dock stations has led to the inability of traditional hovering recovery methods for single UAV guidance and flight attitude control systems to meet the growing demand for landing assistance. In this work, we present a shipborne manipulator arm designed to grasp drones that use low-altitude visual servo technology for landing on the water surface. The shipborne manipulator arm is fabricated as a key component of a seaplane drone dock comprising a ship-type embedded drone storage, a packaged helistop for power transfer and UAV recovery, and a multi-degree-of-freedom arm integrated with multi-source information sensors for the treatment of air-to-water-related airplane crashes. Dynamic model tests have demonstrated that the end-effector of the shipborne manipulator arm stabilizes and performs optimally for water surface disturbances. A down-to-top grasp docking paradigm for a UAV-assisted perching on a shipborne helistop that enables the charging components of the station system to be equipped automatically to ensure that the drone performs its mission in the best condition is also presented. The surface grasp experiments have verified the efficacy of this grasp paradigm when compared to the traditional autonomous landing method. Full article

Recent advances in legged robotics have highlighted deep reinforcement learning (DRL)-based controllers for their robust adaptability to diverse, unstructured environments. While position-based DRL controllers achieve high tracking accuracy, they offer limited disturbance rejection, which degrades walking stability; torque-based DRL controllers can mitigate this issue but typically require extensive time and trial-and-error to converge. To address these challenges, we propose a Real-Time Motion Generator (RTMG). At each time step, RTMG kinematically synthesizes end-effector trajectories from target translational and angular velocities (yaw rate) and step length, then maps them to joint angles via inverse kinematics to produce imitation data. The RL agent uses this imitation data as a torque bias, which is gradually annealed during training to enable fully autonomous behavior. We further combine the RTMG-generated imitation data with a decaying action priors scheme to ensure both initial stability and motion diversity. The proposed training pipeline, implemented in NVIDIA Isaac Gym with Proximal Policy Optimization (PPO), reliably converges to the target gait pattern. The trained controller is Tensor RT-optimized and runs at 50 Hz on a Jetson Nano; relative to a position-based baseline, torso oscillation is reduced by 24.88% in simulation and 21.24% on hardware, demonstrating the effectiveness of the approach. Full article