Search Results (1,302)

Whilst there has been an increasing trend of women holding academic positions in European Higher Tertiary Institutions (HTIs), leadership positions are held predominantly by men. The study draws on radical feminism theory with which its methodology is aligned by investigating the perceptions of both genders. To that end, the study categorizes the impediments holding women back from breaking the glass ceiling into endogenous and exogenous factors. By doing so, the authors are in a better position to recommend the implementation of policies and procedures to address this inequality and navigate towards achieving sustainable gender equality. The research was conducted using an online survey questionnaire administered among all academic and administrative staff of universities in the Republic of Cyprus, the country with the highest glass ceiling in the EU. The authors found that the binary genders differ in their perceptions of what keeps women from breaking the glass ceiling and that this is attributable to exogenous factors, namely, (a) the walls created by male leaders, reinforcing a feeling of marginalization and mansplaining; and (b) family obligations enhancing women’s experiencing a lack of time and burnout. Furthermore, the exogenous factors and the extremely gendered higher echelons of HTIs underpin the endogenous factor of self-sabotage, making women feel they would rather avoid the toxic leadership environment with its lack of professional credit, a view supported by radical feminism theory. The authors suggest practical policy implications to rectify the gender imbalance in leadership in HTIs and suggest directions for future research. Full article

Identifying predictors of pro-environmental behaviors (PEBs) can not only figure out who concerns about the environment most but also inform possible pathways that advance or inhabit such prosocial actions. Most past studies and theories focus on factors that reside within personal characteristics or sociopsychological mechanisms rather than taking a holistic view that integrates these two elements into a framework. This study investigates how socioeconomic status (SES) correlates with PEBs, integrating both structural and psychological mechanisms. Drawing on the Stimulus–Organism–Response (SOR) theoretical framework, this paper examines the paradox whereby individuals with higher SES exhibit more frequent environmental actions yet demonstrate lower willingness to pay (WTP)—a form of economic sacrifice. Using nationally representative data from the 2021 Chinese General Social Survey (CGSS), our structural equation modeling reveals that adulthood SES positively correlates with environmental values and behaviors but negatively correlates with WTP. This challenges the traditional linear assumption that greater willingness necessarily leads to greater action. Additionally, while childhood SES predicts adult SES, it shows no direct effect on environmental engagement. These findings highlight multidimensional pathways by which SES shape environmental actions, necessitating differentiated policy approaches to build a sustainable world. Full article

Extracellular vesicle (EV)-based therapies have attracted considerable attention as a novel class of biologics with broad clinical potential. However, their clinical translation is impeded by the fragmented and rapidly evolving regulatory landscape, with significant disparities between the United States, European Union, and key Asian jurisdictions. In this review, we systematically analyze regional guidelines and strategic frameworks governing EV therapeutics, emphasizing critical hurdles in quality control, safety evaluation, and efficacy demonstration. We further explore the implications of EVs’ heterogeneity on product characterization and the emerging direct-to-consumer market for EVs and secretome preparations. Drawing on these insights, in this review, we aim to provide a roadmap for harmonizing regulatory requirements, advancing standardized analytical approaches, and fostering ongoing collaboration among regulatory authorities, industry stakeholders, and academic investigators. Such coordinated efforts are essential to safeguard patient welfare, ensure product consistency, and accelerate the responsible integration of EV-based interventions into clinical practice. Full article

Rapid urbanization and escalating disaster risks necessitate resilient urban governance systems. Smart city initiatives that leverage digital technologies—such as the internet of things (IoT), big data analytics, and artificial intelligence (AI)—demonstrate transformative potential in enhancing emergency management capabilities. However, empirical evidence regarding their causal impact and underlying mechanisms remains limited, particularly in developing economies. Drawing on panel data from 275 Chinese prefecture-level cities over the period 2006–2021 and using China’s smart city pilot policy as a quasi-natural experiment, this study applies a multi-period difference-in-differences (DID) approach to rigorously assess the effects of smart city construction on emergency management capabilities. Results reveal that smart city construction produced a statistically significant improvement in emergency management capabilities, which remained robust after conducting multiple sensitivity checks and controlling for potential confounding policies. The benefits exhibit notable heterogeneity: emergency management capability improvements are most pronounced in central China and in cities at the extremes of population size—megacities (>10 million residents) and small cities (<1 million residents)—while effects remain marginal in medium-sized and eastern cities. Crucially, mechanism analysis reveals that digital technology application fully mediates 86.7% of the total effect, whereas factor allocation efficiency exerts only a direct, non-mediating influence. These findings suggest that smart cities primarily enhance emergency management capabilities through digital enablers, with effectiveness contingent upon regional infrastructure development and urban scale. Policy priorities should therefore emphasize investments in digital infrastructure, interagency data integration, and targeted capacity-building strategies tailored to central and western regions as well as smaller cities. Full article

This study introduces the concept of DEEPEIA, a novel deep learning (DL) platform designed to recommend the optimal export market, and its ideal foreign champion, for any product or service offered by a small and medium-sized enterprise (SME). Drawing on expertise in SME internationalization and leveraging recent advances in generative artificial intelligence (AI), this research addresses key challenges faced by SMEs in global expansion. A systematic review of existing platforms was conducted to identify current gaps and inform the conceptualization of an advanced generative DL recommender system. The Discussion section proposes the conceptual framework for such a decision optimizer within the context of contemporary technological advancements and actionable insights. The conclusion outlines future research directions, practical implementation strategies, and expected obstacles. By mapping the current landscape and presenting an original forecasting tool, this work advances the field of AI-enabled SME internationalization while still acknowledging that more empirical validation remains a necessary next step. Full article

This study investigates the impact and mechanisms of digital inclusive finance (DIF) on high-quality economic development in China. Drawing on panel data from 281 prefecture-level cities between 2011 and 2021, we employ a Spatial Durbin Model (SDM) to analyze both the direct effects and spatial spillovers of DIF. The results indicate that (1) DIF has a significantly positive effect on high-quality development, which remains robust after conducting various stability and endogeneity tests; (2) DIF strongly contributes to economic upgrading in eastern regions, while its impact is weaker or even negative in central and western regions, revealing notable regional disparities exist; (3) a key finding is the identification of a double-threshold effect, suggesting that the positive influence of DIF only emerges when financial and industrial development surpass certain thresholds; (4) results from the two-regime SDM further show that spillover effects are more prominent in non-central cities than in central ones; and (5) mechanism analysis reveals that DIF facilitates high-quality growth primarily by promoting industrial structure upgrading. These findings underscore the importance of region-specific policy strategies to enhance the role of DIF and reduce spatial disparities in development across China. Full article

Healthcare supply chain management operates amid fluctuating patient demand, rapidly advancing biotechnologies, and unpredictable supply disruptions pose high risks and create an imperative for sustainable resource optimization. This study investigates the underlying mechanisms through which digital intelligence drives strategic decision optimization in healthcare supply chains. Drawing on the Resource-Based View and Dynamic Capabilities Theory, we develop a chain-mediated model, defined as the multistage indirect path whereby digital intelligence first bolsters innovation capability, which then activates supply chain resilience (absorptive, response, and restorative capability), to improve decision optimization. Data were collected from 360 managerial-level respondents working in healthcare supply chain organizations in China, and the proposed model was tested using structural equation modeling. The results indicate that digital intelligence enhances innovation capability, which in turn activates all three dimensions of resilience, producing a synergistic effect that promotes sustained decision optimization. However, the direct effect of digital intelligence on decision optimization was not statistically significant, suggesting that its impact is primarily mediated through organizational capabilities, particularly supply chain resilience. Practically, the findings suggest that in the process of deploying digital intelligence systems and platforms, healthcare organizations should embed technological advantages into organizational processes, emergency response mechanisms, and collaborative operations, so that digitalization moves beyond the technical system level and is truly internalized as organizational innovation capability and resilience, thereby leading to sustained improvement in decision-making performance. Full article

This study aims to evaluate the sustainability performance of EU regions through a comprehensive and data-driven Environmental, Social, Governance (ESG) framework, addressing the increasing demand for regional-level analysis in sustainable finance and policy design. Leveraging Partial Least Squares (PLS) regression and cluster analysis, we construct composite ESG indicators that adjust for economic size using GDP normalization and LOESS smoothing. Drawing on panel data from 2010 to 2023 and over 170 indicators, we model the determinants of ESG performance at both the national and regional levels across the EU-27. Time-based ESG trajectories are assessed using Compound Annual Growth Rates (CAGR), capturing resilience to shocks such as the COVID-19 pandemic and geopolitical instability. Our findings reveal clear spatial disparities in ESG performance, highlighting the structural gaps in governance, environmental quality, and social cohesion. The model captures patterns of convergence and divergence across EU regions and identifies common drivers influencing sustainability outcomes. This paper introduces an integrated framework that combines PLS regression, clustering, and time-based trend analysis to assess ESG performance at the subnational level. The originality of this study lies in its multi-layered approach, offering a replicable and scalable model for evaluating sustainability with direct implications for green finance, policy prioritization, and regional development. This study contributes to the literature by applying advanced data-driven techniques to assess ESG dynamics in complex economic systems. Full article

Small Language Models (SLMs) have emerged as a critical area of study within natural language processing, attracting growing attention from both academia and industry. This systematic literature review provides a comprehensive and reproducible analysis of recent developments and advancements in SLMs post-2023. Drawing on 70 English-language studies published between January 2023 and January 2025, identified through Scopus, IEEE Xplore, Web of Science, and ACM Digital Library, and focusing primarily on SLMs (including those with up to 7 billion parameters), this review offers a structured overview of the current state of the art and potential future directions. Designed as a resource for researchers seeking an in-depth global synthesis, the review examines key dimensions such as publication trends, visual data representations, contributing institutions, and the availability of public datasets. It highlights prevailing research challenges and outlines proposed solutions, with a particular focus on widely adopted model architectures, as well as common compression and optimization techniques. This study also evaluates the criteria used to assess the effectiveness of SLMs and discusses emerging de facto standards for industry. The curated data and insights aim to support and inform ongoing and future research in this rapidly evolving field. Full article

This article presents a scoping review of the academic literature published between 2021 and 2024 on the intersection of generative artificial intelligence (AI) and disinformation. Drawing from 64 peer-reviewed studies, the review examines the current research landscape and identifies six key thematic areas: political disinformation and propaganda; scientific disinformation; fact-checking; journalism and the media; media literacy and education; and deepfakes. The findings reveal that generative AI plays a dual role: it enables the rapid creation and targeted dissemination of synthetic content but also offers new opportunities for detection, verification, and public education. Beyond summarizing research trends, this review highlights the broader societal and practical implications of generative AI in the context of information disorder. It outlines how AI tools are already reshaping journalism, challenging scientific communication, and transforming strategies for media literacy and fact-checking. The analysis also identifies key policy and governance challenges, particularly the need for coordinated responses from governments, platforms, educators, and civil society actors. By offering a structured overview of the field, the article enhances our understanding of how generative AI can both exacerbate and help mitigate disinformation, and proposes directions for research, regulation, and public engagement. Full article

Spinal cord injury (SCI) remains one of the toughest obstacles in neuroscience and regenerative medicine due to both severe functional loss and limited healing ability. This article aims to provide a key integrative, mechanism-focused review of the molecular landscape of SCI and the new disruptive therapy technologies that are now evolving in the SCI arena. Our goal is to unify a fundamental pathophysiology of neuroinflammation, ferroptosis, glial scarring, and oxidative stress with the translation of precision treatment approaches driven by artificial intelligence (AI), CRISPR-mediated gene editing, and regenerative bioengineering. Drawing upon advances in single-cell omics, systems biology, and smart biomaterials, we will discuss the potential for reprogramming the spinal cord at multiple levels, from transcriptional programming to biomechanical scaffolds, to change the course from an irreversible degeneration toward a directed regenerative pathway. We will place special emphasis on using AI to improve diagnostic/prognostic and inferred responses, gene and cell therapies enabled by genomic editing, and bioelectronics capable of rehabilitating functional connectivity. Although many of the technologies described below are still in development, they are becoming increasingly disruptive capabilities of what it may mean to recover from an SCI. Instead of prescribing a particular therapeutic fix, we provide a future-looking synthesis of interrelated biological, computational, and bioengineering approaches that conjointly chart a course toward adaptive, personalized neuroregeneration. Our intent is to inspire a paradigm shift to resolve paralysis through precision recovery and to be grounded in a spirit of humility, rigor, and an interdisciplinary approach. Full article

This article examines how research-and-development (R&D) expenditure—as a share of GDP—both in total and disaggregated by sector (business enterprise and government)—shapes key socioeconomic outcomes in the EU-27. Drawing on Eurostat panel data for 2013–2022, we estimate fixed- and random-effects models with sector-specific lags. Business R&D expenditure is associated with lower female and male unemployment and faster GDP growth. Government R&D expenditure, by contrast, widens the gender pay gap and dampens GDP per capita after two years, although it attracts foreign direct investment in the short and medium term. The diminishing impact of R&D over time underscores the need for policies that sustain innovation benefits. Full article

Endophytic microorganisms inhabiting plant tissues constitute a unique and largely untapped reservoir of bioactive metabolites, including phenolics, terpenoids, alkaloids, polysaccharides, and anthraquinones, among others. This review focuses on the potential of these compounds to modulate the complex processes of wound repair, such as hemostasis, inflammation, proliferation, and remodeling. Uniquely, this review delineates the specific mechanisms supported not only by indirect evidence but by primary research directly linking endophytic metabolites to wound repair. We synthesized and evaluated evidence from 18 studies, of which over 75% directly assessed wound healing effects through in vitro and in vivo models. Metabolites from endophytic microorganisms promoted wound contraction, suppressed biofilm formation by key pathogens (e.g., MRSA, P. aeruginosa), and accelerated tissue re-epithelialization in animal models. Other compounds demonstrated >99% wound closure in rats, while several extracts showed anti-inflammatory and cytocompatible profiles. Nevertheless, the majority of studies applied unstandardized methods and used crude extracts, hindering precise structure–activity assessment. The originality of this review lies in drawing attention to direct evidence for wound healing from diverse endophytic sources and systematically identifying gaps between preclinical promise and clinical translation, positioning endophytes as a sustainable platform for next-generation wound therapeutics. Full article

This study explores how artificial intelligence (AI) technologies can be theoretically integrated into literature curriculum development, using the works of Anton Chekhov and Lu Xun as illustrative case texts. The aim is to reduce barriers to language and cultural understanding in literature education and increase the efficiency and accessibility of cross-cultural teaching. We used natural language processing (NLP) techniques to analyze textual features, such as readability index, lexical density, and syntactic complexity, of AI-generated and human-translated “The Chameleon” and “A Madman’s Diary”. Teaching cases from universities in China, Russia, and Kazakhstan are reviewed to assess the emerging practice of AI-supported literature teaching. The proposed theoretical framework draws on hermeneutics, posthumanism, and cognitive load theories. The results of the data-driven analysis suggest that AI-assisted translation tends to simplify sentence structure and improve surface readability. While anecdotal classroom observations highlight the role of AI in initial comprehension, deeper literary interpretation still relies on teacher guidance and critical human engagement. This study introduces a conceptual “AI Literature Teaching Model” that positions AI as a cognitive and cultural mediator and outlines directions for future empirical validation. Full article

To investigate the evolution trend of the extraction zone above the drawbell in block caving, an experimental apparatus incorporating the drawbell structure was designed. Ore drawing experiments were conducted using materials with varying particle size gradations. The results demonstrate that the extraction zones for all three gradations exhibit an ellipsoidal shape in the vertical direction, with elliptical cross-sections. As the draw height increases, both the major and minor axes of the extraction zone’s maximum cross-section continuously enlarge, stabilizing beyond a draw height of 80 cm. The ore fragment size significantly influences the extraction zone dimensions. Gradation I, characterized by the smallest average particle size, yielded the largest extraction zone, whereas Gradation III, with the largest average particle size, resulted in the smallest. Numerical simulations of ore drawing for the different particle sizes were performed using PFC3D. The extent of the extraction zone in the numerical results was determined by reconstructing the initial positions of the drawn particles. The simulations show good agreement with the experimental findings, particularly regarding how the major and minor axes of the extraction zone cross-section vary with increasing draw height. Moreover, the simulations confirm that smaller average particle sizes enhance particle flowability, leading to larger extraction zones, as anticipated. Full article