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Article

3,852 Views

12 Pages

Detection of Neutralizing Antibodies in COVID-19 Patients from Steve Biko Academic Hospital Complex: A Pilot Study

Mankgopo Kgatle,
Joseph Musonda Chalwe,
Donald van der Westhuizen,
Shuting Xu,
Botle Precious Damane,
Precious Mathebela,
Veronica Ueckermann,
Simnikiwe Mayaphi,
Hosana Gomes Rodrigues and
Mike Sathekge
+ 6 authors

COVID2023, 3(7), 999-1010;https://doi.org/10.3390/covid3070072

3 July 2023

A correlation between neutralization activity after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination and protection against coronavirus disease 2019 (COVID-19) has been demonstrated by several studies. Here, we detect SARS-CoV...

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Article

6 Citations

2,977 Views

14 Pages

The Case for Pre-Emptive Pharmacogenetic Screening in South Africa

Tracey Hurrell,
Jerolen Naidoo,
Collen Masimirembwa and
Janine Scholefield

J. Pers. Med.2024, 14(1), 114;https://doi.org/10.3390/jpm14010114

19 January 2024

Lack of equitable representation of global genetic diversity has hampered the implementation of genomic medicine in under-represented populations, including those on the African continent. Data from the multi-national Pre-emptive Pharmacogenomic Test...

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Article

3 Citations

3,755 Views

13 Pages

The SARS-COV-2 Seroprevalence among Oncology Patients

Mankgopo Kgatle,
Rajesh Das,
Ismaheel Lawal,
Tebatso Boshomane,
Kgomotso Mokoala,
Cattleya Gaspar,
Lydia Mbokazi,
Nonhlanhla Nkambule,
Veronique Gow and
Mike Sathekge
+ 14 authors

J. Clin. Med.2023, 12(2), 529;https://doi.org/10.3390/jcm12020529

9 January 2023

Patients with cancer are presumed to be vulnerable to an increased risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and severe clinical outcomes due to the immunocompromised state mediated by their underlying malignancie...

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Article

1 Citations

1,736 Views

20 Pages

T-Cell Phenotypes and Systemic Cytokine Profiles of People Living with HIV Admitted to Hospital with COVID-19

Mieke A. van der Mescht,
Helen C. Steel,
Zelda de Beer,
Andries Masenge,
Fareed Abdullah,
Veronica Ueckermann,
Ronald Anderson and
Theresa M. Rossouw

Microorganisms2024, 12(11), 2149;https://doi.org/10.3390/microorganisms12112149

25 October 2024

Whether SARS-CoV-2 infection leads to a higher mortality and morbidity in people living with HIV (PLWH) in Africa remains inconclusive. In this study, we explored the differences in the T-cell phenotypes between people with and without HIV on the day...

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