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4 Results Found

  • Article
  • Open Access
15 Citations
4,313 Views
20 Pages

Nutrient limitation and nonfavorable growth conditions have been suggested to be major triggers for the expression of small, cysteine-rich antimicrobial proteins (AMPs) of fungal origin, e.g., the Penicillium chrysogenum antifungal protein (PAF), the...

  • Article
  • Open Access
32 Citations
5,490 Views
13 Pages

Potential of Antifungal Proteins (AFPs) to Control Penicillium Postharvest Fruit Decay

  • Mónica Gandía,
  • Anant Kakar,
  • Moisés Giner-Llorca,
  • Jeanett Holzknecht,
  • Pedro Martínez-Culebras,
  • László Galgóczy,
  • Florentine Marx,
  • Jose F. Marcos and
  • Paloma Manzanares

4 June 2021

Penicillium phytopathogenic species provoke severe postharvest disease and economic losses. Penicillium expansum is the main pome fruit phytopathogen while Penicillium digitatum and Penicillium italicum cause citrus green and blue mold, respectively....

  • Article
  • Open Access
27 Citations
5,588 Views
21 Pages

The Penicillium chrysogenum Q176 Antimicrobial Protein PAFC Effectively Inhibits the Growth of the Opportunistic Human Pathogen Candida albicans

  • Jeanett Holzknecht,
  • Alexander Kühbacher,
  • Csaba Papp,
  • Attila Farkas,
  • Györgyi Váradi,
  • Jose F. Marcos,
  • Paloma Manzanares,
  • Gábor K. Tóth,
  • László Galgóczy and
  • Florentine Marx

19 August 2020

Small, cysteine-rich and cationic antimicrobial proteins (AMPs) from filamentous ascomycetes promise treatment alternatives to licensed antifungal drugs. In this study, we characterized the Penicillium chrysogenum Q176 antifungal protein C (PAFC), wh...

  • Review
  • Open Access
12 Citations
5,438 Views
10 Pages

The discovery and understanding of the mode of action of new antimicrobial agents is extremely urgent, since fungal infections cause 1.5 million deaths annually. Antifungal peptides and proteins represent a significant group of compounds that are abl...