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20 pages, 4961 KiB  
Article
Optimization of Thermal Conductivity of Bismaleimide/h-BN Composite Materials Based on Molecular Structure Design
by Weizhuo Li, Run Gu, Xuan Wang, Chenglong Wang, Mingzhe Qu, Xiaoming Wang and Jiahao Shi
Polymers 2025, 17(15), 2133; https://doi.org/10.3390/polym17152133 (registering DOI) - 3 Aug 2025
Abstract
With the rapid development of information technology and semiconductor technology, the iteration speed of electronic devices has accelerated in an unprecedented manner, and the market demand for miniaturized, highly integrated, and highly intelligent devices continues to rise. But when these electronic devices operate [...] Read more.
With the rapid development of information technology and semiconductor technology, the iteration speed of electronic devices has accelerated in an unprecedented manner, and the market demand for miniaturized, highly integrated, and highly intelligent devices continues to rise. But when these electronic devices operate at high power, the electronic components generate a large amount of integrated heat. Due to the limitations of existing heat dissipation channels, the current heat dissipation performance of electronic packaging materials is struggling to meet practical needs, resulting in heat accumulation and high temperatures inside the equipment, seriously affecting operational stability. For electronic devices that require high energy density and fast signal transmission, improving the heat dissipation capability of electronic packaging materials can significantly enhance their application prospects. In order to improve the thermal conductivity of composite materials, hexagonal boron nitride (h-BN) was selected as the thermal filling material in this paper. The BMI resin was structurally modified through molecular structure design. The results showed that the micro-branched structure and h-BN synergistically improved the thermal conductivity and insulation performance of the composite material, with a thermal conductivity coefficient of 1.51 W/(m·K) and a significant improvement in insulation performance. The core mechanism is the optimization of the dispersion state of h-BN filler in the matrix resin through the free volume in the micro-branched structure, which improves the thermal conductivity of the composite material while maintaining high insulation. Full article
(This article belongs to the Special Issue Electrical Properties of Polymer Composites)
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17 pages, 2085 KiB  
Article
Identification Method of Weak Nodes in Distributed Photovoltaic Distribution Networks for Electric Vehicle Charging Station Planning
by Xiaoxing Lu, Xiaolong Xiao, Jian Liu, Ning Guo, Lu Liang and Jiacheng Li
World Electr. Veh. J. 2025, 16(8), 433; https://doi.org/10.3390/wevj16080433 (registering DOI) - 2 Aug 2025
Abstract
With the large-scale integration of high-penetration distributed photovoltaic (DPV) into distribution networks, its output volatility and reverse power flow characteristics are prone to causing voltage violations, necessitating the accurate identification of weak nodes to enhance operational reliability. This paper investigates the definition, quantification [...] Read more.
With the large-scale integration of high-penetration distributed photovoltaic (DPV) into distribution networks, its output volatility and reverse power flow characteristics are prone to causing voltage violations, necessitating the accurate identification of weak nodes to enhance operational reliability. This paper investigates the definition, quantification criteria, and multi-indicator comprehensive determination methods for weak nodes in distribution networks. A multi-criteria assessment method integrating voltage deviation rate, sensitivity analysis, and power margin has been proposed. This method quantifies the node disturbance resistance and comprehensively evaluates the vulnerability of voltage stability. Simulation validation based on the IEEE 33-node system demonstrates that the proposed method can effectively identify the distribution patterns of weak nodes under different penetration levels (20~80%) and varying numbers of DPV access points (single-point to multi-point distributed access scenarios). The study reveals the impact of increased penetration and dispersed access locations on the migration characteristics of weak nodes. The research findings provide a theoretical basis for the planning of distribution networks with high-penetration DPV, offering valuable insights for optimizing the siting of volatile loads such as electric vehicle (EV) charging stations while considering both grid safety and the demand for distributed energy accommodation. Full article
(This article belongs to the Special Issue Fast-Charging Station for Electric Vehicles: Challenges and Issues)
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27 pages, 3806 KiB  
Article
Dynamic Evolution and Resilience Enhancement of the Urban Tourism Ecological Health Network: A Case Study in Shanghai, China
by Man Wei and Tai Huang
Systems 2025, 13(8), 654; https://doi.org/10.3390/systems13080654 (registering DOI) - 2 Aug 2025
Abstract
Urban tourism has evolved into a complex adaptive system, where unregulated expansion disrupts the ecological balance and intensifies resource stress. Understanding the dynamic evolution and resilience mechanisms of the tourism ecological health network (TEHN) is essential for supporting sustainable urban tourism as a [...] Read more.
Urban tourism has evolved into a complex adaptive system, where unregulated expansion disrupts the ecological balance and intensifies resource stress. Understanding the dynamic evolution and resilience mechanisms of the tourism ecological health network (TEHN) is essential for supporting sustainable urban tourism as a coupled human–natural system. Using Shanghai as a case study, we applied the "vigor–organization–resilience–services" (VORS) framework to evaluate ecosystem health, which served as a constraint for constructing the TEHN, using the minimum cumulative resistance (MCR) model for the period from 2001 to 2023. A resilience framework integrating structural and functional dimensions was further developed to assess spatiotemporal evolution and guide targeted enhancement strategies. The results indicated that as ecosystem health degraded, particularly in peripheral areas, the urban TEHN in Shanghai shifted from a dispersed to a centralized structure, with limited connectivity in the periphery. The resilience of the TEHN continued to grow, with structural resilience remaining at a high level, while functional resilience still required enhancement. Specifically, the low integration and limited choice between the tourism network and the transportation system hindered tourists from selecting routes with higher ecosystem health indices. Enhancing functional resilience, while sustaining structural resilience, is essential for transforming the TEHN into a multi-centered, multi-level system that promotes efficient connectivity, ecological sustainability, and long-term adaptability. The results contribute to a systems-level understanding of tourism–ecology interactions and support the development of adaptive strategies for balancing network efficiency and environmental integrity. Full article
(This article belongs to the Section Complex Systems and Cybernetics)
26 pages, 7634 KiB  
Article
Research on the Preparation and Performance of Wood with High Negative Oxygen Ion Release Induced by Moisture
by Min Yin, Yuqi Zhang, Yun Lu, Zongying Fu, Haina Mi, Jianfang Yu and Ximing Wang
Coatings 2025, 15(8), 905; https://doi.org/10.3390/coatings15080905 (registering DOI) - 2 Aug 2025
Abstract
With the growing severity of environmental pollution, people are paying increasing attention to their health. However, naturally occurring wood with health benefits and applications in human healthcare is still scarce. Natural wood exhibits a limited negative oxygen ion release capacity, and this release [...] Read more.
With the growing severity of environmental pollution, people are paying increasing attention to their health. However, naturally occurring wood with health benefits and applications in human healthcare is still scarce. Natural wood exhibits a limited negative oxygen ion release capacity, and this release has a short duration, failing to meet practical application requirements. This study innovatively developed a humidity-responsive, healthy wood material with a high negative oxygen ion release capacity based on fast-growing poplar. Through vacuum cyclic impregnation technology, hexagonal stone powder was infused into the pores of poplar wood, endowing it with the ability to continuously release negative oxygen ions. The healthy wood demonstrated a static average negative oxygen ion release rate of 537 ions/cm3 (peaking at 617 ions/cm3) and a dynamic average release rate of 3,170 ions/cm3 (peaking at 10,590 ions/cm3). The results showed that the particle size of hexagonal stone powder in suspension was influenced by the dispersants and dispersion processes. The composite dispersion process demonstrated optimal performance when using 0.5 wt% silane coupling agent γ-(methacryloxy)propyltrimethoxysilane (KH570), achieving the smallest particle size of 8.93 μm. The healthy wood demonstrated excellent impregnation performance, with a weight gain exceeding 14.61% and a liquid absorption rate surpassing 165.18%. The optimal impregnation cycle for vacuum circulation technology was determined to be six cycles, regardless of the type of dispersant. Compared with poplar wood, the hygroscopic swelling rate of healthy wood was lower, especially in PEG-treated samples, where the tangential, radial, longitudinal, and volumetric swelling rates decreased by 70.93%, 71.67%, 69.41%, and 71.35%, respectively. Combining hexagonal stone powder with fast-growing poplar wood can effectively enhance the release of negative oxygen ions. The static average release of negative oxygen ions from healthy wood is 1.44 times that of untreated hexagonal stone powder, and the dynamic release reaches 2 to 3 times the concentration of negative oxygen ions specified by national fresh air standards. The water-responsive mechanism revealed that negative oxygen ion release surged when ambient humidity exceeded 70%. This work proposes a sustainable and effective method to prepare healthy wood with permanent negative oxygen ion release capability. It demonstrates great potential for improving indoor air quality and enhancing human health. Full article
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21 pages, 2077 KiB  
Article
Quantitative Risk Assessment of Liquefied Natural Gas Bunkering Hoses in Maritime Operations: A Case of Shenzhen Port
by Yimiao Gu, Yanmin Zeng and Hui Shan Loh
J. Mar. Sci. Eng. 2025, 13(8), 1494; https://doi.org/10.3390/jmse13081494 (registering DOI) - 2 Aug 2025
Abstract
The widespread adoption of liquefied natural gas (LNG) as a marine fuel has driven the development of LNG bunkering operations in global ports. Major international hubs, such as Shenzhen Port, have implemented ship-to-ship (STS) bunkering practices. However, this process entails unique safety risks, [...] Read more.
The widespread adoption of liquefied natural gas (LNG) as a marine fuel has driven the development of LNG bunkering operations in global ports. Major international hubs, such as Shenzhen Port, have implemented ship-to-ship (STS) bunkering practices. However, this process entails unique safety risks, particularly hazards associated with vapor cloud dispersion caused by bunkering hose releases. This study employs the Phast software developed by DNV to systematically simulate LNG release scenarios during STS operations, integrating real-world meteorological data and storage conditions. The dynamic effects of transfer flow rates, release heights, and release directions on vapor cloud dispersion are quantitatively analyzed under daytime and nighttime conditions. The results demonstrate that transfer flow rate significantly regulates dispersion range, with recommendations to limit the rate below 1500 m3/h and prioritize daytime operations to mitigate risks. Release heights exceeding 10 m significantly amplify dispersion effects, particularly at night (nighttime dispersion area at a height of 20 m is 3.5 times larger than during the daytime). Optimizing release direction effectively suppresses dispersion, with vertically downward releases exhibiting minimal impact. Horizontal releases require avoidance of downwind alignment, and daytime operations are prioritized to reduce lateral dispersion risks. Full article
(This article belongs to the Section Ocean Engineering)
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38 pages, 6505 KiB  
Review
Trends in Oil Spill Modeling: A Review of the Literature
by Rodrigo N. Vasconcelos, André T. Cunha Lima, Carlos A. D. Lentini, José Garcia V. Miranda, Luís F. F. de Mendonça, Diego P. Costa, Soltan G. Duverger and Elaine C. B. Cambui
Water 2025, 17(15), 2300; https://doi.org/10.3390/w17152300 (registering DOI) - 2 Aug 2025
Abstract
Oil spill simulation models are essential for predicting the oil spill behavior and movement in marine environments. In this study, we comprehensively reviewed a large and diverse body of peer-reviewed literature obtained from Scopus and Web of Science. Our initial analysis phase focused [...] Read more.
Oil spill simulation models are essential for predicting the oil spill behavior and movement in marine environments. In this study, we comprehensively reviewed a large and diverse body of peer-reviewed literature obtained from Scopus and Web of Science. Our initial analysis phase focused on examining trends in scientific publications, utilizing the complete dataset derived after systematic screening and database integration. In the second phase, we applied elements of a systematic review to identify and evaluate the most influential contributions in the scientific field of oil spill simulations. Our analysis revealed a steady and accelerating growth of research activity over the past five decades, with a particularly notable expansion in the last two. The field has also experienced a marked increase in collaborative practices, including a rise in international co-authorship and multi-authored contributions, reflecting a more global and interdisciplinary research landscape. We cataloged the key modeling frameworks that have shaped the field from established systems such as OSCAR, OIL-MAP/SIMAP, and GNOME to emerging hybrid and Lagrangian approaches. Hydrodynamic models were consistently central, often integrated with biogeochemical, wave, atmospheric, and oil-spill-specific modules. Environmental variables such as wind, ocean currents, and temperature were frequently used to drive model behavior. Geographically, research has concentrated on ecologically and economically sensitive coastal and marine regions. We conclude that future progress will rely on the real-time integration of high-resolution environmental data streams, the development of machine-learning-based surrogate models to accelerate computations, and the incorporation of advanced biodegradation and weathering mechanisms supported by experimental data. These advancements are expected to enhance the accuracy, responsiveness, and operational value of oil spill modeling tools, supporting environmental monitoring and emergency response. Full article
(This article belongs to the Special Issue Advanced Remote Sensing for Coastal System Monitoring and Management)
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20 pages, 2076 KiB  
Article
Numerical Modeling of Gentamicin Transport in Agricultural Soils: Implications for Environmental Pollution
by Nami Morales-Durán, Sebastián Fuentes, Jesús García-Gallego, José Treviño-Reséndez, Josué D. García-Espinoza, Rubén Morones-Ramírez and Carlos Chávez
Antibiotics 2025, 14(8), 786; https://doi.org/10.3390/antibiotics14080786 (registering DOI) - 2 Aug 2025
Abstract
Background/Objectives: In recent years, the discharge of antibiotics into rivers and irrigation canals has increased. However, few studies have addressed the impact of these compounds on agricultural fields that use such water to meet crop demands. Methods: In this study, the transport of [...] Read more.
Background/Objectives: In recent years, the discharge of antibiotics into rivers and irrigation canals has increased. However, few studies have addressed the impact of these compounds on agricultural fields that use such water to meet crop demands. Methods: In this study, the transport of two types of gentamicin (pure gentamicin and gentamicin sulfate) was modeled at concentrations of 150 and 300 μL/L, respectively, in a soil with more than 60 years of agricultural use. Infiltration tests under constant head conditions and gentamicin transport experiments were conducted in acrylic columns measuring 14 cm in length and 12.7 cm in diameter. The scaling parameters for the Richards equation were obtained from experimental data, while those for the advection–dispersion equation were estimated using inverse methods through a nonlinear optimization algorithm. In addition, a fractal-based model for saturated hydraulic conductivity was employed. Results: It was found that the dispersivity of gentamicin sulfate is 3.1 times higher than that of pure gentamicin. Based on the estimated parameters, two simulation scenarios were conducted: continuous application of gentamicin and soil flushing after antibiotic discharge. The results show that the transport velocity of gentamicin sulfate in the soil may have short-term consequences for the emergence of resistant microorganisms due to the destination of wastewater containing antibiotic residues. Conclusions: Finally, further research is needed to evaluate the impact of antibiotics on soil physical properties, as well as their effects on irrigated crops, animals that consume such water, and the soil microbiota. Full article
(This article belongs to the Special Issue Impact of Antibiotic Residues in Wastewater)
24 pages, 8010 KiB  
Article
Mono-(Ni, Au) and Bimetallic (Ni-Au) Nanoparticles-Loaded ZnAlO Mixed Oxides as Sunlight-Driven Photocatalysts for Environmental Remediation
by Monica Pavel, Liubovi Cretu, Catalin Negrila, Daniela C. Culita, Anca Vasile, Razvan State, Ioan Balint and Florica Papa
Molecules 2025, 30(15), 3249; https://doi.org/10.3390/molecules30153249 (registering DOI) - 2 Aug 2025
Abstract
A facile and versatile strategy to obtain NPs@ZnAlO nanocomposite materials, comprising controlled-size nanoparticles (NPs) within a ZnAlO matrix is reported. The mono-(Au, Ni) and bimetallic (Ni-Au) NPs serving as an active phase were prepared by the polyol-alkaline method, while the ZnAlO support was [...] Read more.
A facile and versatile strategy to obtain NPs@ZnAlO nanocomposite materials, comprising controlled-size nanoparticles (NPs) within a ZnAlO matrix is reported. The mono-(Au, Ni) and bimetallic (Ni-Au) NPs serving as an active phase were prepared by the polyol-alkaline method, while the ZnAlO support was obtained via the thermal decomposition of its corresponding layered double hydroxide (LDH) precursors. X-ray diffraction (XRD) patterns confirmed the successful fabrication of the nanocomposites, including the synthesis of the metallic NPs, the formation of LDH-like structure, and the subsequent transformation to ZnO phase upon LDH calcination. The obtained nanostructures confirmed the nanoplate-like morphology inherited from the original LDH precursors, which tended to aggregate after the addition of gold NPs. According to the UV-Vis spectroscopy, loading NPs onto the ZnAlO support enhanced the light absorption and reduced the band gap energy. ATR-DRIFT spectroscopy, H2-TPR measurements, and XPS analysis provided information about the functional groups, surface composition, and reducibility of the materials. The catalytic performance of the developed nanostructures was evaluated by the photodegradation of bisphenol A (BPA), under simulated solar irradiation. The conversion of BPA over the bimetallic Ni-Au@ZnAlO reached up to 95% after 180 min of irradiation, exceeding the monometallic Ni@ZnAlO and Au@ZnAlO catalysts. Its enhanced activity was correlated with good dispersion of the bimetals, narrower band gap, and efficient charge carrier separation of the photo-induced e/h+ pairs. Full article
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29 pages, 1132 KiB  
Article
Generating Realistic Synthetic Patient Cohorts: Enforcing Statistical Distributions, Correlations, and Logical Constraints
by Ahmad Nader Fasseeh, Rasha Ashmawy, Rok Hren, Kareem ElFass, Attila Imre, Bertalan Németh, Dávid Nagy, Balázs Nagy and Zoltán Vokó
Algorithms 2025, 18(8), 475; https://doi.org/10.3390/a18080475 (registering DOI) - 1 Aug 2025
Abstract
Large, high-quality patient datasets are essential for applications like economic modeling and patient simulation. However, real-world data is often inaccessible or incomplete. Synthetic patient data offers an alternative, and current methods often fail to preserve clinical plausibility, real-world correlations, and logical consistency. This [...] Read more.
Large, high-quality patient datasets are essential for applications like economic modeling and patient simulation. However, real-world data is often inaccessible or incomplete. Synthetic patient data offers an alternative, and current methods often fail to preserve clinical plausibility, real-world correlations, and logical consistency. This study presents a patient cohort generator designed to produce realistic, statistically valid synthetic datasets. The generator uses predefined probability distributions and Cholesky decomposition to reflect real-world correlations. A dependency matrix handles variable relationships in the right order. Hard limits block unrealistic values, and binary variables are set using percentiles to match expected rates. Validation used two datasets, NHANES (2021–2023) and the Framingham Heart Study, evaluating cohort diversity (general, cardiac, low-dimensional), data sparsity (five correlation scenarios), and model performance (MSE, RMSE, R2, SSE, correlation plots). Results demonstrated strong alignment with real-world data in central tendency, dispersion, and correlation structures. Scenario A (empirical correlations) performed best (R2 = 86.8–99.6%, lowest SSE and MAE). Scenario B (physician-estimated correlations) also performed well, especially in a low-dimensions population (R2 = 80.7%). Scenario E (no correlation) performed worst. Overall, the proposed model provides a scalable, customizable solution for generating synthetic patient cohorts, supporting reliable simulations and research when real-world data is limited. While deep learning approaches have been proposed for this task, they require access to large-scale real datasets and offer limited control over statistical dependencies or clinical logic. Our approach addresses this gap. Full article
(This article belongs to the Collection Feature Papers in Algorithms for Multidisciplinary Applications)
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14 pages, 1436 KiB  
Article
Secoisolariciresinol Diglucoside with Antioxidant Capacity from Flaxseed: A Study on Microwave-Assisted Germination Optimization
by Jinling Hu, Qingyi Zhang, Yaning Li, Qiqi Zhang, Caihua Jia, Fenghong Huang, Qianchun Deng and Cuie Tang
Foods 2025, 14(15), 2716; https://doi.org/10.3390/foods14152716 (registering DOI) - 1 Aug 2025
Viewed by 13
Abstract
Germination and physical field treatments are processing techniques that have been successfully used to change the amount of active ingredients in flaxseed. However, it is unknown if they work synergistically. This study investigated the effect of microwave-assisted germination on the lignan concentration and [...] Read more.
Germination and physical field treatments are processing techniques that have been successfully used to change the amount of active ingredients in flaxseed. However, it is unknown if they work synergistically. This study investigated the effect of microwave-assisted germination on the lignan concentration and antioxidant activity of several flaxseed tissue components. Lignans were primarily dispersed in the flaxseed seed coat. Microwave treatment and germination significantly affected the levels of lignans in various flaxseed sections. Flaxseed hulls’ lignan content and antioxidant activity could be increased by microwave treatment (130 W for 14 s) after germination of 0, 48, or 96 h. Flaxseed kernels lignan content and antioxidant activity could be increased by microwave treatment (130 W for 10 s) before germination. Whole flaxseeds could be improved by microwave treatment (130 W for 10 s) after germination for 72 h. The findings provided a theoretical basis for reducing the loss of lignan resources in flaxseed, enhancing its use as a functional food ingredient, and clarifying the targeted utilization of various lignan sources. Full article
(This article belongs to the Special Issue Oils and Fats: Structure and Stability)
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19 pages, 584 KiB  
Review
Incorporation of E-Waste Plastics into Asphalt: A Review of the Materials, Methods, and Impacts
by Sepehr Mohammadi, Dongzhao Jin, Zhongda Liu and Zhanping You
Encyclopedia 2025, 5(3), 112; https://doi.org/10.3390/encyclopedia5030112 (registering DOI) - 1 Aug 2025
Viewed by 19
Abstract
This paper presents a comprehensive review of the environmentally friendly management and reutilization of electronic waste (e-waste) plastics in flexible pavement construction. The discussion begins with an overview of e-waste management challenges and outlines key recycling approaches for converting plastic waste into asphalt-compatible [...] Read more.
This paper presents a comprehensive review of the environmentally friendly management and reutilization of electronic waste (e-waste) plastics in flexible pavement construction. The discussion begins with an overview of e-waste management challenges and outlines key recycling approaches for converting plastic waste into asphalt-compatible materials. This review then discusses the types of e-waste plastics used for asphalt modification, their incorporation methods, and compatibility challenges. Physical and chemical treatment techniques, including the use of free radical initiators, are then explored for improving dispersion and performance. Additionally, in situations where advanced pretreatment methods are not applicable due to cost, safety, or technical constraints, the application of alternative approaches, such as the use of low-cost complementary additives, is discussed as a practical solution to enhance compatibility and performance. Finally, the influence of e-waste plastics on the conventional and rheological properties of asphalt binders, as well as the performance of asphalt mixtures, is also evaluated. Findings indicate that e-waste plastics, when combined with appropriate pretreatment methods and complementary additives, can enhance workability, cold-weather cracking resistance, high-temperature anti-rutting performance, and resistance against moisture-induced damage while also offering environmental and economic benefits. This review highlights the potential of e-waste plastics as sustainable asphalt modifiers and provides insights across the full utilization pathway, from recovery to in-field performance. Full article
(This article belongs to the Collection Sustainable Ground and Air Transportation)
22 pages, 5123 KiB  
Article
Tailored Effects of Plasma-Activated Water on Hair Structure Through Comparative Analysis of Nitrate-Rich and Peroxide-Rich Formulations Across Different Hair Types
by Antonia de Souza Leal, Michaela Shiotani Marcondes, Ariane Leite, Douglas Leite, Clodomiro Alves Junior, Laurita dos Santos and Rodrigo Pessoa
Appl. Sci. 2025, 15(15), 8573; https://doi.org/10.3390/app15158573 (registering DOI) - 1 Aug 2025
Viewed by 27
Abstract
Plasma-activated water (PAW), enriched with reactive oxygen and nitrogen species (RONS), presents oxidative and antimicrobial characteristics with potential in cosmetic applications. This study examined the effects of two PAW formulations—nitrate-rich (PAW-N) and peroxide-rich (PAW-P)—on human hair types classified as straight (Type 1), wavy [...] Read more.
Plasma-activated water (PAW), enriched with reactive oxygen and nitrogen species (RONS), presents oxidative and antimicrobial characteristics with potential in cosmetic applications. This study examined the effects of two PAW formulations—nitrate-rich (PAW-N) and peroxide-rich (PAW-P)—on human hair types classified as straight (Type 1), wavy (Type 2), and coily/kinky (Type 4). The impact of PAW on hair structure and chemistry was evaluated using Fourier-transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), UV–Vis spectrophotometry, and physicochemical analyses of the liquids (pH, ORP, conductivity, and TDS). PAW-N, with high nitrate content (~500 mg/L), low pH (2.15), and elevated conductivity (6244 µS/cm), induced significant damage to porous hair types, including disulfide bond cleavage, protein oxidation, and lipid degradation, as indicated by FTIR and EDS data. SEM confirmed severe cuticle disruption. In contrast, PAW-P, containing >25 mg/L of hydrogen peroxide and exhibiting milder acidity and lower ionic strength, caused more localized and controlled oxidation with minimal morphological damage. Straight hair showed greater resistance to both treatments, while coily and wavy hair were more susceptible, particularly to PAW-N. These findings suggest that the formulation and ionic profile of PAW should be matched to hair porosity for safe oxidative treatments, supporting the use of PAW-P as a gentler alternative in hair care technologies. Full article
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33 pages, 2639 KiB  
Article
Functional and Safety Profile of Limosilactobacillus vaginalis and Development of Oral Fast-Disintegrating Tablets for Gut Microbiota Modulation
by Barbara Giordani, Federica Monti, Elisa Corazza, Sofia Gasperini, Carola Parolin, Angela Abruzzo, Claudio Foschi, Antonella Marangoni, Monia Lenzi, Barbara Luppi and Beatrice Vitali
Pharmaceutics 2025, 17(8), 1011; https://doi.org/10.3390/pharmaceutics17081011 (registering DOI) - 1 Aug 2025
Viewed by 24
Abstract
Background/Objectives: Early gut colonization by bifidobacteria, occurring more favorably in vaginally born infants than in those delivered via C-section, is crucial for maintaining overall health. The study investigated the health-promoting properties of Limosilactobacillus vaginalis BC17 both as viable cells and as postbiotics [...] Read more.
Background/Objectives: Early gut colonization by bifidobacteria, occurring more favorably in vaginally born infants than in those delivered via C-section, is crucial for maintaining overall health. The study investigated the health-promoting properties of Limosilactobacillus vaginalis BC17 both as viable cells and as postbiotics (i.e., cell-free supernatant and heat-killed cells), with the purpose of developing oral formulations to support intestinal health. Methods: The safety, effects on the adhesion of bifidobacteria and enteropathogens to intestinal cells, and anti-inflammatory properties of L. vaginalis BC17 viable cells and postbiotics were evaluated. Fast-disintegrating tablets were formulated by freeze-drying cell-free supernatant in combination with heat-killed or viable cells alongside maltodextrins. Results: The formulations were shown to be non-genotoxic and compatible with intestinal cell lines (Caco-2 and HT-29). BC17 viable cells survived in co-culture with intestinal cells up to 48 h and exhibited moderate adhesion to the cell lines. Notably, both BC17 viable cells and postbiotics enhanced the adhesion of beneficial bifidobacteria to Caco-2 cells by up to 250%, while reducing enteropathogens adhesion by 40–70%. Moreover, they exerted significant anti-inflammatory effects, reducing nitric oxide production in macrophages by 40–50% and protecting intestinal cells from SDS-induced damage. The formulations allowed administration of at least 109 BC17 cells in infants and adults through easy and rapid dispersion in milk or water, or directly in the oral cavity without chewing, and preserved their functional properties for up to 3 months of storage. Conclusions: L. vaginalis BC17 viable cells and postbiotics, as well as fast-disintegrating tablets, showed promising functional and safety profiles. Although further in vivo validation is needed, this approach represents a compelling strategy for promoting gut health. Full article
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16 pages, 2578 KiB  
Article
Experimental Comparison Between Two-Course Masonry Specimens and Three-Course Extracted Masonry Specimens in Clay Masonry Structures
by Bernardo Tutikian and Felipe Schneider
Processes 2025, 13(8), 2446; https://doi.org/10.3390/pr13082446 (registering DOI) - 1 Aug 2025
Viewed by 27
Abstract
This study investigates the relationship between the compressive strength of two-course masonry specimens and three-course masonry specimens extracted from previously constructed walls, to correlate the execution control specimens with the retest specimens. Compressive strength tests were performed on clay masonry units, laboratory-built two-course [...] Read more.
This study investigates the relationship between the compressive strength of two-course masonry specimens and three-course masonry specimens extracted from previously constructed walls, to correlate the execution control specimens with the retest specimens. Compressive strength tests were performed on clay masonry units, laboratory-built two-course masonry specimens, and three-course masonry specimens extracted from constructed walls, following the prescriptions of NBR 15270 and NBR 16868-3. The results demonstrate that three-course masonry specimens exhibit lower compressive strength (characteristic and average, 44.83% and 40.29%, respectively) compared to two-course masonry specimens. Additionally, it was found that the dispersion of results is greater in three-course masonry specimens. Given that three-course specimens are typically used when it becomes necessary to verify the structural compliance of executed masonry—usually following unsatisfactory results from execution control using two-course specimens—more data are needed to compare such results. Factors such as increased height-to-thickness ratio, the presence of head joints, and the influence of execution conditions at the construction site seem to influence the difference between two and three-course specimens, as well as the dispersion of the results. Therefore, it is essential that technical standards provide supporting criteria to enable a reliable comparison between two-course specimens used for execution control and three-course specimens used as retest elements. Full article
(This article belongs to the Special Issue Composite Materials Processing, Modeling and Simulation)
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22 pages, 1287 KiB  
Article
Comparative Analysis of the Gardner Equation in Plasma Physics Using Analytical and Neural Network Methods
by Zain Majeed, Adil Jhangeer, F. M. Mahomed, Hassan Almusawa and F. D. Zaman
Symmetry 2025, 17(8), 1218; https://doi.org/10.3390/sym17081218 (registering DOI) - 1 Aug 2025
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Abstract
In the present paper, a mathematical analysis of the Gardner equation with varying coefficients has been performed to give a more realistic model of physical phenomena, especially in regards to plasma physics. First, a Lie symmetry analysis was carried out, as a result [...] Read more.
In the present paper, a mathematical analysis of the Gardner equation with varying coefficients has been performed to give a more realistic model of physical phenomena, especially in regards to plasma physics. First, a Lie symmetry analysis was carried out, as a result of which a symmetry classification following the different representations of the variable coefficients was systematically derived. The reduced ordinary differential equation obtained is solved using the power-series method and solutions to the equation are represented graphically to give an idea of their dynamical behavior. Moreover, a fully connected neural network has been included as an efficient computation method to deal with the complexity of the reduced equation, by using traveling-wave transformation. The validity and correctness of the solutions provided by the neural networks have been rigorously tested and the solutions provided by the neural networks have been thoroughly compared with those generated by the Runge–Kutta method, which is a conventional and well-recognized numerical method. The impact of a variation in the loss function of different coefficients has also been discussed, and it has also been found that the dispersive coefficient affects the convergence rate of the loss contribution considerably compared to the other coefficients. The results of the current work can be used to improve knowledge on the nonlinear dynamics of waves in plasma physics. They also show how efficient it is to combine the approaches, which consists in the use of analytical and semi-analytical methods and methods based on neural networks, to solve nonlinear differential equations with variable coefficients of a complex nature. Full article
(This article belongs to the Section Physics)
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