Search Results (85)

Electrical connectors play a vital role in ensuring reliable signal transmission in high-frequency microsystems. This study explores the impact of microscale scratch-induced surface roughness on the alternating current (AC) contact impedance of RF coaxial connectors. Unlike traditional approaches that assume idealized surface conditions, controlled micro-defects were introduced at the central contact interface to establish a quantitative relationship between surface morphology and signal degradation. An equivalent circuit model was constructed to account for local impedance variations and the cumulative effects of cascaded connector interfaces. The model was validated using S-parameter measurements obtained from vector network analyzer (VNA) testing, showing strong agreement with simulation results. Experimental results reveal that the low-roughness (0.4 μm) contact surfaces lead to degraded signal integrity due to insufficient micro-contact formation. In contrast, scratch-induced moderate roughness (0.8–4.8 μm) improves transmission performance, although signal quality declines as roughness increases within this range. These effects are further amplified in multi-connector configurations due to accumulated impedance mismatches. This work provides new insight into the coupling between microscale surface features and frequency-domain transmission characteristics, offering practical guidance for surface engineering, contact design, and the development of miniaturized, high-reliability radio frequency interconnects for next-generation communication systems. Full article

Background/Objectives: Intracranial macroelectrode implantation is a pivotal clinical tool in the evaluation of drug-resistant epilepsy, allowing further insights into the localization of the epileptogenic zone and the delineation of eloquent cortical regions through cortical stimulation. Additionally, it provides an avenue to study brain functions by analyzing cerebral responses during neuropsychological paradigms. By combining macroelectrodes with microelectrodes, which allow recording the activity of individual neurons or smaller neural clusters, recordings could provide deeper insights into neuronal microcircuits and the brain’s transitions in epilepsy and contribute to a better understanding of neuropsychological functions. In this study, one or two hybrid macro-micro electrodes were implanted in the anterior-inferior insular region in patients with refractory epilepsy. We report our experience and share some preliminary results; we also provide some recommendations regarding the implantation procedure for hybrid electrodes in the insular cortex. Methods: Stereoelectroencephalography was performed in 13 patients, with one or two hybrid macro-microelectrodes positioned in the insular region in each patient. Research neuropsychological paradigms could not be implemented in two patients for clinical reasons. In total, 23 hybrid macro-microelectrodes with eight microcontacts each were implanted, of which 20 were recorded. Spiking activity was detected and assessed using WaveClus3. Results: No spiking neural activity was detected in the microcontacts of the first seven patients. After iterative refinement during this process, successful recordings were obtained from 13 microcontacts in the anterior-inferior insula in the last four patients (13/64, 20.3%). Hybrid electrode implantation was uneventful with no complications. Obstacles included the absence of spiking activity signals, unsuccessful microwire dispersion, and the interference of environmental electrical noise in recordings. Conclusions: Human microelectrode recording presents a complex array of challenges; however, it holds the potential to facilitate a more comprehensive understanding of individual neuronal attributes and their specific stimulus responses. Full article

For organ-on-a-chip (OoC) engineering, the use of biocompatible coatings and materials is not only recommended but essential. Extracellular matrix (ECM) components are commonly used as coatings due to their effects on cell orientation, protein expression, differentiation, and adhesion. Among the most frequently used coatings are collagen, fibronectin, and Matrigel, according to the specific cell type and intended OoC application. Additionally, materials such as polydimethylsiloxane (PDMS), thermoplastics, chitosan, and alginate serve as scaffolding components due to their biomechanical properties and biocompatibility. Here, we discuss some of the most employed coating techniques, including SAMs, dip coating, spin coating, microcontact printing, and 3D bioprinting, each offering advantages and drawbacks. Current challenges comprise enhancing biocompatibility, exploring novel materials, and improving scalability and reproducibility. Full article

This study addresses the critical challenge of precise control over active abrasive particles in magnetorheological polishing (MRP) through innovative core–shell particle engineering. A sol–gel synthesized CIP@SiO₂ magnetic composite abrasive with controlled SiO₂ encapsulation (20 nm shell thickness) was developed using tetraethyl orthosilicate (TEOS) as the silicon precursor, demonstrating significant advantages in optical-grade fused silica finishing. Systematic polishing experiments reveal that the core–shell architecture achieves a remarkable 20.16% improvement in surface quality (Ra = 1.03 nm) compared to conventional CIP/SiO₂ mixed abrasives, with notably reduced surface defects despite a modest 8–12% decrease in material removal rate. Through synergistic analysis combining elastic microcontact mechanics modeling and molecular dynamics simulations, we establish that the SiO₂ shell mediates stress distribution at tool–workpiece interfaces, effectively suppressing deep subsurface damage while maintaining nano-scale material removal efficiency. The time-dependent performance analysis further demonstrates that extended polishing durations with CIP@SiO₂ composites progressively eliminate mid-spatial frequency errors without introducing new surface artifacts. These findings provide fundamental insights into designed abrasive architectures for precision finishing applications requiring sub-nanometer surface integrity control. Full article

At the microscale, the three-dimensional morphological features of contact surfaces have a significant impact on the performance of electrical contacts. This paper aims to reconstruct the microscopic contact state of contact groups and to deeply study the effect of contact morphological features on electrical contact performance. To fully obtain multimodal data such as the three-dimensional micro-morphological features and chemical composition distribution of contact surfaces, this paper proposes a contact surface feature-matching method based on entropy rate superpixel seed point adaptive morphological reconstruction. This method can adaptively retain meaningful seed points while filtering out invalid seed points, effectively solving the problem of over-segmentation in traditional superpixel segmentation method. Experimental results show that the proposed method achieves a segmentation accuracy of 92% and reduces over-segmentation by 30% compared to traditional methods. Subsequently, on the basis of the moving and static contact group difference plane model and the W-M model, this paper constructs a three-dimensional surface fractal contact model with an irregular base. This model has the ability to layer simulate multi-parameter elastic and plastic and to extract fractal parameter point cloud height, which can more accurately reflect the actual contact state of the contact group. The model demonstrates a 15% improvement in contact area prediction accuracy and a 20% reduction in contact resistance estimation error compared to existing models. Finally, this paper compares and verifies the theoretical feasibility of the model, providing a new theoretical contact model for the study of the impact of three-dimensional micro-morphology on the electrical contact reliability. Full article

This study presents the challenges arising during the numerical design and simulation of surface-microtextured piston rings. The evaluation of performance is based on the values of asperity and hydrodynamic friction, as well as the lubricant film thickness. The simulation tool AVL Excite Piston & Rings is used to perform the calculations. The aim of this study is to understand how selected surface pre-processing (pre-treatment) steps affect the calculations. Two methods are presented to achieve a realistic surface topography representative of a state after running-in. Pre-treatment is performed through metrological filtering and thresholding of the topography, and Gaussian smoothing of the virtually applied micro-texture array is carried out. The results show the anticipated behavior of decreasing asperity and hydrodynamic friction losses with the concurrent application of both techniques. Full article

Microcontact printing (µCP) has become an emerging method for creating exact patterns on a range of substrates. This short review paper seeks to give a brief summary of the developments, fabrication techniques, applications, and difficulties in the microcontact printing of polymeric devices. In this systematic review, 20 papers from various fields were chosen for study. This review begins by introducing the basics of microcontact printing and discussing its capacity to transfer predetermined patterns with submicron resolution from an elastomeric stamp to substrates. Then, various microcontact printing production techniques for polymeric devices are reviewed. Furthermore, this review explores the broad range of applications enabled by microcontact printing, including electronics, biotechnology, nanotechnology, and surface engineering. Additionally, the potential difficulties and challenges associated with using microcontact printing processes are discussed. This literature review is to give researchers and practitioners a thorough understanding of microcontact printing by integrating the results from a few chosen studies. It promotes additional study and innovation in this promising sector by highlighting the most recent advancements, manufacturing techniques, and difficulties related to the manufacture of polymeric devices. Full article

Alzheimer’s disease (AD) is a neurodegenerative disease characterized by memory loss and progressive deterioration of cognitive functions. Being able to identify reliable biomarkers in easily available body fluids such as blood plasma is vital for the disease. To achieve this, we used a technique that applied human plasma to organotypic brain slice culture via microcontact printing. After a 2-week culture period, we performed immunolabeling for neurofilament and myelin oligodendrocyte glycoprotein (MOG) to visualize newly formed nerve fibers and oligodendrocytes. There was no significant change in the number of new nerve fibers in the AD plasma group compared to the healthy control group, while the length of the produced fibers significantly decreased. A significant increase in the number of MOG+ dots around these new fibers was detected in the patient group. According to our hypothesis, there are factors in the plasma of AD patients that affect the growth of new nerve fibers, which also affect the oligodendrocytes. Based on these findings, we selected the most promising plasma samples and conducted mass spectrometry using a differential approach and we identified three putative biomarkers: aldehyde-dehydrogenase 1A1, alpha-synuclein and protein S100-A4. Our method represents a novel and innovative approach for translating research findings from mouse models to human applications. Full article

Engineering practice has demonstrated that seal failure can result in severe leakage and wear, reducing the efficiency of hydraulic systems and even leading to major safety risks. Currently, analyses of the thermal aspect of seal interfaces are relatively limited, with most studies focusing on mechanical analysis. However, in actual applications, temperature has a significant impact on sealing performance. In this paper, nonlinear elastomechanics, viscous fluid mechanics, micro-contact mechanics, micro-deformation theory, and thermodynamics are coupled to establish a mixed lubrication model considering the thermal effect. The reliability of the mixed lubrication model is verified through experiments, and the temperature distribution of the oil film in the sealing area and the temperature distribution of the seal ring are simulated. Finally, the effects of the reciprocating speed, root mean square roughness, fluid medium pressure, and seal pre-compression on seal friction force and leakage are investigated. The results show that the heat generated in the sealing area accumulates at the bottom of the V-ring. Under the same conditions, compared with the instroke, the temperature-rise area of the outstroke is biased to the left and the increase in temperature is greater. In addition, the piston rod speed and the preliminary compression of the seal ring have a greater impact on the overall seal friction force and leakage. Under a lower seal pre-compression, the RMS roughness has a great influence on the leakage and friction in the outstroke, while the impact of the internal stroke is limited. Full article

This review explores significant advancements in polymer science and fabrication processes that have enhanced the performance and broadened the application scope of microfluidic devices. Microfluidics, essential in biotechnology, medicine, and chemical engineering, relies on precise fluid manipulation in micrometer-sized channels. Recent innovations in polymer materials, such as flexible, biocompatible, and structurally robust polymers, have been pivotal in developing advanced microfluidic systems. Techniques like replica molding, microcontact printing, solvent-assisted molding, injection molding, and 3D printing are examined, highlighting their advantages and recent developments. Additionally, the review discusses the diverse applications of polymer-based microfluidic devices in biomedical diagnostics, drug delivery, organ-on-chip models, environmental monitoring, and industrial processes. This paper also addresses future challenges, including enhancing chemical resistance, achieving multifunctionality, ensuring biocompatibility, and scaling up production. By overcoming these challenges, the potential for widespread adoption and impactful use of polymer-based microfluidic technologies can be realized. Full article

Alzheimer’s disease is a severe neurodegenerative disorder, and the discovery of biomarkers is crucial for early diagnosis. While the analysis of biomarkers in cerebrospinal fluid is well accepted, there are currently no blood biomarkers available. Our research focuses on identifying novel plasma biomarkers for Alzheimer’s disease. To achieve this, we employed a technique that involves coupling human plasma to mouse organotypic brain slices via microcontact prints. After culturing for two weeks, we assessed Iba1-immunopositive microglia on these microcontact prints. We hypothesized that plasma from Alzheimer’s patients contains factors that affect microglial migration. Our data indicated that plasma from Alzheimer’s patients significantly inhibited the migration of round Iba1-immunoreactive microglia (13 ± 3, n = 24, p = 0.01) compared to healthy controls (50 ± 16, n = 23). Based on these findings, we selected the most promising plasma samples and conducted mass spectrometry using a differential approach, and we identified four potential biomarkers: mannose-binding protein C, macrophage receptor MARCO, complement factor H-related protein-3, and C-reactive protein. Our method represents a novel and innovative approach to translate research findings from mouse models to human applications. Full article

This paper presents an initial study of the acceptability of differential object marking (DOM) by Galician–Spanish bilinguals in Galicia. The research explores judgments provided by these bilinguals (n = 69) on DOM in both Galician and Spanish and it also explores data from a monolingual Spanish control group (n = 12). The surveys target contexts covering key syntactic and semantic–pragmatic contexts for DOM in Galician and Spanish, based on the existing literature. The Galician data reveal a tendency towards reduced acceptability of DOM compared to Spanish, but without a generalized rejection of DOM in any of the contexts. The Spanish data show variability in both groups. The study contributes insights from an under-studied language pair and aims to open avenues for further work. More generally, it enhances our understanding of DOM in bilingual grammars, particularly in microcontact situations. Full article

Perfluorododecyl iodide (I-PFC12) is of interest for area-selective deposition (ASD) applications as it exhibits intriguing properties such as ultralow surface energy, the ability to modify silicon’s band gap, low surface friction, and suitability for micro-contact patterning. Traditional photolithography is struggling to reach the required critical dimensions. This study investigates the potential of using I-PFC12 as a way to produce contrast between the growth area and non-growth areas of a surface subsequent to extreme ultraviolet (EUV) exposure. Once exposed to EUV, the I-PFC12 molecule should degrade with the help of the photocatalytic substrate, allowing for the subsequent selective deposition of the hard mask. The stability of a vapor-deposited I-PFC12 self-assembled monolayer (SAM) was examined when exposed to ambient light for extended periods of time by using X-ray photoelectron spectroscopy (XPS). Two substrates, SiO₂ and TiO₂, are investigated to ascertain the suitability of using TiO₂ as a photocatalytic active substrate. Following one month of exposure to light, the atomic concentrations showed a more substantial fluorine loss of 10.2% on the TiO₂ in comparison to a 6.2% loss on the SiO₂ substrate. This more pronounced defluorination seen on the TiO₂ is attributed to its photocatalytic nature. Interestingly, different routes to degradation were observed for each substrate. Reference samples preserved in dark conditions with no light exposure for up to three months show little degradation on the SiO₂ substrate, while no change is observed on the TiO₂ substrate. The results reveal that the I-PFC12 SAM is an ideal candidate for resistless EUV lithography. Full article

A hydraulic support is one of the most important pieces of equipment in fully mechanized coal mining, and its stability and reliability will have a direct impact on fully mechanized coal mining. In order to deeply elucidate the dynamic working characteristics of a hydraulic support during lifting, lowering, and moving, and to provide theoretical support for further optimizing the stability and reliability of a hydraulic support, the dynamic characteristics of a hydraulic support are studied in this paper. Firstly, in order to study the dynamic working characteristics of hydraulic support lifting, a rigid–flexible coupling dynamic simulation model of a hydraulic support is established; in order to study the dynamic working characteristics of hydraulic support moving, a microcontact dynamic model of a hydraulic support and the caving face roof and floor based on G-W contact theory is proposed, and the first rigid–flexible–mechanical–hydraulic coupling dynamic simulation system of a hydraulic support and the roof and floor of a caving face is established in the industry. Then, based on this foundation, simulation experiments are conducted for hydraulic support lifting, moving without pressure, and moving with pressure, respectively. The working characteristic parameters of the hydraulic support are collected and analyzed. The results show that working speed, working height, surface contact conditions, residual working resistance, and impact load have different effects on the stability and reliability of the hydraulic support. This study can provide in-depth technical support and theoretical guidance for understanding and improving the dynamic working characteristics of the hydraulic support. Full article

Microelectromechanical systems (MEMS) ohmic contact switches are considered to be a promising candidate for wireless communication applications. The longevity of MEMS switches is directly related to the reliability and performance of microcontacts. In this work, an improved microcontact test fixture with high actuation rates (KHz) and highly precise position control (nm) and force (nN) control was developed. Here, we collected microcontact performance data from initial contact tests (ICT) and microcontact reliability data from cold switched tests (CST). To perform these tests with our test fixture, we fabricated MEMS microcontact test structures with relatively high Young’s modulus electroplated Nickel (Ni)-based, fixed–fixed beam structure with Au/RuO₂ bimetallic microcontacts. These structures were characterized for forces ranging from 200–1000 µN in ICT tests. In a CST test, the tested microcontact survived more than 200 million cycles at a 1 KHz cycle rate, with a stable contact resistance value ranging between 3.8–5.2 Ω. These experiments validate the potentiality of our microcontact test fixture, and will facilitate further investigation on advanced microcontacts to enhance the MEMS switch’s reliability. Full article