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6 Results Found

  • Article
  • Open Access
5 Citations
2,346 Views
14 Pages

The Effect of a Magnetic Field on the Transport of Functionalized Magnetite Nanoparticles into Yeast Cells

  • Bernadeta Dobosz,
  • Eliza Gunia,
  • Klaudia Kotarska,
  • Grzegorz Schroeder and
  • Joanna Kurczewska

6 February 2024

Magnetic nanoparticles are of great interest to scientists as potential drug carriers. Therefore, it is essential to analyze the processes these nanoparticles undergo at the cellular level. The present paper demonstrates the effect of a constant and...

  • Article
  • Open Access
11 Citations
3,422 Views
16 Pages

ESR Method in Monitoring of Nanoparticle Endocytosis in Cancer Cells

  • Ryszard Krzyminiewski,
  • Bernadeta Dobosz,
  • Bart Krist,
  • Grzegorz Schroeder,
  • Joanna Kurczewska and
  • Hans A.R. Bluyssen

Magnetic nanoparticles are extensively studied for their use in diagnostics and medical therapy. The behavior of nanoparticles after adding them to cell culture is an essential factor (i.e., whether they attach to a cell membrane or penetrate the mem...

  • Article
  • Open Access
7 Citations
6,811 Views
14 Pages

Insights into a Protein-Nanoparticle System by Paramagnetic Perturbation NMR Spectroscopy

  • Yamanappa Hunashal,
  • Cristina Cantarutti,
  • Sofia Giorgetti,
  • Loredana Marchese,
  • Federico Fogolari and
  • Gennaro Esposito

7 November 2020

Background: The interaction between proteins and nanoparticles is a very relevant subject because of the potential applications in medicine and material science in general. Further interest derives from the amyloidogenic character of the considered p...

  • Article
  • Open Access
5 Citations
3,587 Views
19 Pages

Spin Probes as Scavengers of Free Radicals in Cells

  • Bernadeta Dobosz,
  • Ryszard Krzyminiewski,
  • Małgorzata Kucińska,
  • Marek Murias,
  • Grzegorz Schroeder and
  • Joanna Kurczewska

10 August 2022

Spin probes can be used to monitor biological membranes, including the penetration of different molecules into cells. The aim of the present studies was an investigation of the endocytosis process of two spin labels—2,2,6,6-Tetramethylpiperidin...

  • Article
  • Open Access
10 Citations
2,911 Views
10 Pages

Synthesis of Spin-Labeled Ibuprofen and Its Interaction with Lipid Membranes

  • Denis S. Baranov,
  • Anna S. Smorygina and
  • Sergei A. Dzuba

27 June 2022

Ibuprofen is a non-steroidal anti-inflammatory drug possessing analgesic and antipyretic activity. Electron paramagnetic resonance (EPR) spectroscopy could be applied to study its interaction with biological membranes and proteins if its spin-labeled...

  • Article
  • Open Access
7 Citations
2,549 Views
21 Pages

Direct Application of 3-Maleimido-PROXYL for Proving Hypoalbuminemia in Cases of SARS-CoV-2 Infection: The Potential Diagnostic Method of Determining Albumin Instability and Oxidized Protein Level in Severe COVID-19

  • Ekaterina Georgieva,
  • Vasil Atanasov,
  • Rositsa Kostandieva,
  • Vanya Tsoneva,
  • Mitko Mitev,
  • Georgi Arabadzhiev,
  • Yovcho Yovchev,
  • Yanka Karamalakova and
  • Galina Nikolova

Oxidative stress and the albumin oxidized form can lead to hypoalbuminemia, which is a predisposing factor for reduced treatment effectiveness and an increased mortality rate in severe COVID-19 patients. The aim of the study is to evaluate the applic...