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27 pages, 9637 KB  
Article
ConvNeXt-L-Based Recognition of Decorative Patterns in Historical Architecture: A Case Study of Macau
by Junling Zhou, Lingfeng Xie, Pia Fricker and Kuan Liu
Buildings 2025, 15(20), 3705; https://doi.org/10.3390/buildings15203705 - 14 Oct 2025
Abstract
As a well-known World Cultural Heritage Site, the Historic Centre of Macao’s historical buildings possess a wealth of decorative patterns. These patterns contain cultural esthetics, geographical environment, cultural traditions, and other elements from specific historical periods, deeply reflecting the evolution of religious rituals [...] Read more.
As a well-known World Cultural Heritage Site, the Historic Centre of Macao’s historical buildings possess a wealth of decorative patterns. These patterns contain cultural esthetics, geographical environment, cultural traditions, and other elements from specific historical periods, deeply reflecting the evolution of religious rituals and political and economic systems throughout history. Through long-term research, this article constructs a dataset of 11,807 images of local decorative patterns of historical buildings in Macau, and proposes a fine-grained image classification method using the ConvNeXt-L model. The ConvNeXt-L model is an efficient convolutional neural network that has demonstrated excellent performance in image classification tasks in fields such as medicine and architecture. Its outstanding advantages lie in limited training samples, diverse image features, and complex scenes. The most typical advantage of this model is its structural integration of key design concepts from a Transformer, which significantly enhances the feature extraction and generalization ability of samples. In response to the objective reality that the decorative patterns of historical buildings in Macau have rich levels of detail and a limited number of functional building categories, ConvNeXt-L maximizes its ability to recognize and classify patterns while ensuring computational efficiency. This provides a more ideal technical path for the classification of small-sample complex images. This article constructs a deep learning system based on the PyTorch 1.11 framework and compares ResNet50, EfficientNet-B7, ViT-B/16, Swin-B, RegNet-Y-16GF, and ConvNeXt series models. The results indicate a positive correlation between model performance and structural complexity, with ConvNeXt-L being the most ideal in terms of accuracy in decorative pattern classification, due to its fusion of convolution and attention mechanisms. This study not only provides a multidimensional exploration for the protection and revitalization of Macao’s historical and cultural heritage and enriches theoretical support and practical foundations but also provides new research paths and methodological support for artificial intelligence technology to assist in the planning and decision-making of historical urban areas. Full article
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47 pages, 14696 KB  
Article
Wrapping Matters: Unpacking the Materiality of Votive Animal Mummies
by Maria Diletta Pubblico
Heritage 2025, 8(10), 415; https://doi.org/10.3390/heritage8100415 - 3 Oct 2025
Viewed by 274
Abstract
This study presents the first systematic investigation of ancient Egyptian votive animal mummy wrappings, based on the analysis of an extensive dataset encompassing specimens from various museum collections and archaeological contexts. The research addresses the long-standing neglect and fragmented understanding of the wrapping [...] Read more.
This study presents the first systematic investigation of ancient Egyptian votive animal mummy wrappings, based on the analysis of an extensive dataset encompassing specimens from various museum collections and archaeological contexts. The research addresses the long-standing neglect and fragmented understanding of the wrapping chaîne opératoire and aims to establish a consistent terminology, as the different stages of the wrapping sequence, bundle shapes, and decorative patterns have often been described vaguely. Through an interdisciplinary methodology that integrates photogrammetry, colorant identification, textile analysis, and experimental archaeology, the study explores the complexity of wrapping practices across their different stages. This approach offers new insights into the structural logic, raw material selection, and design conventions behind this production. The analysis reveals that the bundles exhibit standardized shapes and decorative patterns grounded in well-established visual criteria and manufacturing sequences. These findings demonstrate that the wrappings reflect a codified visual language and a high level of technical knowledge, deeply rooted in Egyptian tradition. The study also emphasizes its economic implications: the wrapping significantly enhanced the perceived value of the offering, becoming the primary element influencing both its material and symbolic worth. Ultimately, this work provides an interpretative framework for understanding wrapping as an essential medium of ritual sacralization for votive animal mummies, allowing the individual prayer to be effectively conveyed to the intended deity. Consequently, this research marks a significant step forward in advancing the technical, aesthetic, and ritual insight of wrapping practices, which preserve a wealth of still-overlooked information. Full article
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27 pages, 14407 KB  
Article
Exploring Factors Behind Weekday and Weekend Variations in Public Space Vitality in Traditional Villages, Using Wi-Fi Sensing Method
by Sheng Liu, Zhenni Zhu, Yichen Gao, Shanshan Wang and Yanchi Zhou
ISPRS Int. J. Geo-Inf. 2025, 14(10), 386; https://doi.org/10.3390/ijgi14100386 - 2 Oct 2025
Viewed by 406
Abstract
With the rise in rural tourism, public space use has become more complex, causing significant weekday-weekend vitality imbalances. However, the factors shaping these dynamics in traditional villages remain unclear. This study uses Wi-Fi sensing method to analyze vitality variations across weekdays and weekends, [...] Read more.
With the rise in rural tourism, public space use has become more complex, causing significant weekday-weekend vitality imbalances. However, the factors shaping these dynamics in traditional villages remain unclear. This study uses Wi-Fi sensing method to analyze vitality variations across weekdays and weekends, and it develops a 13-metric evaluation framework to examine how built environment factors, from both internal and external dimensions, differentially influence the vitality of public spaces in traditional villages across various time periods. Using 17 public spaces in Yantou Village, Lishui, China, as a case, it finds: (1) Historical Element Proximity consistently and significantly drives public space vitality across all periods; (2) Leisure Facility Count and Decorative Element Count demonstrate strong positive effects during weekend morning peaks. (3) Retail Facility Count significantly reduces vitality during weekend morning peak but enhances it during midday off-peak, whereas Street Vendor Count shows the opposite pattern—increasing vitality in morning peak and decreasing it in midday off-peak. Using Wi-Fi sensing’s high-resolution, real-time, and non-invasive capabilities, this study provides a scientific method to accurately assess the variations in public space vitality and their impact factors between weekdays and weekends in traditional villages, offering technical support for enhancing public space vitality and sustainably revitalizing rural heritage. Full article
(This article belongs to the Special Issue Spatial Information for Improved Living Spaces)
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21 pages, 1382 KB  
Article
Formulation and Comparative Characterization of SLNs and NLCs for Targeted Co-Delivery of Paclitaxel and Hydroxytyrosol Carboxylic Acid Esters Against Triple-Negative Breast Cancer
by Elena Peira, Simona Sapino, Daniela Chirio, Fabio Bucciol, Flavia Turku, Emanuela Calcio Gaudino, Giancarlo Cravotto, Chiara Riganti and Marina Gallarate
Pharmaceutics 2025, 17(9), 1208; https://doi.org/10.3390/pharmaceutics17091208 - 16 Sep 2025
Viewed by 507
Abstract
Background: The management of triple-negative breast cancer (TNBC) remains a therapeutic challenge due to the presence of multidrug resistance (MDR) and hypoxia-induced chemoresistance, both of which substantially reduce the efficacy of conventional chemotherapy. Although certain natural compounds have shown the ability to modulate [...] Read more.
Background: The management of triple-negative breast cancer (TNBC) remains a therapeutic challenge due to the presence of multidrug resistance (MDR) and hypoxia-induced chemoresistance, both of which substantially reduce the efficacy of conventional chemotherapy. Although certain natural compounds have shown the ability to modulate these resistance mechanisms, their clinical application is hindered by poor solubility and limited bioavailability. Among such phenolic compounds, 7-hydroxytyrosol (HTyr)—a phenolic compound from olive oil and olive leaves—has been reported to modulate hypoxia-inducible factor-1 (HIF-1). Methods: In this study, we developed hyaluronic acid (HA)-decorated solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) for the targeted and synergistic co-delivery of paclitaxel (PTX) and hydroxytyrosol carboxylic acid esters (Cn-HTyrCA), precursors that share the antioxidant biphenolic moiety with HTyr. Results: Among the formulations tested, SLNs of trilaurin (TL) exhibited the highest entrapment efficiency (EE%), optimal average particle size, Zeta potential, and good colloidal stability. Of the synthesized Cn-HTyrCA derivatives, C8- and C10-HTyrCA showed superior loading capacity. In vitro release profiles indicated a sustained drug release pattern for both nanoparticles. HA decoration led to a marked increase in particle size and induced a shift in surface charge, confirming successful decoration and suggesting enhanced targeting potential via HA-CD44 interaction. Cytotoxicity assays conducted on MDA-MB-231 cells showed that PTX-loaded TL-SLNs exerted enhanced antitumor activity, particularly when HA-decorated, and a synergistic effect was observed upon co-administration with SLNs loaded with C8-HTyrCA. Conclusions: Overall, our findings support the potential of SLN as a promising strategy to overcome key resistance mechanisms in TNBC, enabling reduced chemotherapeutic dosing and improving therapeutic outcomes. Full article
(This article belongs to the Section Drug Delivery and Controlled Release)
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21 pages, 14400 KB  
Article
The Decorative Art and Evolution of the “Xuan” in Ancestral Halls of Southern Anhui
by Yilun Fan, Jun Cai and Liwen Jiang
Buildings 2025, 15(18), 3294; https://doi.org/10.3390/buildings15183294 - 12 Sep 2025
Viewed by 508
Abstract
Numerous well-preserved ancestral halls dating back to the Ming and Qing dynasties are found throughout Southern Anhui, China. Among the architectural elements in these ancestral halls, the “Xuan” plays a significant decorative role. Nevertheless, scholarly research on the “Xuan” in this region remains [...] Read more.
Numerous well-preserved ancestral halls dating back to the Ming and Qing dynasties are found throughout Southern Anhui, China. Among the architectural elements in these ancestral halls, the “Xuan” plays a significant decorative role. Nevertheless, scholarly research on the “Xuan” in this region remains limited, particularly in the context of the temporal and regional evolution of its decorative art. This study examines the decorative characteristics and spatiotemporal evolution of the front Xuan of 115 ancestral halls across Southern Anhui belonging to the Ming and Qing periods. Using field surveys, a combination of qualitative and quantitative analyses, and ArcGIS kernel density analysis, this study identifies key trends in Xuan evolution. Specifically, the findings indicate that the Chuanpeng Xuan emerged as the predominant style, replacing the earlier Renzi Xuan after the mid-Ming period. By the late Qing period, the primary structural components of the Xuan showed increasing standardization, while accessory elements showed notable diversification. During the commercial boom of the mid-Qing era, flood-dragon carvings and S-shaped short beams became especially prevalent. Spatially, kernel density analysis demonstrated a core-periphery distribution pattern: mainstream styles were concentrated in central counties, whereas a greater variety of stylistic combinations and niche forms emerged in border regions. These evolutionary patterns reflect the broader sociohistorical dynamics of this period, including ritual reforms during the Ming dynasty, the patronage of Huizhou merchants, innovations in carving tools, and wartime resource constraints. These findings provide diagnostic criteria for dating unidentified ancestral halls and offer a practical reference for the conservation of architectural heritage. Full article
(This article belongs to the Section Architectural Design, Urban Science, and Real Estate)
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26 pages, 5226 KB  
Article
Architectural Semiotics Unveiled: Parallel Investigations into Visual Processing Mechanisms and Cognitive Discrepancies of She Ethnic Motifs
by Peiyan Du, Tongyan Li, Ye Chen and Jingyu Chen
Buildings 2025, 15(17), 3123; https://doi.org/10.3390/buildings15173123 - 1 Sep 2025
Viewed by 801
Abstract
As an essential medium for the cultural narrative of architectural space, studying the cognitive transformation mechanisms of traditional ethnic decorative patterns is critical for their effective preservation and innovative application. This research focuses on typical decorative motifs found in She ethnic architectural heritage, [...] Read more.
As an essential medium for the cultural narrative of architectural space, studying the cognitive transformation mechanisms of traditional ethnic decorative patterns is critical for their effective preservation and innovative application. This research focuses on typical decorative motifs found in She ethnic architectural heritage, systematically classifying them into five categories—animal, plant, human figure, totem, and geometric—based on symbolic themes, formal structure, and cultural function. Correspondingly, 20 sets of standardized black-and-white line drawing stimuli were developed for experimental use. Methodologically, this study utilized the EyeLink 1000 eye-tracking system to acquire real-time gaze metrics, including fixation duration and saccadic amplitude, as well as pupil dilation responses from participants engaged in a controlled pattern observation task. Immediately after observation, participants completed a semantic differential assessment using a five-point Likert scale. Data analysis employed descriptive statistics, analysis of variance (ANOVA), Kruskal–Wallis tests, and Bonferroni-adjusted post hoc comparisons (α = 0.05). Attention allocation was further examined through heatmaps and gaze trajectory visualizations to provide comprehensive insight into visual engagement. Two principal findings were identified: first, male participants showed a predominant focus on holistic structural composition and cultural symbol representation, whereas female participants exhibited a processing bias towards fine details; second, concrete symbols imbued with historical significance elicited more pronounced emotional responses, while abstract geometric patterns necessitated formal reconstruction to enhance cognitive accessibility. These findings offer empirical support for gender-inclusive architectural design strategies and inform practical approaches for safeguarding cultural heritage within contemporary architectural environments. Consequently, modern reinterpretation of traditional decorative patterns should balance cultural narrative fidelity with functional adaptation, achieving inclusive expression through contextual reconstruction and interactive design strategies. Future research directions include expanding participant demographics to encompass cross-cultural cohorts and incorporating multimodal neuroimaging techniques to elucidate the underlying cognitive and affective mechanisms, thereby advancing the sustainable transmission and innovation of ethnic cultural heritage. Full article
(This article belongs to the Section Architectural Design, Urban Science, and Real Estate)
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26 pages, 4349 KB  
Article
Palazzo Farnese and Dong’s Fortified Compound: An Art-Anthropological Cross-Cultural Analysis of Architectural Form, Symbolic Ornamentation, and Public Perception
by Liyue Wu, Qinchuan Zhan, Yanjun Li and Chen Chen
Buildings 2025, 15(15), 2720; https://doi.org/10.3390/buildings15152720 - 1 Aug 2025
Viewed by 538
Abstract
This study presents a cross-cultural comparison of two fortified residences—Palazzo Farnese in Italy and Dong’s Fortified Compound in China—through a triadic analytical framework encompassing architectural form, symbolic ornamentation, and public perception. By combining field observation, iconographic interpretation, and digital ethnography, the research investigates [...] Read more.
This study presents a cross-cultural comparison of two fortified residences—Palazzo Farnese in Italy and Dong’s Fortified Compound in China—through a triadic analytical framework encompassing architectural form, symbolic ornamentation, and public perception. By combining field observation, iconographic interpretation, and digital ethnography, the research investigates how heritage meaning is constructed, encoded, and reinterpreted across distinct sociocultural contexts. Empirical materials include architectural documentation, decorative analysis, and a curated dataset of 4947 user-generated images and 1467 textual comments collected from Chinese and international platforms between 2020 and 2024. Methods such as CLIP-based visual clustering and BERTopic-enabled sentiment modelling were applied to extract patterns of perception and symbolic emphasis. The findings reveal contrasting representational logics: Palazzo Farnese encodes dynastic authority and Renaissance cosmology through geometric order and immersive frescoes, while Dong’s Compound conveys Confucian ethics and frontier identity via nested courtyards and traditional ornamentation. Digital responses diverge accordingly: international users highlight formal aesthetics and photogenic elements; Chinese users engage with symbolic motifs, family memory, and ritual significance. This study illustrates how historically fortified residences are reinterpreted through culturally specific digital practices, offering an interdisciplinary approach that bridges architectural history, symbolic analysis, and digital heritage studies. Full article
(This article belongs to the Section Architectural Design, Urban Science, and Real Estate)
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12 pages, 2191 KB  
Article
A Structural Colored Epoxy Resin Sensor for the Discrimination of Methanol and Ethanol
by Yongxing Guo, Yingying Yi, Limin Wu, Wei Liu, Yi Li and Yonggang Yang
Chemistry 2025, 7(4), 122; https://doi.org/10.3390/chemistry7040122 - 30 Jul 2025
Viewed by 604
Abstract
A thermochromic cholesteric liquid crystal (CLC) mixture was prepared using epoxies. The structural color of the CLCN film was tuned by changing the concentration of a chiral dopant and the polymerization temperature. It was found the yellow CLCN film can be used as [...] Read more.
A thermochromic cholesteric liquid crystal (CLC) mixture was prepared using epoxies. The structural color of the CLCN film was tuned by changing the concentration of a chiral dopant and the polymerization temperature. It was found the yellow CLCN film can be used as a sensor for the discrimination of methanol and ethanol which was proposed to be driven by the difference between the solubility parameters. Moreover, a colorful pattern was prepared based on the thermochromic property of the CLC mixture, which could be applied for decoration and as a sensor for chloroform. Full article
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81 pages, 10454 KB  
Review
Glancing Angle Deposition in Gas Sensing: Bridging Morphological Innovations and Sensor Performances
by Shivam Singh, Kenneth Christopher Stiwinter, Jitendra Pratap Singh and Yiping Zhao
Nanomaterials 2025, 15(14), 1136; https://doi.org/10.3390/nano15141136 - 21 Jul 2025
Cited by 1 | Viewed by 1237
Abstract
Glancing Angle Deposition (GLAD) has emerged as a versatile and powerful nanofabrication technique for developing next-generation gas sensors by enabling precise control over nanostructure geometry, porosity, and material composition. Through dynamic substrate tilting and rotation, GLAD facilitates the fabrication of highly porous, anisotropic [...] Read more.
Glancing Angle Deposition (GLAD) has emerged as a versatile and powerful nanofabrication technique for developing next-generation gas sensors by enabling precise control over nanostructure geometry, porosity, and material composition. Through dynamic substrate tilting and rotation, GLAD facilitates the fabrication of highly porous, anisotropic nanostructures, such as aligned, tilted, zigzag, helical, and multilayered nanorods, with tunable surface area and diffusion pathways optimized for gas detection. This review provides a comprehensive synthesis of recent advances in GLAD-based gas sensor design, focusing on how structural engineering and material integration converge to enhance sensor performance. Key materials strategies include the construction of heterojunctions and core–shell architectures, controlled doping, and nanoparticle decoration using noble metals or metal oxides to amplify charge transfer, catalytic activity, and redox responsiveness. GLAD-fabricated nanostructures have been effectively deployed across multiple gas sensing modalities, including resistive, capacitive, piezoelectric, and optical platforms, where their high aspect ratios, tailored porosity, and defect-rich surfaces facilitate enhanced gas adsorption kinetics and efficient signal transduction. These devices exhibit high sensitivity and selectivity toward a range of analytes, including NO2, CO, H2S, and volatile organic compounds (VOCs), with detection limits often reaching the parts-per-billion level. Emerging innovations, such as photo-assisted sensing and integration with artificial intelligence for data analysis and pattern recognition, further extend the capabilities of GLAD-based systems for multifunctional, real-time, and adaptive sensing. Finally, current challenges and future research directions are discussed, emphasizing the promise of GLAD as a scalable platform for next-generation gas sensing technologies. Full article
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26 pages, 9909 KB  
Article
Three-Tiered Defensive System and Ethnic Fusion: A Study of Architectural Art in Guomari Fortress, Eastern Qinghai
by Liyue Wu, Qinchuan Zhan and Yanjun Li
Buildings 2025, 15(13), 2218; https://doi.org/10.3390/buildings15132218 - 24 Jun 2025
Cited by 1 | Viewed by 808
Abstract
Guomari fortress in eastern Qinghai Province exemplifies vernacular architecture shaped by multiethnic interaction, environmental adaptation, and localized defense strategies. Originally a Ming Dynasty military-agricultural outpost, it evolved into a Tu ethnic settlement. Fieldwork, including architectural surveys and spatial analysis, identified a three-tiered defensive [...] Read more.
Guomari fortress in eastern Qinghai Province exemplifies vernacular architecture shaped by multiethnic interaction, environmental adaptation, and localized defense strategies. Originally a Ming Dynasty military-agricultural outpost, it evolved into a Tu ethnic settlement. Fieldwork, including architectural surveys and spatial analysis, identified a three-tiered defensive system: (1) strategic use of terrain and rammed-earth walls; (2) labyrinthine alleys with L-, T-, and cross-shaped intersections; and (3) interconnected rooftops forming elevated circulation routes. Courtyards are categorized into single-line, L-shaped, U-shaped, and fully enclosed layouts, reflecting adaptations to terrain, ritual functions, and thermal needs. Architectural features such as thick loam-coated walls and flat roofs demonstrate climatic adaptation, while the integration of Han timber frameworks, Tibetan prayer halls, and Tu decorative elements reveals cultural convergence. Traditional craftsmanship, including carved wooden scripture blocks and tsampa-based murals, is embedded within domestic and ritual spaces. The fortress’s circulation patterns mirror Tibetan Buddhist cosmology, with mandala-like alleys and rooftop circumambulation routes. These findings offer insights into vernacular resilience and inform conservation strategies for multiethnic fortified settlements. Full article
(This article belongs to the Section Building Materials, and Repair & Renovation)
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12 pages, 1967 KB  
Article
Cholesteric Liquid Crystal Polymer Network Patterns with a Golden Structural Color
by Qingyan Zeng, Wei Liu, Yi Li and Yonggang Yang
Chemistry 2025, 7(3), 93; https://doi.org/10.3390/chemistry7030093 - 3 Jun 2025
Viewed by 1227
Abstract
Cholesteric liquid crystal polymer network (CLCN) films with composite structural colors have potential applications in decoration and anti-counterfeiting. Herein, a thermochromic acrylate-based cholesteric liquid crystal mixture was prepared. The structural color of CLCN films can be controlled by the photopolymerization temperature. Based on [...] Read more.
Cholesteric liquid crystal polymer network (CLCN) films with composite structural colors have potential applications in decoration and anti-counterfeiting. Herein, a thermochromic acrylate-based cholesteric liquid crystal mixture was prepared. The structural color of CLCN films can be controlled by the photopolymerization temperature. Based on the oxygen inhibition of the acrylate group, CLCN films with double reflection bands were prepared using a two-step photopolymerization method. The distance between these two reflection bands was controlled by the polymerization temperatures of these two steps. Since golden colors are the most attractive for decoration, herein, colorful patterns with a golden structural color were prepared by controlling the polymerization temperatures. Full article
(This article belongs to the Section Supramolecular Chemistry)
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14 pages, 4750 KB  
Review
The Development Potential of Spalted Wood Artifacts in China—An Analysis
by Chen Li and Seri C. Robinson
Colorants 2025, 4(2), 19; https://doi.org/10.3390/colorants4020019 - 3 Jun 2025
Viewed by 1050
Abstract
Spalted wood is a natural material characterized by distinctive colors and patterns from wood decay fungi as they digest their substrate and leave behind colored secretions. As an art form, spalted wood was used heavily in western Europe from the 1400s–1600s; however, its [...] Read more.
Spalted wood is a natural material characterized by distinctive colors and patterns from wood decay fungi as they digest their substrate and leave behind colored secretions. As an art form, spalted wood was used heavily in western Europe from the 1400s–1600s; however, its use in other parts of the world remains deeply understudied, even in cultures where wood played a dominant social role. The use of spalted wood in China, in particular, is unknown, despite a growing interest by Chinese researchers in modern spalting practices and their potential commercial value. This study systematically reviews the potential historic use, current artistic value, environmental significance, and future application prospects of spalted wood for a Chinese market. By integrating historical records, modern scientific research, and insights from traditional Chinese woodworking, the study provides a comprehensive analysis of the aesthetic and functional value of spalted wood for Chinese markets. The findings indicate that the random and non-reproducible nature of spalted wood imbues it with exceptional artistic appeal and collectability, which has a strong potential to appeal to Chinese furniture design, decorative arts, and high-end interior applications. Furthermore, spalted wood demonstrates considerable potential for resource recycling by turning otherwise non-commercial, pale, white woods into higher value options—a phenomenon that has been studied across Europe and North America. In China, this has the potential to reduce wood waste and advance ecological design. However, challenges remain in fungal infection control, processing techniques, and market adoption. With ongoing advancements in biotechnology and manufacturing processes, spalted wood is poised to gain greater recognition in Chinese art, design, and cultural innovation while also contributing to green manufacturing and sustainable development. Full article
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13 pages, 2245 KB  
Article
Mouse SPAG6L, a Key Cytoskeleton Modulator Essential for Male Germ Cell Development, Is Not Required for Sertoli Cell Function
by Tao Li, Wei Li, Cheng Zheng, Jannette M. Dufour, William H. Walker, Shuiqiao Yuan and Zhibing Zhang
Cells 2025, 14(11), 783; https://doi.org/10.3390/cells14110783 - 26 May 2025
Viewed by 740
Abstract
Mouse sperm-associated antigen 6-like (SPAG6L) evolved from SPAG6, the mammalian ortholog of Chlamydomonas PF16, which is localized in the central apparatus of the motile cilia and is essential for ciliary motility. Even though the amino acid sequences of the two SPAG6 proteins are [...] Read more.
Mouse sperm-associated antigen 6-like (SPAG6L) evolved from SPAG6, the mammalian ortholog of Chlamydomonas PF16, which is localized in the central apparatus of the motile cilia and is essential for ciliary motility. Even though the amino acid sequences of the two SPAG6 proteins are highly similar, the two proteins have different biological expression patterns in vivo. No major phenotypes were discovered in the global Spag6 knockout mice. However, the global Spag6l knockout mice demonstrated multiple phenotypes in tissues with and without cilia. Since SPAG6L decorates microtubules and modulates cytoskeleton function, and Sertoli cells have a well-developed microtubule transport network, the potential function of SPAG6L in Sertoli cells was evaluated. The floxed Spag6l mice were crossed with Amh-Cre transgenic mice to inactivate the Spag6l gene specifically in Sertoli cells. Surprisingly, the fertility of the homozygous mutant males was not reduced. The testis size and sperm number and motility showed no significant difference to those of the control mice. Testicular histology also showed normal spermatogenesis. No significant changes were observed in the number of Sertoli cells and blood–testis barrier function. Our study showed that the inactivation of only Spag6l does not affect Sertoli cell function during the first 6 months of life. Full article
(This article belongs to the Special Issue Advances in Spermatogenesis)
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34 pages, 56833 KB  
Article
Wearable Arduino-Based Electronic Interactive Tattoo: A New Type of High-Tech Humanized Emotional Expression for Electronic Skin
by Chuanwen Luo, Yan Zhang, Juan Zhang, Linyuan Hui, Ruisi Qi, Yuxiang Han, Xiang Sun, Yifan Li, Yufei Wei, Yiwen Zhang, Haoying Sun, Ning Li and Bo Zhang
Sensors 2025, 25(7), 2153; https://doi.org/10.3390/s25072153 - 28 Mar 2025
Viewed by 1651
Abstract
Skin is the largest organ of the human body and holds the functions of sensing, protecting, and regulating. Since ancient times, people have decorated their skin by painting themselves, cutting, and using accessories to express their personality and aesthetic consciousness as a kind [...] Read more.
Skin is the largest organ of the human body and holds the functions of sensing, protecting, and regulating. Since ancient times, people have decorated their skin by painting themselves, cutting, and using accessories to express their personality and aesthetic consciousness as a kind of artistic expression, one that shows the development and change of aesthetic consciousness. However, there are concerns regarding the inconvenience, high time cost, and negative body perception with traditional tattoos. In addition, the trend of skin decoration has gradually withdrawn due to a lack of intelligent interaction. In response to these problems, we proposed a wearable electronic skin tattoo that offers a novel means of communication and emotional expression for individuals with communication impairments, WABEIT. The tattoo uses skin-friendly PDMS as the base material, combines multi-mode sensing components such as silver wire circuit, a programmable Surface-Mounted Device (SMD), a thin-film-pressure sensor, and a heart rate sensor, and combines the embedded development board Arduino Nano for intelligent interaction, forming a wearable electronic interactive tattoo capable of sensing the environment, human–computer interaction, and the changeable performance of intelligent perception. The sensor is also equipped with a mobile power supply to support portability. The advantages of WABEIT are as follows: first, it avoids the pain, allergy, and long production process of traditional tattoos. Second, the patterns can adapt to different needs and generate feedback for users, which can effectively express personal emotions. Thirdly, the facility of removal reduces social discrimination and occupational constraints, which is especially suitable for East Asia. Experimental results indicate that the device exhibits a high sensitivity in signal response, a wide variety of pattern changes, and reliable interactive capabilities. The study demonstrates that the proposed design philosophy and implementation strategy can be generalized to the interactive design of other wearable devices, thereby providing novel insights and methodologies for human–computer interaction, electronic devices, and sensor applications. Full article
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24 pages, 6503 KB  
Article
Research on the Innovative Application of Song Dynasty Boundary Painting in Interior Soft Decoration Design Based on AIGC
by Jingting Meng, Xingjia Fang, Jian Xu and Ziqi Zhang
Buildings 2025, 15(7), 1067; https://doi.org/10.3390/buildings15071067 - 26 Mar 2025
Cited by 1 | Viewed by 1374
Abstract
An analysis of the practice path and methodology system of Artificial Intelligence Generated Content (AIGC) technology has been conducted in the field of inheritance and innovation of boundary paintings from Song Dynasty. This paper aims to provide valuable reference and guidance for the [...] Read more.
An analysis of the practice path and methodology system of Artificial Intelligence Generated Content (AIGC) technology has been conducted in the field of inheritance and innovation of boundary paintings from Song Dynasty. This paper aims to provide valuable reference and guidance for the application of AI technology in Song Dynasty boundary painting (Song painting) in the interior decoration design, so as to promote the effective integration of traditional aesthetics and modern design concepts. Firstly, the natural processing language model is used to generate the index layer suitable for the indoor soft decoration style of Song paintings, and the Analytic Hierarchy Process weight classification is used to select the cue words of the generated image. Secondly, Midjourney is used to generate Song Dynasty style images for keywords. Finally, Stable Diffusion control model is used to transfer the style of Song painting elements to interior decoration design. AIGC technology can effectively generate images with the style of Song painting elements, and play a unique role in style transfer and pattern design. It provides an innovative path for the integration of traditional art and modern design, and provides a wealth of possibilities for the modern application of Song painting. AIGC technology has significant potential in the inheritance and innovation of Song painting, which can bring new ideas and methods for interior decoration design, and contribute to the wide application and innovative development of Song painting art in the field of modern design. Full article
(This article belongs to the Section Architectural Design, Urban Science, and Real Estate)
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