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4 Results Found

  • Article
  • Open Access
14 Citations
2,568 Views
16 Pages

Molecular Fingerprint of Human Pathological Synoviocytes in Response to Extractive Sulfated and Biofermentative Unsulfated Chondroitins

  • Valentina Vassallo,
  • Antonietta Stellavato,
  • Rosita Russo,
  • Donatella Cimini,
  • Mariangela Valletta,
  • Alberto Alfano,
  • Paolo Vincenzo Pedone,
  • Angela Chambery and
  • Chiara Schiraldi

14 December 2022

Pharma-grade extractive chondroitin sulfate (CS) is widely used for osteoarthritis (OA) treatment. Recently, unsulfated biofermentative chondroitin (BC) proved positive effects in OA in vitro model. This study, based on primary pathological human syn...

  • Article
  • Open Access
8 Citations
2,945 Views
16 Pages

9 October 2023

Currently, chondroitin sulfate (CS) and hyaluronic acid (HA) pharma-grade forms are used for osteoarthritis (OA) management, CS as an oral formulations component, and HA as intra-articular injective medical devices. Recently, unsulfated chondroitin,...

  • Article
  • Open Access
8 Citations
4,306 Views
21 Pages

Potential of Biofermentative Unsulfated Chondroitin and Hyaluronic Acid in Dermal Repair

  • Antonella D’Agostino,
  • Annalisa La Gatta,
  • Antonietta Stellavato,
  • Donatella Cimini,
  • Luisana Corsuto,
  • Marcella Cammarota,
  • Maria D’Agostino and
  • Chiara Schiraldi

1 February 2022

Chondroitin obtained through biotechnological processes (BC) shares similarities with both chondroitin sulfate (CS), due to the dimeric repetitive unit, and hyaluronic acid (HA), as it is unsulfated. In the framework of this experimental research, fo...

  • Correction
  • Open Access
1 Citations
1,185 Views
2 Pages