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Search Results (362)

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22 pages, 553 KiB  
Article
What Drives “Group Roaming”? A Study on the Pathway of “Digital Persuasion” in Media-Constructed Landscapes Behind Chinese Conformist Travel
by Chao Zhang, Di Jin and Jingwen Li
Behav. Sci. 2025, 15(8), 1056; https://doi.org/10.3390/bs15081056 - 4 Aug 2025
Viewed by 99
Abstract
In the era of digital intelligence, digital media landscapes increasingly influence cultural tourism consumption. Consumerism capitalizes on tourists’ superficial aesthetic commonalities, constructing a homogenized media imagination that leads to collective convergence in travel decisions, which obscures aspects of local culture, poses safety risks, [...] Read more.
In the era of digital intelligence, digital media landscapes increasingly influence cultural tourism consumption. Consumerism capitalizes on tourists’ superficial aesthetic commonalities, constructing a homogenized media imagination that leads to collective convergence in travel decisions, which obscures aspects of local culture, poses safety risks, and results in fleeting local tourism booms. In this study, semistructured interviews were conducted with 36 tourists, and NVivo12.0 was used for three-level node coding in a qualitative analysis to explore the digital media attributions of conformist travel behavior. The findings indicate that digital media landscapes exert a “digital persuasion” effect by reconstructing self-experience models, directing the individual gaze, and projecting idealized self-images. These mechanisms drive tourists to follow digital traffic trends and engage in imitative behaviors, ultimately shaping the phenomenon of “group roaming”, grounded in the psychological effect of herd behavior. Full article
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12 pages, 855 KiB  
Article
Application of Integrative Medicine in Plastic Surgery: A Real-World Data Study
by David Lysander Freytag, Anja Thronicke, Jacqueline Bastiaanse, Ioannis-Fivos Megas, David Breidung, Ibrahim Güler, Harald Matthes, Sophia Johnson, Friedemann Schad and Gerrit Grieb
Medicina 2025, 61(8), 1405; https://doi.org/10.3390/medicina61081405 - 1 Aug 2025
Viewed by 166
Abstract
Background and Objectives: There is a global rise of public interest in integrative medicine. The principles of integrative medicine combining conventional medicine with evidence-based complementary therapies have been implemented in many medical areas, including plastic surgery, to improve patient’s outcome. The aim [...] Read more.
Background and Objectives: There is a global rise of public interest in integrative medicine. The principles of integrative medicine combining conventional medicine with evidence-based complementary therapies have been implemented in many medical areas, including plastic surgery, to improve patient’s outcome. The aim of the present study was to systematically analyze the application and use of additional non-pharmacological interventions (NPIs) of patients of a German department of plastic surgery. Materials and Methods: The present real-world data study utilized data from the Network Oncology registry between 2016 and 2021. Patients included in this study were at the age of 18 or above, stayed at the department of plastic surgery and received at least one plastic surgical procedure. Adjusted multivariable logistic regression analyses were performed to detect associations between the acceptance of NPIs and predicting factors such as age, gender, year of admission, or length of hospital stay. Results: In total, 265 patients were enrolled in the study between January 2016 and December 2021 with a median age of 65 years (IQR: 52–80) and a male/female ratio of 0.77. Most of the patients received reconstructive surgery (90.19%), followed by hand surgery (5.68%) and aesthetic surgery (2.64%). In total, 42.5% of the enrolled patients accepted and applied NPIs. Physiotherapy, rhythmical embrocations, and compresses were the most often administered NPIs. Conclusions: This exploratory analysis provides a descriptive overview of the application and acceptance of NPIs in plastic surgery patients within a German integrative care setting. While NPIs appear to be well accepted by a subset of patients, further prospective studies are needed to evaluate their impact on clinical outcomes such as postoperative recovery, pain management, patient-reported quality of life, and overall satisfaction with care. Full article
(This article belongs to the Section Surgery)
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13 pages, 1189 KiB  
Article
The Role of Biodegradable Temporizing Matrix in Paediatric Reconstructive Surgery
by Aikaterini Bini, Michael Ndukwe, Christina Lipede, Ramesh Vidyadharan, Yvonne Wilson and Andrea Jester
J. Clin. Med. 2025, 14(15), 5427; https://doi.org/10.3390/jcm14155427 - 1 Aug 2025
Viewed by 278
Abstract
Introduction: Biodegradable Temporizing Matrix (BTM) is a new synthetic dermal substitute suitable for wound closure and tissue regeneration. The data in paediatric population remain limited. The study purpose is to review the indications for BTM application in paediatric patients, evaluate the short-term and [...] Read more.
Introduction: Biodegradable Temporizing Matrix (BTM) is a new synthetic dermal substitute suitable for wound closure and tissue regeneration. The data in paediatric population remain limited. The study purpose is to review the indications for BTM application in paediatric patients, evaluate the short-term and long-term results, including complications and functional outcomes, as well as to share some unique observations regarding the use of BTM in paediatric population. Patients and Methods: Patients undergoing reconstructive surgery and BTM application during the last three years were included. Data collected included patient demographics, primary diagnosis, previous surgical management, post-operative complications and final outcomes. BTM was used in 32 patients. The indications varied including epidermolysis bullosa (n = 6), burns (n = 4), trauma (n = 7), infection (n = 4), ischemia or necrosis (n = 11). Results: The results were satisfying with acceptable aesthetic and functional outcomes. Complications included haematoma underneath the BTM leading to BTM removal and re-application (n = 1), BTM infection (n = 1) and split-thickness skin graft failure on top of BTM requiring re-grafting (n = 2). Conclusions: BTM can be a good alternative to large skin grafts, locoregional flaps or even free flaps. The big advantages over other dermal substitutes or skin grafts are that BTM is less prone to infection and offers excellent scarring by preserving the normal skin architecture. Specifically in children, BTM might not require grafting, resulting in spontaneous healing with good scarring. In critically ill patients, BTM reduces the operation time and there is no donor site morbidity. BTM should be considered in the reconstructive ladder when discussing defect coverage options in children and young people. Full article
(This article belongs to the Special Issue Trends in Plastic and Reconstructive Surgery)
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18 pages, 285 KiB  
Review
The Historical Evolution of the Role of Vegetation in the Enhancement and Conservation of Archaeological Sites: A Landscape Architecture Perspective Focused Mainly on Cases from Italy and Greece
by Electra Kanellou and Maria Papafotiou
Plants 2025, 14(15), 2302; https://doi.org/10.3390/plants14152302 - 25 Jul 2025
Viewed by 213
Abstract
Vegetation plays a multifaceted role in the enhancement and conservation of archaeological sites, functioning not only as an aesthetic element but also as a core component of landscape architecture practice. This review traces the historical evolution of vegetation management, though the lens of [...] Read more.
Vegetation plays a multifaceted role in the enhancement and conservation of archaeological sites, functioning not only as an aesthetic element but also as a core component of landscape architecture practice. This review traces the historical evolution of vegetation management, though the lens of landscape architecture, highlighting its potential as a design and planning tool for historical interpretation and sustainable integration of heritage sites into broader contexts. From Romantic landscaping ideals to modern interdisciplinary conservation frameworks, the review draws on key milestones such as the Athens and Venice Charters, and examines case studies like Rome’s Passeggiata Archeologica, the Acropolis slopes, Ruffenhofen Park, and Campo Lameiro. These examples illustrate how landscape architectural approaches can use vegetation to reconstruct lost architectural forms, enhance visitor engagement, and provide ecosystem functions. The article also addresses challenges related to historical authenticity, species selection, and ecological performance, arguing for future strategies that integrate archaeological sites into dynamic, living heritage systems, through collaborative, ecologically informed design. Full article
(This article belongs to the Special Issue Floriculture and Landscape Architecture—2nd Edition)
11 pages, 1768 KiB  
Case Report
Direct-to-Implant Prepectoral Breast Reconstruction with a Novel Collagen Matrix Following Nipple-Sparing Mastectomy: A Case Report
by Josip Banović, Zrinka Pribudić, Mia Buljubašić Madir, Vedran Beara, Luka Perić, Marija Čandrlić and Željka Perić Kačarević
Reports 2025, 8(3), 120; https://doi.org/10.3390/reports8030120 - 24 Jul 2025
Viewed by 261
Abstract
Background and Clinical Significance: Breast reconstruction following mastectomy is a critical aspect of treatment for many patients, offering both physical and psychological benefits. Traditional methods include autologous tissue flaps and implants, with implant-based techniques being the most prevalent in the Western world. [...] Read more.
Background and Clinical Significance: Breast reconstruction following mastectomy is a critical aspect of treatment for many patients, offering both physical and psychological benefits. Traditional methods include autologous tissue flaps and implants, with implant-based techniques being the most prevalent in the Western world. However, complications such as capsular contracture remain a concern. Acellular dermal matrices (ADM) have emerged as a valuable alternative, improving outcomes by reducing capsular contracture rates and enhancing tissue integration. Case Presentation: This case report presents the first use of a novel ADM, biocade® (biotrics bioimplants AG, Berlin, Germany) in breast reconstruction following a mastectomy. A 55-year-old female patient underwent a left-sided nipple-sparing mastectomy, followed by prepectoral direct-to-implant reconstruction using an ADM-wrapped implant. The patient tolerated the procedure well, with no immediate complications observed. Postoperative monitoring focused on wound healing and assessing for signs of complications related to the implant. The use of the ADM resulted into satisfactory aesthetic and functional outcomes. Conclusions: The successful outcome of this case highlights the potential benefits of using collagen matrices in breast reconstruction, particularly in preserving mastectomy scenarios. The immediate results and improved aesthetics offered by prepectoral direct-to-implant reconstruction with ADM align well with patient expectations for a more natural appearance and faster recovery. However, this case report also highlights the need for ongoing research to fully explore the potential of these biomaterials and address associated challenges. Full article
(This article belongs to the Section Surgery)
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13 pages, 505 KiB  
Systematic Review
Microsurgical Reconstruction with Free Tissue Transfer in Skin Cancer Patients: A Systematic Review
by Tito Brambullo, Stefano L’Erario, Francesco Marena, Roberta Carpenito, Alfio Luca Costa, Vincenzo Vindigni and Franco Bassetto
Cancers 2025, 17(14), 2371; https://doi.org/10.3390/cancers17142371 - 17 Jul 2025
Viewed by 350
Abstract
Background/Objectives: The gold standard of treatment for both melanoma and non-melanoma skin cancers is wide surgical resection to obtain oncological radicality, which occasionally results in functional or aesthetic impairment, potentially affecting quality of life. Despite the increased complexity of the technique, extended duration [...] Read more.
Background/Objectives: The gold standard of treatment for both melanoma and non-melanoma skin cancers is wide surgical resection to obtain oncological radicality, which occasionally results in functional or aesthetic impairment, potentially affecting quality of life. Despite the increased complexity of the technique, extended duration of hospitalization, and prolonged surgical operative times, microsurgery can facilitate the reconstruction of locally invasive skin cancers following ablative surgery and may yield superior functional and aesthetic outcomes. Consequently, microsurgical reconstruction is more likely to be necessary if a large skin tumor requires excision. However, the impact of this extensive and complex procedure on patients with skin cancer has not yet been fully elucidated. The objective of this research was to critically analyze the utilization of free flap reconstruction subsequent to skin cancer therapy. Through a comprehensive examination of published data, this study aimed to assess the potential benefits and drawbacks associated with this reconstructive approach. Methods: A systematic review of studies that were published from January 2004 to May 2024 was conducted using the MEDLINE online database search. To present an evidence summary and provide a systematic approach and quality assessment, the GRADE® rating was applied to the results. Results: This review summarizes the oncological and clinical data, including previous interventions, adjuvant and neoadjuvant therapies, nodal status, distant metastasis, and follow-up time. Surgical outcome parameters such as healing time, flap survival, revision rate success, and minor and major complications were documented. Along with the findings, a quality assessment of the studies was also provided. Conclusions: This systematic review underscores the extensive use and efficacy of microsurgery for reconstruction after skin cancer excision; however, the literature remains limited by inconsistent reporting of oncological outcomes and the lack of a standardized approach to evaluate the impact of free flap reconstruction on both immediate and long-term cancer-specific results. Full article
(This article belongs to the Special Issue New Concepts and Recent Advances in the Management of Skin Cancer)
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17 pages, 15661 KiB  
Article
A Powerful Approach in Visualization: Creating Photorealistic Landscapes with AI
by Gusztáv Jakab, Enikő Magyari, Benedek Jakab and Gábor Timár
Land 2025, 14(7), 1430; https://doi.org/10.3390/land14071430 - 8 Jul 2025
Viewed by 2944
Abstract
Landscape visualization plays a crucial role in various scientific and artistic fields, including geography, environmental sciences, and digital arts. Recent advancements in computer graphics have enabled more sophisticated approaches to landscape representation. The integration of artificial intelligence (AI) image generation has further improved [...] Read more.
Landscape visualization plays a crucial role in various scientific and artistic fields, including geography, environmental sciences, and digital arts. Recent advancements in computer graphics have enabled more sophisticated approaches to landscape representation. The integration of artificial intelligence (AI) image generation has further improved accessibility for researchers, allowing efficient creation of landscape visualizations. This study presents a comprehensive workflow for the rapid and cost-effective generation of photorealistic still images. The methodology combines AI applications, computational techniques, and photographic methods to reconstruct the historical landscapes of the Great Hungarian Plain, one of Europe’s most significantly altered regions. The most accurate and visually compelling results are achieved by using historical maps and drone imagery as compositional and stylistic references, alongside a suite of AI tools tailored to specific tasks. These high-quality landscape visualizations offer significant potential for scientific research and public communication, providing both aesthetic and informative value. The article, which primarily presents a methodological description, does not contain numerical results. To test the method, we applied a procedure: we ran the algorithm on a current topographic map of a sample area and compared the resulting image with the view model provided by Google Earth. Full article
(This article belongs to the Special Issue Integration of Remote Sensing and GIS for Land Use Change Assessment)
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21 pages, 2757 KiB  
Article
Video-Assisted Mastectomy with Immediate Breast Reconstruction: First Clinical Experience and Outcomes in an Eastern European Medical Center
by Adrian Daniel Tulin, Daniela-Elena Ion, Adelaida Avino, Daniela-Elena Gheoca-Mutu, Abdalah Abu-Baker, Andrada-Elena Țigăran, Teodora Timofan, Ileana Ostafi, Cristian Radu Jecan and Laura Răducu
Cancers 2025, 17(13), 2267; https://doi.org/10.3390/cancers17132267 - 7 Jul 2025
Viewed by 441
Abstract
Background/Objectives: The aim of this case series is to evaluate the outcomes and safety of video-assisted mastectomy, illustrating the harmonious collaboration of oncologic and plastic surgery. This novel minimally invasive technique allows immediate prosthetic reconstruction and represents a cost-effective alternative to robotic breast [...] Read more.
Background/Objectives: The aim of this case series is to evaluate the outcomes and safety of video-assisted mastectomy, illustrating the harmonious collaboration of oncologic and plastic surgery. This novel minimally invasive technique allows immediate prosthetic reconstruction and represents a cost-effective alternative to robotic breast surgery. Methods: Video-assisted, single-port nipple-sparing mastectomies were performed in patients with small to medium-sized breasts, followed by immediate direct-to-implant reconstruction with either prepectoral or dual plane implant placement. The patients’ electronic medical records were analyzed, including demographic characteristics, operative times and histopathology reports. Results: A total of 18 patients underwent successful video-assisted mastectomy, without conversion to traditional open procedure. Fifteen of the operations were risk-reducing mastectomies. Twelve patients had complementary procedures performed concurrently on the previously operated contralateral breast (delayed reconstruction/expander-to-implant exchange). Moreover, three patients benefited from additional minimally invasive techniques during the same surgery (prophylactic laparoscopic hysterectomy). Immediate breast reconstruction with polyurethane or microtextured breast implants up to 450 cc was performed, with satisfactory aesthetic outcomes and no cancer recurrences at 6 to 12 months postoperative follow-up. Early complications included transient hypercapnia, areolar congestion and cellulitis. No skin necrosis or implant-related complications were reported. The most frequently encountered late issues were contour irregularities. Conclusions: Video-assisted mastectomy facilitates the safe removal of proven pathologic or healthy breast tissue with minimal damage to the breast’s skin envelope, facilitating single-stage breast reconstruction. Full article
(This article belongs to the Special Issue Recent Advances and Challenges in Breast Cancer Surgery: 2nd Edition)
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20 pages, 2879 KiB  
Review
Optimizing Outcomes in Oncoplastic Breast-Conserving Surgery
by Aileen Gozali and Merisa Piper
J. Clin. Med. 2025, 14(13), 4806; https://doi.org/10.3390/jcm14134806 - 7 Jul 2025
Viewed by 612
Abstract
Oncoplastic breast-conserving surgery (OBCS), or oncoplastic surgery, has revolutionized the surgical management of breast cancer by integrating oncologic principles with reconstructive techniques to optimize both cancer control and aesthetic outcomes following breast-conserving surgery (BCS). Since its inception in the 1980s, the field has [...] Read more.
Oncoplastic breast-conserving surgery (OBCS), or oncoplastic surgery, has revolutionized the surgical management of breast cancer by integrating oncologic principles with reconstructive techniques to optimize both cancer control and aesthetic outcomes following breast-conserving surgery (BCS). Since its inception in the 1980s, the field has evolved significantly, incorporating a range of volume displacement and volume replacement strategies to restore breast contour after partial mastectomy. This review explores the current practices and key surgical considerations of OBCS. It highlights the role of preoperative multidisciplinary planning, patient selection, anatomical and vascular knowledge, and intraoperative technique in optimizing results. Barriers to access—including disparities in training, insurance, and geographic availability—are addressed, alongside efforts by professional societies like the American Society of Breast Surgeons (ASBS) to standardize definitions and practices. The review also outlines strategies for minimizing complications and enhancing oncologic, reconstructive, and patient-reported outcomes. By offering a comprehensive framework for clinical decision-making, this paper aims to support broader adoption and refinement of OBCS as a standard component of breast cancer care. Full article
(This article belongs to the Special Issue Current State of the Art in Breast Reconstruction)
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12 pages, 1773 KiB  
Review
Advances in 3D-Printed Implants for Facial Plastic Surgery
by Joan Birbe Foraster
Surg. Tech. Dev. 2025, 14(3), 22; https://doi.org/10.3390/std14030022 - 1 Jul 2025
Viewed by 585
Abstract
Facial reconstruction presents complex challenges due to the intricate nature of craniofacial anatomy and the necessity for individualized treatment. Conventional reconstructive methods—such as autologous bone grafts and prefabricated alloplastic implants—pose limitations, including donor site morbidity, implant rejection, and suboptimal aesthetic results. The emergence [...] Read more.
Facial reconstruction presents complex challenges due to the intricate nature of craniofacial anatomy and the necessity for individualized treatment. Conventional reconstructive methods—such as autologous bone grafts and prefabricated alloplastic implants—pose limitations, including donor site morbidity, implant rejection, and suboptimal aesthetic results. The emergence of 3D printing technology has introduced patient-specific implants (PSIs) that enhance anatomical fit, functional restoration, and biocompatibility. This review outlines the evolution of 3D-printed implants, key materials, computer-assisted design (CAD), and their applications across trauma, oncology, congenital conditions, and aesthetics. It also addresses current challenges and explores future directions, such as bioprinting, smart implants, and drug-eluting coatings. Full article
(This article belongs to the Special Issue New Insights into Plastic Aesthetic and Regenerative Surgery)
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11 pages, 2507 KiB  
Article
Drawing the Surgical Blueprint: Evaluating ChatGPT Versus Gemini Across Diverse Plastic Aesthetic Procedures
by Gianluca Marcaccini, Ishith Seth, Omar Shadid, Roberto Cuomo and Warren M. Rozen
Surgeries 2025, 6(3), 51; https://doi.org/10.3390/surgeries6030051 - 27 Jun 2025
Viewed by 436
Abstract
Preoperative facial markings are critical to surgical precision and aesthetic outcomes in plastic surgery, yet remain operator-dependent and variably documented. Generative artificial intelligence (AI), particularly large multimodal models, offers potential for the automated illustration of surgical plans. This study compares the performances of [...] Read more.
Preoperative facial markings are critical to surgical precision and aesthetic outcomes in plastic surgery, yet remain operator-dependent and variably documented. Generative artificial intelligence (AI), particularly large multimodal models, offers potential for the automated illustration of surgical plans. This study compares the performances of ChatGPT-4o and Gemini Advanced in generating standardised preoperative markings for aesthetic facial procedures. Methods: Six text prompts describing common facial aesthetic surgeries were developed using established marking protocols. Each prompt was submitted once to ChatGPT-4o and Gemini Advanced, yielding twelve illustrations. Three board-certified plastic surgeons independently evaluated the images using a five-domain Likert scale assessing incision clarity, anatomical accuracy, template conformity, clinical usefulness, and overall graphic quality. A composite score out of 25 was calculated. Data were analysed using paired t-tests, and interrater reliability was assessed with intraclass correlation coefficients. Results: ChatGPT-4o significantly outperformed Gemini Advanced in composite scores (mean 18.0 ± 1.4 vs. 13.9 ± 1.6, p = 0.001, Cohen’s d = 1.69). Superior performance was noted across all domains, particularly in clarity (mean difference 0.83, p = 0.002) and graphic quality (mean difference 0.90, p = 0.001). Interrater reliability was good (ICC = 0.82). Discussion: ChatGPT-4o demonstrated higher fidelity in translating surgical prompts into anatomically appropriate, clinically useful illustrations. However, neither system achieved the precision required for clinical implementation without revision. These models may serve as adjuncts in education and preliminary planning. Future work should explore model fine-tuning, surgeon-guided generation, and performance in reconstructive procedures. Full article
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11 pages, 2332 KiB  
Article
Immediate Breast Reconstruction with Fat-Graft-Augmented ICAP Flaps
by Francesco Klinger, Mattia Federico Cavallero, Andrea Vittorio Emanuele Lisa, Fernando Rosatti, Barbara Catania, Marco Klinger, Riccardo Di Giuli, Simone Furlan, Roberta Comunian, Stefano Vaccari and Valeriano Vinci
Life 2025, 15(7), 1017; https://doi.org/10.3390/life15071017 - 26 Jun 2025
Viewed by 555
Abstract
Background: Intercostal artery perforator (ICAP) flaps are a reliable option for volume replacement in breast-conserving surgery (BCS), particularly for lower pole defects. However, limited flap volume may reduce their applicability in selected patients. Autologous fat grafting has been proposed to enhance both volume [...] Read more.
Background: Intercostal artery perforator (ICAP) flaps are a reliable option for volume replacement in breast-conserving surgery (BCS), particularly for lower pole defects. However, limited flap volume may reduce their applicability in selected patients. Autologous fat grafting has been proposed to enhance both volume and aesthetic outcomes. Methods: This retrospective study evaluated 10 patients undergoing BCS with immediate reconstruction using fat-graft-augmented ICAP flaps. Nine anterior ICAP (AICAP) flaps and one lateral ICAP (LICAP) flap were employed. The outcomes included flap viability, complications, and aesthetic results over a 6-month follow-up. Results: Partial flap resorption occurred in 2 patients (20%), both of whom were active smokers. No cases of skin necrosis were observed. Fat grafting volumes ranged from 20 to 60 cc. Aesthetic outcomes were satisfactory, with good restoration of the breast contour and stable integration of the flap and grafted fat. Conclusions: The combined use of ICAP flaps and autologous fat grafting is a feasible and effective technique for immediate reconstruction after BCS. It allows volume enhancement, maintains natural contour, and shows low complication rates in properly selected patients. Smoking remains a significant risk factor. Full article
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12 pages, 235 KiB  
Review
The Role of Exclusive Autologous Lipotransfer in Non-Irradiated Breasts After Mastectomy
by Aikaterini-Gavriela Giannakaki, Eftychia Papachatzopoulou, Ioannis Papapanagiotou, Sophia Koura, Dimitris Baroutis, Spyridon Marinopoulos, George Daskalakis and Constantine Dimitrakakis
J. Clin. Med. 2025, 14(13), 4468; https://doi.org/10.3390/jcm14134468 - 24 Jun 2025
Viewed by 524
Abstract
Background/Objectives: Autologous fat grafting (AFT) has become a widely used technique in breast reconstruction, offering natural aesthetics, tissue integration, and patient satisfaction. However, its clinical outcomes require comparison with implant-based reconstruction (IBR), the most common method in clinical practice. While AFT provides a [...] Read more.
Background/Objectives: Autologous fat grafting (AFT) has become a widely used technique in breast reconstruction, offering natural aesthetics, tissue integration, and patient satisfaction. However, its clinical outcomes require comparison with implant-based reconstruction (IBR), the most common method in clinical practice. While AFT provides a more natural appearance and avoids foreign body-related complications, issues such as fat resorption, procedural variability, and oncological concerns necessitate further investigation. Additionally, artificial intelligence (AI) has been increasingly integrated into breast imaging and reconstructive planning, improving diagnostic accuracy, procedural optimization, and complication prevention. This study aims to compare AFT and IBR while exploring AI’s role in enhancing breast reconstruction outcomes. Methods: A comprehensive review of clinical studies was conducted to evaluate the advantages, limitations, and oncological implications of AFT versus IBR. AI-driven applications in breast imaging and reconstructive planning were examined for their potential in predicting fat graft retention and optimizing implant selection. Data from systematic reviews and meta-analyses were incorporated to refine reconstruction strategies. Results: AFT offers superior aesthetic outcomes with better tissue integration but presents variability in fat resorption. IBR remains the preferred approach due to its predictability but carries risks of implant-related complications. AI technologies contribute to improved reconstruction planning, enhancing surgical precision and long-term patient outcomes. Conclusions: Optimized patient selection and long-term follow-up are essential for improving breast reconstruction techniques. AI-driven approaches provide valuable tools for enhancing procedural predictability and personalized treatment strategies. Future research should focus on refining AI algorithms and establishing standardized protocols for reconstructive decision-making. Full article
(This article belongs to the Special Issue Breast Reconstruction: The Current Environment and Future Directions)
17 pages, 529 KiB  
Review
Techniques for Success in Nipple-Sparing Mastectomy and Immediate Reconstruction
by Jenn J. Park, Carter J. Boyd, Kshipra Hemal, Thomas J. Sorenson, Chris Amro, Nicholas A. Vernice, Alexis C. Lakatta, Oriana Cohen, Mihye Choi and Nolan S. Karp
J. Clin. Med. 2025, 14(12), 4363; https://doi.org/10.3390/jcm14124363 - 19 Jun 2025
Viewed by 646
Abstract
Background: Nipple-sparing mastectomy (NSM), given demonstrated oncologic safety, is widely used for both therapeutic and prophylactic mastectomy. The popularity of NSM has spurred advancements by breast and plastic surgeons, liberalizing the indications for NSM and improving patient and aesthetic reconstructive outcomes. This review [...] Read more.
Background: Nipple-sparing mastectomy (NSM), given demonstrated oncologic safety, is widely used for both therapeutic and prophylactic mastectomy. The popularity of NSM has spurred advancements by breast and plastic surgeons, liberalizing the indications for NSM and improving patient and aesthetic reconstructive outcomes. This review explores these developments and establishes up-to-date surgical tenets for successful NSM and reconstruction. Methods: A comprehensive literature review was conducted using the PubMed, Google Scholar, and Cochrane Library databases, focusing on peer-reviewed studies published up to 2024. Articles were selected based on relevance, quantity, and documentation of clinical outcomes and patient satisfaction. Results: NSM is utilized frequently for both invasive breast cancers and prophylactic mastectomy, with expanded criteria for candidacy by breast surgeons. Staged procedures such as adjunct reduction, mastopexy, or nipple delay allow patients with larger or ptotic breasts to undergo NSM with comparable outcomes. Long-term outcome studies have identified important risk factors for complications, including smoking history, higher mastectomy weight, certain medical comorbidities, and suboptimal mastectomy flaps. Evolutions in reconstructive decision making in direct-to-implant and staged tissue expander placement have improved aesthetic results while accounting for poor mastectomy flap quality or adjuvant therapy. Long-term outcomes show NSM remains safe and has comparable rates of local recurrence. Patient-reported outcomes demonstrate satisfaction with NSM, especially in sexual and psychological wellbeing metrics. Conclusions: NSM has been demonstrated to be safe in long-term oncologic outcomes. Its widespread popularity over the past ten years has helped identify methods to improve upon surgical and aesthetic outcomes, including decision-making in reconstruction; considerations for challenging patient-related characteristics such as macromastia, ptosis, and NAC asymmetry; and novel advances in areas such as neurotization. Full article
(This article belongs to the Special Issue Current State of the Art in Breast Reconstruction)
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35 pages, 392 KiB  
Guidelines
Postmastectomy Breast Reconstruction in Patients with Non-Metastatic Breast Cancer: An Ontario Health (Cancer Care Ontario) Clinical Practice Guideline
by Toni Zhong, Glenn G. Fletcher, Muriel Brackstone, Simon G. Frank, Renee Hanrahan, Vivian Miragias, Christiaan Stevens, Danny Vesprini, Alyssa Vito and Frances C. Wright
Curr. Oncol. 2025, 32(6), 357; https://doi.org/10.3390/curroncol32060357 - 17 Jun 2025
Viewed by 612
Abstract
Several postmastectomy breast reconstruction techniques and procedures have been implemented, although with limited evaluation of benefits and adverse effects. We conducted a systematic review on the plane and timing of reconstruction, and on the use of nipple-sparing mastectomy, acellular dermal matrix, and autologous [...] Read more.
Several postmastectomy breast reconstruction techniques and procedures have been implemented, although with limited evaluation of benefits and adverse effects. We conducted a systematic review on the plane and timing of reconstruction, and on the use of nipple-sparing mastectomy, acellular dermal matrix, and autologous fat grafting as the evidence base for an updated clinical practice guideline on breast reconstruction for Ontario Health (Cancer Care Ontario). Both immediate and delayed reconstruction may be considered, with preferred timing depending on factors such as patient preferences, type of mastectomy, skin perfusion, comorbidities, pre-mastectomy breast size, and desired reconstructive breast size. Immediate reconstruction may provide greater psychological or quality of life benefits. In patients who are candidates for skin-sparing mastectomy and without clinical, radiological, and pathological indications of nipple-areolar complex involvement, nipple-sparing mastectomy is recommended provided it is technically feasible and acceptable aesthetic results can be achieved. Surgical factors including incision location are important to reduce necrosis by preserving blood supply and to minimize nerve damage. There is a role for both prepectoral and subpectoral implants; risks and benefits will vary, and decisions should be made during consultation between the patient and surgeons. In patients who are suitable candidates for implant reconstruction and have adequate mastectomy flap thickness and vascularity, prepectoral implants should be considered. Acellular dermal matrix (ADM) has led to an increased use of prepectoral reconstruction. ADM should not be used in case of poor mastectomy flap perfusion/ischemia that would otherwise be considered unsuitable for prepectoral reconstruction. Care should be taken in the selection and handling of acellular dermal matrix (ADM) to minimize risks of infection and seroma. Limited data from small studies suggest that prepectoral reconstruction without ADM may be feasible in some patients. Autologous fat grafting is recommended as a treatment for contour irregularities, rippling following implant-based reconstruction, and to improve tissue quality of the mastectomy flap after radiotherapy. Full article
(This article belongs to the Section Breast Cancer)
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