Search Results (134)

Canada played a pivotal role in the establishment of the International Criminal Court (ICC) and it was the first country in the world to incorporate the Rome Statute in its domestic law when it passed the Crimes Against Humanity and War Crimes Act (CAHWCA) on 24 June 2000. The CAHWCA allows the application of universal jurisdiction for the prosecution of those persons responsible for “atrocity crimes” who are present in Canada. Yet, Canada’s record for the prosecution and conviction of those who are responsible for “atrocity crimes” under CAHWCA is far from enviable. Rather than taking a leadership role in the prosecution of those responsible for “atrocity crimes,” Canada has avoided doing so. Thus far, Canada has prosecuted only two atrocity crimes cases under universal jurisdiction: R. v. Munyaneza 2009 QCCS 2201 [2009] QJ No 4913 conviction and the denial of its appeal in R. v. Munyaneza 2201. (Quebec Court of Appeal, 7 May 2014); and an acquittal in the R. v. Mungwarere (Superior Court of Ontario, 5 July 2013) case. This article will analyze the ratio decidendi in these two precedent-setting cases that rest on the credibility and trustworthiness of the testimonial evidence presented. It also considers other factors that militate against the criminal investigation and prosecution of those who are allegedly responsible for atrocity crimes. This raises the fundamental question of whether it will be possible to “end impunity for international crimes” and advance international justice when States, such as Canada, are failing to prosecute and convict those who are responsible for atrocity crimes through universal jurisdiction. It calls on States to allocate adequate funding for criminal investigations and prosecutions under universal jurisdiction and to develop more rigorous, detailed, and refined methods for gathering and adducing credible and trustworthy testimonial evidence for the prosecution of cases involving these serious international crimes. Full article

Fraud remains a critical and evolving challenge in telecommunications, costing the industry billions annually. In Mobile Virtual Network Operator (MVNO) environments, conventional supervised approaches are limited because fraud labels are scarce or delayed, and outgoing-call behavior is shaped by heterogeneous tariffs. Using a real-world MVNO dataset (9603 subscribers, 1.78 million outgoing CDRs), we derive payment-based segments and confirm statistically significant baseline differences via Kruskal–Wallis tests with Dunn post hoc pairwise comparisons and Benjamini–Hochberg correction. We propose a plan-aware calibration strategy setting interpretable thresholds using segment-wise empirical quantiles. Evaluation employs both operational metrics (activation rates and workload) and two label-free alert quality proxy metrics: multi-rule co-occurrence and activation stability (coefficient of variation). Compared to global calibration, segment-aware calibration reduces the dominant S4 rule activation (5.44% to 4.59% of user-hours) while increasing sensitivity to rare overnight patterns (F6: 0.0017% to 0.0137% of user-days). Experiments confirm improved alert quality, and the robustness of these findings is confirmed by sensitivity analysis across quantile levels and alternative segmentation schemes. Overall, segment-specific calibration yields a more balanced, interpretable, and operationally fair rule-based screening layer suitable for MVNO constraints. Full article

Methanogens, or methanogenic archaea (MA), are among the most ancient and widely distributed microorganisms, characterized by a unique metabolism that generates methane (CH₄) as the terminal product of anaerobic respiration. Their ability to grow and/or survive across a wide range of environmental conditions has made methanogens key contributors to biogeochemical cycles throughout most of Earth’s history. Most importantly, these oxygen-sensitive microorganisms have regulated the climate since the early Archean and impacted biogeochemical cycles throughout Earth’s history by producing the potent greenhouse gas, CH₄, while consuming H₂, CO₂, and small organic molecules. Hence, methanogens are attributed a key role in the start and end of several Proterozoic glaciations and mass extinction events. Their specific roles in the long-term carbon cycle that focus on CH₄ production are well-established, but, in contrast, only very few studies report on interactions with CaCO₃ and long-term carbon storage. Methanogens evolved early during Earth’s history, likely during the Archaean Eon, in layered benthic microbial communities called microbial mats. When lithified, these mats form microbialites that represent some of the earliest evidence of life in the fossil record, dating back >3.5 Gy. Methanogens are an integral part of contemporary microbial mats and have been identified both in the anoxic and oxic zones of these sedimentary ecosystems; however, their adaptations to apparently unfavorable oxic conditions and their role in the precipitation of carbonate in mats are unclear. In addition to an important role in the evolution of our planet by producing CH₄, methanogens may also produce a biosignature that could be relevant for astrobiology research. This review will discuss the diversity, physiology, and ecology of methanogens in detail to clarify their role in some of the major biogeochemical processes and ecological climatic events through the fluctuating environmental conditions on Earth through geologic time. Full article

Agent-based systems built on large language models (LLMs) increasingly rely on complex internal reasoning processes, tool interactions, and memory mechanisms. However, the internal decision-making dynamics of such agents remain difficult to observe, analyze, and compare in a systematic manner. To address this limitation, we present AgentSec, a curated dataset of structured agent interaction traces designed to support the analysis of agent-level reasoning and action behaviors. The dataset consists of 30 deterministic and non-redundant scenario instances, each capturing a complete agent interaction session under a fixed and validated schema. Quantitatively, the 30 released sessions comprise 67 decision nodes and 45 tool calls (73.3% successful), with provenance graphs exhibiting an average depth of 4.53 (max 7) and a maximum branching factor of 3. Scenarios are organized according to a predefined taxonomy of agent behavioral patterns, including tool success and failure modes, fallback strategies, memory conflicts and overwrites, decision rollbacks, and provenance branching structures. Each scenario encodes a distinct analytical case rather than a parametric variation, enabling focused and interpretable study of agent decision-making processes. AgentSec provides detailed records of decision traces, tool calls, memory updates, and provenance relations, and is intended to facilitate reproducible research on agent behavior analysis, auditing, and evaluation. The dataset is released alongside its schema, scenario manifest, and validation tooling to support reuse and extension by the research community. Rather than serving as a large-scale performance benchmark, AgentSec is explicitly designed as a diagnostic and unit-test suite for auditing agent-level reasoning logic and provenance consistency under controlled structural conditions. Full article

Background/Objectives: This study investigates the predictive role of pre-operative sonographic assessment of ovarian mobility in determining intra-operative ovarian resectability among patients undergoing vaginal hysterectomy for pelvic organ prolapse. Methods: This prospective study was conducted in a tertiary academic urogynecology center. Women with pelvic organ prolapse scheduled for vaginal hysterectomy were consecutively recruited after providing informed consent. Pre-operatively, all patients had a detailed history, pelvic examination (POP-Q), and pelvic floor ultrasound (including assessment of the mobility of both ovaries and sonographic determination of ovarian descent in relation to the pelvic ischial spines). Patients were planned for vaginal hysterectomy, anterior and posterior colporrhaphy, McCall culdoplasty, and bilateral salpingo-oophorectomy (SO), where feasible. During surgery, the location and mobility of the ovaries, as well as the presence of peri-ovarian adhesions, were recorded. Pair-to-pair comparisons between sonographic and clinical findings were performed. Results: From February 2023 to January 2024, 50 Caucasian adult women underwent reconstructive vaginal surgery for prolapse. Thirty-five patients underwent concomitant bilateral SO via vaginal route, seven underwent unilateral SO, and three under went salpingectomy only. ROC analysis indicated that pre-operative ultrasound assessment of ovarian mobility predicts: (1) intra-operative ovarian mobility (sensitivity 95.6%, specificity 77.8%); (2) the presence of peri-ovarian adhesions (sensitivity 46.1%, specificity 94.2%); and (3) resectability, i.e., the ability to perform SO via the vaginal route (sensitivity 96.4%, specificity 50.0%). The absence of ovarian mobility was not associated with an increased risk of intra-operative and post-operative complications. Conclusions: Pre-operative sonographic assessment of ovarian location and mobility can predict ovarian location and resectability during vaginal surgery with high diagnostic accuracy. Full article

Despite being the most popular sutra tableau in Dunhuang, the utter lack of any comprehensive, or chronological academic analysis even in Chinese calls for a thorough research on the Medicine Buddha Sutra iconography at Dunhuang. This paper will explore the Medicine Buddha both in the literary form, the sutras, and the visual form, the sutra tableaux, when they first appeared in China during the Sui Dynasty. First, the relevant sections of the four Medicine Buddha Sutra translated in Chinese will be examined in detail. Then, the earliest four pictorial representations, namely Caves 417, 433, 436, and 394 at Dunhuang, will be scrutinized to establish a firm foundation of this said sutra tableau for later periods. By comparing the deities, and other special attributes presented in these images with what were recorded in the sutras, this paper reveals how the anonymous monastics and artists “re-presented” the Medicine Buddha from literary form to pictorial form, which embodies the intermediallity during the Sui Dynasty in Dunhuang. After analyzing how the textual elements such as the Medicine Buddha, attendant Bodhisattvas, Twelve Demigods, Four Heavenly Kings, and the magical life-prolonging instruments were depicted in the paintings, intermediality between the texts and imagery is brought to light. Two most decisive details, the small sizes of the cartouches for the inscriptions of the Twelve Demigods, and the number of Medicine statues that should be present at the ritual, clearly show the Medicine Buddha Sutra imagery painted during the Sui Dynasty in Dunhuang is based on the earliest Chinese edition, Sutra on the Initiation to Remove Unwholesome Deeds and Attain Salvation from Birth and Death Taught by the Buddha, translated by Śrīmitra. Full article

Wangiri fraud is a pervasive telecommunications scam that exploits missed calls to lure victims into dialing premium-rate numbers, resulting in significant financial losses for operators and consumers. This paper presents a comprehensive machine learning framework for detecting Wangiri fraud in highly imbalanced and unlabeled Call Detail Record (CDR) datasets. We introduce a novel unsupervised labeling approach using domain-driven heuristics, coupled with advanced feature engineering to capture temporal, geographic, and behavioral patterns indicative of fraud. To address severe class imbalance, we evaluate multiple sampling strategies like the Synthetic Minority Over-sampling Technique (SMOTE) and undersampling, and also compare the performance of Logistic Regression, Decision Trees, Random Forest, XGBoost, and Multi-Layer Perceptron (MLP). Our results demonstrate that ensemble methods, particularly Random Forest and XGBoost, achieve near-perfect accuracy (e.g., Receiver Operating Characteristic Area Under the Curve (ROC-AUC) $>0.99$) on balanced data while maintaining interpretability. The proposed pipeline offers a scalable and practical solution for real-time fraud detection, providing telecom operators with an effective tool to mitigate Wangiri fraud risks. Full article

Background: Hospital In The Home (HITH), also called Hospital at Home or Virtual Hospital, delivers hospital-level care in patients’ homes to enhance outcomes and reduce hospital bed occupancy. Despite widespread implementation, strategic guidance for managing HITH initiatives remains limited. Methods: Following PRISMA 2020 guidelines, we conducted a systematic review (protocol not registered) searching ScienceDirect and Scopus (inception to December 2023) using the terms “hospital in the home,” “HITH,” “hospital at home,” “virtual care” AND “lesson,” “management,” “governance.” Peer-reviewed studies reporting lessons learned, best practices, or governance strategies for HITH programs with sufficient implementation detail were included; we excluded studies focusing solely on clinical effectiveness without organizational aspects, conference abstracts, and editorials. Two researchers independently screened records, extracted data, and conducted thematic analysis. Quality assessment used the Mixed Methods Appraisal Tool (MMAT). Sixteen studies (12 high-quality, 3 moderate, 1 low) were included. The studies were moderate overall, based on predominantly observational program evaluations and case studies. Results: Forty-two lessons were identified and classified into nine categories: combining care modalities, technology integration, impact on patient outcomes, training and specialized knowledge, care coordination, governance structures, financial sustainability, cross-sector collaboration, and patient selection. These categories fall under four themes: care delivery models; staffing and team dynamics; governance and financial sustainability; and patient selection and safety. Conclusions: This framework provides healthcare executives and program managers with evidence-based guidance for implementing and enhancing HITH programs, addressing a critical gap in governance and management literature. Full article

Background: Nasopharyngeal carcinoma (NPC) is an uncommon malignancy with a distinct geographical distribution. However, data from non-endemic areas are limited. This study aims to evaluate oncological outcomes and identify prognostic factors in a large cohort of non-metastatic NPC patients treated at a tertiary center in Israel. Methods: This single-institution, retrospective study included 181 patients diagnosed with non-metastatic NPC and treated with radiotherapy between 2005 and 2022. Data were collected from electronic medical records and included demographics, disease characteristics, treatment details, and outcomes. Recurrence-free survival (RFS) and overall survival (OS) were estimated using Kaplan–Meier analysis. Cox proportional hazards models were used to assess prognostic factors. Results: The median follow-up was 57 months. The cohort was predominantly male (82%), with a mean age of 51.7 years. Most patients had non-keratinizing histology, 75%presented with stage III–IV disease, and 86% received concurrent chemoradiotherapy. Induction chemotherapy was administered to 71%, though only 6.5% received the full three-cycle regimen. Nearly 90% were treated using modern radiotherapy techniques (VMAT), and 75% received concurrent chemotherapy. The 3-year RFS and OS were 82.6% and 91.2%, respectively; the 5-year RFS and OS were 77.7% and 84.7%. Age threshold analysis demonstrated that younger age predicted improved RFS (HR range, 3–5; p < 0.05). In the multivariate analysis, patients aged > 50 years had a significantly higher risk of recurrence (HR 6.02, 95% CI 1.30–27.85), while stage IV disease showed a borderline association with poorer RFS (HR 2.81, 95% CI 0.96–8.27), reaching statistical significance in the 30–50 years age group (HR = 7.06, 95% CI 1.14–43.76, p = 0.036). Smoking demonstrated a non-significant trend toward increased recurrence risk (HR 1.61, 95% CI 0.85–3.04). Similar patterns were seen for OS, with age >50 showing elevated but non-significant risk (HR 3.43, 95% CI 0.73–16.06), partly due to limited events. Bedouin ethnicity was associated with higher prevalence and a significantly younger age at diagnosis (39.4 ± 16.0 vs. 52.7 ± 16.9 years, p = 0.004), with a non-significantly better outcome. Conclusions: In this non-endemic cohort, favorable oncologic outcomes were observed. The age at diagnosis is a key prognostic factor. The higher incidence, younger age and better outcomes among the Bedouin ethnicity warrant further investigation calling for improved risk stratification and personalized treatment strategies. Full article

Advertisement calls play a crucial role in anuran species recognition and mate selection, yet acoustic characteristics of Zhangixalus lishuiensis remain undescribed. This study presents the first detailed acoustic analysis of advertisement calls in Zhangixalus lishuiensis from Lishui, Zhejiang Province, China. Based on recordings from 13 males collected in the field during the breeding season, we documented a hierarchical call structure consisting of three note types (Initial Note, Middle Note, and Short Note) organized into two note groups (Note Group 1 (NG1) and Note Group 2). Four structural variants of NG1 were identified, revealing intra-individual acoustic diversity within the population. Compared to the closely related Z. zhoukaiyae from the Dabie Mountains population, male Z. lishuiensis produced calls with significantly longer temporal parameters but lower dominant frequency, despite overall structural similarity, indicating acoustic divergence between these taxa. Comparative analysis across eleven Zhangixalus species revealed substantial variation in call durationand dominant frequency. These findings enrich the bioacoustic characterization of Zhangixalus and establish a foundation for acoustic-based species identification, monitoring, and taxonomic studies in this genus. Full article

Military readiness and performance are critical to national defense. Service Members must maintain their health and fitness to remain deployable. Dietary supplement use in the military is prevalent and remains a significant concern due to rampant misinformation, product adulteration, and documented adverse events. In March 2022, the Department of Defense issued Instruction (DoDI) 6130.06: Use of Dietary Supplements in the DoD, formally establishing Operation Supplement Safety (OPSS) [¹] as the program of record for everything related to dietary supplements. Leaders, as role models within their organizations, can serve as facilitators in promoting the safe and informed use of dietary supplements in the military through an innovative framework called Leader-Inspired Nutrition (LIN). LIN is a leadership-driven strategy aimed at enhancing Service Members’ health, encompassing seven pillars focused on nutritional fitness, including the informed and safe use of dietary supplements. This paper details how leaders can engage with Service Members and advocate for the safe use of dietary supplements by utilizing five strategic imperatives, educational initiatives, and resources provided by OPSS. Full article

Detailed paleomagnetic and rock magnetic investigations of the Paks loess (Hungary) were conducted to determine the stratigraphic position of the Matuyama–Brunhes Transition (MBT) and to attempt to reveal the sign of any possible influences of geomagnetic field change on the climate during the geomagnetic polarity reversal. Progressive thermal and alternating field demagnetizations of samples showed that the reverse polarity field begins to fluctuate in a stratigraphic position of the well-developed, so-called Paks Double 2 (PD2) paleosol (formed in Marine Isotope Stage 19, MIS19), and continues up to the middle-to-upper part of the overlying paleosol-to-loess transition layer (MIS19 to 18). Considering the relative paleointensity variation from Paks, this is consistent with various global records. Along with the weakening of the geomagnetic field, changes in environmental proxies were also recognized. Magnetic proxies indicate cooling during the MIS19 interglacial period. Theoretically, it may be connected to the weakening of the geomagnetic field. Still, there are alternatives to be considered, which may form the same features thought to be the result of the Umbrella effect. Full article

Climate change intensifies the challenges surrounding water cycling and vegetation dynamics in arid desert ecosystems, calling for detailed observations to decode adaptive plant strategies and support restoration efforts. This study analyzes interannual variations in water budgets and vegetation coverage in two distinct desert systems—K. foliatum (midstream) and R. songarica (downstream)—within the Heihe River Basin from 2016 to 2021. We uncover a pronounced ecohydrological contrast: the K. foliatum ecosystem displays substantial soil moisture variability alongside high precipitation and evapotranspiration rates, leading to a soil water deficit. In contrast, the R. songarica ecosystem maintains minimal moisture fluctuation under extreme aridity, yet records a slight water surplus. Notably, vegetation coverage in K. foliatum closely correlates with soil water storage, precipitation, and evapotranspiration, whereas R. songarica exhibits no significant hydrological coupling, implying a pulsed response to episodic rainfall. Groundwater recharge emerges as a key compensatory mechanism against rainfall shortages in midstream regions. These findings underscore the need for region-specific management—prioritizing groundwater conservation downstream and intelligent irrigation regulation midstream—offering a science-backed pathway for restoring and managing water resources in arid inland basins under climate change. Full article

This article examines the historical evolution, contemporary dynamics, and future trajectory of China’s legal and judicial framework for pangolin protection. By reviewing over seventy years of regulatory changes, case law, and policy implementation, it outlines three distinct phases: the early emphasis on pangolins as medicinal and export resources (1949–1989); the phase of conflicted protection and utilization under regulatory expansion (1989–2020); and the post-2020 shift toward judicial activism and ecological civil litigation. We then highlight the long-standing contradiction between legislative protection and continued medicinal use, particularly the centuries-old use of pangolins and their derivatives in traditional Chinese medicine, a practice still acknowledged within certain state policies and regulatory frameworks, showing how these inconsistencies enabled persistent illegal exploitation despite regulatory controls. Through systematic analysis of public court records and case databases, the policy historical records reveal a marked increase in environmental public interest litigation since 2020. These lawsuits, often attached to criminal prosecutions, signal a transition from merely punitive approaches to restorative ones—anchored in ecological valuation of species and their services. Case studies illustrate how courts now impose not only wildlife resource loss fees, but also punitive damages and compensation for ecological service function loss. The article will elaborate in detail on the distinctions and interrelations among these types of compensation. The landmark Case No.17 also demonstrates this paradigm shift, wherein courts recognized pangolins’ role in balancing forest ecosystems. However, significant challenges persist. Valuation methodologies lack uniform standards; while the ecological value of pangolins has been recognized, their inherent value as individuals has not been emphasized within the legal system; judicial discretion varies across jurisdictions; and public interest organizations remain underutilized in litigation. Moreover, while the crackdown on organized crime succeeded in curbing mass trafficking, smaller-scale violations tied to cultural consumption for medicine use persist. The article concludes that judicial innovations, such as ecological judicial restoration bases and integration into China’s draft Ecological Environment Code, offer promising pathways forward. To enhance efficacy, it calls for standardization in ecological valuation, strengthened civil society participation, and nuanced differentiation in penal strategies between minor and serious offenses. This study ultimately positions judicial reform as the cornerstone of China’s evolving pangolin conservation strategy. Full article

The growing complexity of urban mobility necessitates more adaptive, data-driven approaches to transport demand forecasting. This study incorporates anonymized Call Detail Record (CDR) data—originally collected for mobile network billing—into the conventional four-step travel demand model to more accurately estimate trip behavior. Employing a stay-based method, significant user locations are identified, and individual mobility patterns are reconstructed. These patterns are then aggregated at the zonal level and validated against a large-scale household survey conducted in Sri Lanka. The proposed framework enables the extraction of origin–destination matrices and supports route assignment using CDR data, demonstrating a strong correlation with traditional survey results. This research highlights the potential of repurposed CDR data as a scalable, cost-efficient alternative to conventional travel surveys for estimating travel demand. Full article