Search Results (689)

This study assesses the quality of financial reporting in ten Central and Eastern European countries using a methodology based on natural language processing (NLP) techniques. 570 annual reports of companies listed on the main index on the stock exchanges of 10 Central and Eastern European (CEE) countries, over the period 2019–2023, were evaluated to determine the degree of convergence of the following four measurable qualitative characteristics: relevance, exact representation, comparability and understandability. The main objective is to identify consistency in the quality of accounting information based on the application of an international financial reporting framework. The applied methodology eliminates subjective variability by implementing a standardized scoring system, aligned with the criteria developed by NiCE, using libraries such as spaCy and NLTK for term extraction, respective sentiment analysis and word frequency evaluation. The results reveal significant heterogeneity in all characteristics examined, with statistical tests confirming substantial differences between countries. The investigation of relevance revealed partial convergence, with three dimensions achieving complete uniformity, while the exact representation showed the highest variability. The assessment of comparability showed a significant difference between countries’ extreme values, and in terms of comprehensibility a formalistic approach was evident, with technical dimensions outweighing user-oriented aspects. The overall quality index varied significantly across countries, with a notable average deterioration in 2023, indicating structural vulnerabilities in financial reporting systems. These findings support initial hypotheses on the lack of homogeneity in the quality of financial reporting in the selected region, despite the implementation of international standards. Full article

The 1.9 billion metric tons of steel globally manufactured in 2023 justify the steel industry’s pivotal role in modern society’s growth. Considering the rapid development of countries that have not fully taken part in the global market, such as Africa, steel production is expected to increase in the next decade. However, the environmental burden associated with steel manufacturing must be mitigated to achieve sustainable production, which would align with the European Green Deal pathway. Such a burden is associated both with the GHG emissions and with the solid residues arising from steel manufacturing, considering both the integrated and electrical routes. The valorisation of the main steel residues from the electrical steelmaking is the central theme of this work, referring to the steel electric manufacturing in the Dalmine case study. The investigation was carried out from two different points of view, comprising the action of a plasma electric reactor and a RecoDust unit to optimize the recovery of iron and zinc, respectively, being the two main technologies envisioned in the EU-funded research project ReMFra. This work focuses on those preliminary steps required to detect the optimal recipes to consider for such industrial units, such as thermodynamic modelling, testing the mechanical properties of the briquettes produced, and the smelting trials carried out at pilot scale. However, tests for the usability of the dusty feedstock for RecoDust are carried out, and, with the results, some recommendations for pretreatment can be made. The outcomes show the high potential of these streams for metal and mineral recovery. Full article

Traffic-related pollutants remain a challenging global issue, with significant policy implications. Within the European Union, Romania has the highest yearly societal cost per capita due to air pollution, which kills 29,000 Romanians every year, whereas the health and economic costs are also significant. In this context, municipal authorities in the country, particularly in high-density areas, should place a strong focus on mitigating air pollution. In particular, the capital city, Bucharest, ranks among the most congested cities in the world while registering the highest pollution index in Romania, with traffic pollution responsible for two-thirds of its air pollution. Consequently, studies that assess and model pollution trends are paramount to inform local policy-making processes and assist pollution-mitigation efforts. In this paper, a generalized additive modeling (GAM) framework is employed to model hourly concentrations of nitrogen dioxide (NO₂), i.e., a relevant traffic-pollution proxy, at a busy urban traffic location in central Bucharest, Romania. All models are developed on a wide, fine-granularity dataset spanning January 2017–December 2022 and include extensive meteorological covariates. Model robustness is assured by switching between the generalized additive model (GAM) framework and the generalized additive mixed model (GAMM) framework when the residual autoregressive process needs to be specifically acknowledged. Results indicate that trend GAMs explain a large amount of the hourly variation in traffic pollution. Furthermore, meteorological factors contribute to increasing the models’ explanation power, with wind direction, relative humidity, and the interaction between wind speed and the atmospheric pressure emerging as important mitigators for NO₂ concentrations in Bucharest. The results of this study can be valuable in assisting local authorities to take proactive measures for traffic pollution control in the capital city of Romania. Full article

The measurement of national well-being has become central to both academic and policy debates, particularly within the framework of sustainable development. In this context, this study investigates the relationship between macroeconomic conditions and subjective well-being in Portugal. Using annual data from 2004 to 2022, we explore the effects of GDP per capita, unemployment, and inflation on the Global Well-Being Index (GWBI). Employing ordinary least squares (OLS) regression, the results indicate a significant positive relationship between GDP per capita and subjective well-being, while inflation is negatively associated. Contrary to expectations, the unemployment rate showed a positive and significant association with the GWBI. This counterintuitive result may reflect institutional buffering effects, such as social safety nets, strong family structures, or lagged responses in perceptions of well-being. Similar patterns were observed in other southern European countries with strong informal social support systems. These findings contribute to a deeper understanding of how economic indicators relate to perceived well-being, particularly in the context of a southern European country. The study offers relevant insights for public policy, including the alignment of macroeconomic management with the Sustainable Development Goals (SDGs), especially SDG 3 (Good Health and Well-being) and SDG 8 (Decent Work and Economic Growth). Full article

This study investigates how differing national research governance models impact academic performance by comparing European Research Council (ERC) grant winners in the social sciences and humanities from France and the Netherlands. Situated within the broader context of centralized versus decentralized research systems, the analysis aims to understand how these structures shape publication trends, thematic diversity, and collaboration patterns. Drawing on Scopus and SciVal data covering 9996 publications by 305 ERC winners between 2019 and 2023, we employed a multi-method approach, including latent Dirichlet allocation for topic modeling, compound annual growth rate analysis, and co-authorship network analysis. The results show that neuroscience, climate change, and psychology are dominant domains, with language and linguistics particularly prevalent in France and law and political science in the Netherlands. French ERC winners are more likely to be affiliated with national or sectoral institutions, whereas in the Netherlands, elite universities dominate. Collaboration emerged as a key success factor, with an average of four co-authors per publication and network analyses revealing central figures who bridge topical clusters. International collaborations were consistently linked with higher visibility, while single-authored publications showed limited impact. These findings suggest that institutional context and collaborative practices significantly shape research performance in both countries. Full article

As global climate change intensifies and the transition to clean energy accelerates, lithium-ion batteries—critical components of electric vehicles—are becoming increasingly vital in international trade networks. This study investigates the structural evolution and determinants of the electric vehicle lithium-ion battery trade network among European Union (EU) member states from 2012 to 2023, employing social network analysis and the multiple regression quadratic assignment procedure method. The findings demonstrate the transformation of the network from a centralized and loosely connected structure, with Germany as the dominant hub, to a more interconnected and decentralized system in which Poland and Hungary emerge as the leading players. Key network metrics, such as the density, clustering coefficients, and average path lengths, reveal increased regional trade connectivity and enhanced supply chain efficiency. The analysis identifies geographic and economic proximity, logistics performance, labor cost differentials, energy resource availability, and venture capital investment as significant drivers of trade flows, highlighting the interaction among spatial, economic, and infrastructural factors in shaping the network. Based on these findings, this study underscores the need for targeted policy measures to support Central and Eastern European countries, including investment in logistics infrastructure, technological innovation, and regional cooperation initiatives, to strengthen their integration into the supply chain and bolster their export capacity. Furthermore, fostering balanced inter-regional collaborations is essential in building a resilient trade network. Continued investment in transportation infrastructure and innovation is recommended to sustain the EU’s competitive advantage in the global electric vehicle lithium-ion battery supply chain. Full article

Renewable energy stands as a pivotal solution to environmental concerns, prompting substantial research and development endeavors to promote its adoption and enhance energy efficiency. Despite the recognized environmental superiority of renewable energy systems, there is a lack of globally standardized indicators specifically focused on renewable energy efficiency. This study aims to develop and apply a non-parametric data envelopment analysis (DEA) indicator, termed the Renewable Energy Indicator (REI), to measure environmental performance at the national level and to identify differences in renewable energy efficiency across countries grouped by development status and income level. The REI incorporates new factors such as agricultural methane emissions (thousand metric tons of ${\mathrm{CO}}_2$ equivalent), PM2.5 air pollution exposure (µg/m³), and aspects related to electricity, including consumption (as % of total final energy consumption), production from renewable sources, excluding hydroelectric (kWh), and accessibility in rural and urban areas (% of population with access), aligning with the emerging paradigm outlined by the United Nations. By segmenting the REI into global, developmental, and income group classifications, this study conducts the Mann–Whitney U test and the Kruskal–Wallis H tests to identify variations in renewable energy efficiency among different country groups. Our findings reveal top-performing countries globally, highlighting both developed (e.g., Sweden) and developing nations (e.g., Costa Rica, Sri Lanka). Central and North European countries demonstrate high efficiency, while those facing political and economic instability perform poorly. Agricultural-dependent nations like Australia and Argentina exhibit lower REI due to significant methane emissions. Disparities between developed and developing markets underscore the importance of understanding distinct socio-economic dynamics for effective policy formulation. Comparative analysis across income groups informs specific strategies tailored to each category. Full article

Guaranteeing food safety in the European Union (EU) is a continuing issue affected by diverse national traditions, regulatory power, and consumer culture. Despite the presence of a harmonized regulatory context, there continues to be variability in performance among the 27 member states. This study gives an extensive comparative evaluation of EU food safety based on three indicators: Rapid Alert System for Food and Feed (RASFF) alerts, pesticide maximum-residue-limit (MRL) violation, and per capita food loss. Fuzzy TOPSIS, K-means clustering, and scenario-based sensitivity tests are used to give an extensive appraisal of the performance of member states. Alarming differences are quoted as findings of significance. The highest number of RASFF notifications (212) and percentage of pesticide MRL non-compliance (1.5%) were reported in 2022 by Bulgaria, whereas the lowest values were reported by Estonia and Lithuania—15–20 RASFF notifications and less than 0.6% MRL violation rates. A statistically significant correlation (r = 0.72, p < 0.001) between pesticide MRL violation and food safety warnings was confirmed in favor of pesticide regulation as the optimal predictor of food safety warnings. On the other hand, food loss did not significantly affect safety measures but indicated very high variation (from 76 kg/capita per year in Croatia to 142 kg/capita per year in Greece). These findings suggest that while food loss remains an environmental problem, pesticide control is more central to the protection of food safety. Targeted policy is what the research necessitates: intervention and stricter enforcement in low-income countries, and diffusion of best practice from successful states. The composite approach adds to EU food safety policy discourse through the combination of performance indicators and targeted regulatory emphasis. Full article

Using innovative and sustainable materials has become crucial for developed countries. Reusing waste as a secondary raw material in industrial processes central to the circular economy could enhance environmental sustainability and support local economies. Building materials such as Portland cement have a significant environmental impact due to greenhouse gas emissions and construction and demolition waste (CDW), which is challenging to recycle. Research into sustainable alternatives is, therefore, essential. The European Union has set ambitious targets to reduce greenhouse gas emissions by 55% by 2030 and achieve climate neutrality by 2050. The National Recovery and Resilience Plan (PNRR) supports the green transition in Italy by promoting sustainable materials like geopolymers. These ceramic-like materials are based on aluminosilicates obtained through the chemical activation of waste rich in silica and aluminosilicate compounds. Though promising, these materials require further research to address challenges like long-term durability and chemical variability. Collaboration between scientific research and industry is essential to develop specific protocols and suitable infrastructures. This article provides a critical review of the advancements and challenges in using alkali-activated waste as construction binders, focusing on Italy, and encourages the exploration of alternative sustainable materials beyond conventional Portland cement. Full article

Equine piroplasmosis (EP) is an endemic parasitic disease in southern European countries, such as Spain. Andalusia, the most southwestern region of Europe, is the community with the highest number of registered horses and farms in Spain and one of the main international exporters of Andalusian (Spanish Purebred) horses worldwide. Considering the current expansion of this disease and the possible effect of climate change on its prevalence, studying the EP prevalence in this region is compelling. Molecular (PCR) and serological methods (cELISA and IFAT) were used to study the true and apparent prevalences during a period of three consecutive years, evaluating the effects of age, sex, season, year of testing, and province. Results showed different EP prevalences between western and eastern provinces, as well as among seasons. Moreover, a positive association was observed between age and T. equi seropositivity, without any effect of sex. Our findings demonstrate that Andalusia is an EP endemic region, but prevalences were lower compared to central and northern Spanish regions. Moreover, EP prevalence has not increased in Andalusia in recent years despite climate changes. Full article

Starting Active Materials for Synthesis (SAMS) represents a critical stage in drug manufacturing, directly influencing the microbiological quality and safety of the final product. The introduction of SAMS marks the point where Good Manufacturing Practices (GMP) begin to apply, which are essential for ensuring sterility and preventing microbial contamination during the synthesis process. However, defining the exact point in the process that qualifies as the SAMS is subject to uncertainties, as earlier stages are not always governed by stringent GMP standards. The regulatory differences between various countries further contribute to this issue. This study explores the implications of SAMS selection and use in relation to sterility and infection control, analyzing the guidelines of major Regulatory Authorities and comparing their approaches to GMP. Regulations from several international regulatory agencies were examined, with a particular focus on microbiological control measures and infection protection in the SAMS manufacturing process. The analysis focused on the microbiological control requirements and safety measures applicable to the stages preceding the introduction of SAMS into the production of the final Active Pharmaceutical Ingredients (APIs). Documents published between 2015 and 2025 were included based on predefined criteria regarding relevance, accessibility, and regulatory authority. The analysis revealed significant discrepancies between regulations regarding the definition and management of SAMS. In particular, the regulations in Mexico and India have notable gaps, failing to provide clear guidelines on SAMS sterility and protection against infectious contamination. Conversely, China has introduced risk-based approaches and early-stage microbiological controls, especially for sterile products, aligning with international standards. The European Medicines Agency (EMA), the U.S. Food and Drug Administration (FDA), the Pharmaceutical Inspection Co-operation Scheme (PIC/S), and the World Health Organization (WHO) have well-established systems for microbiological quality control of SAMS, including rigorous measures for the validation of suppliers and risk management to ensure that SAMS does not compromise the microbiological safety of the final product. The regulations in Brazil and Canada introduce additional measures to protect the microbiological quality of SAMS, with specifications for contamination control and certification of critical stages. The lack of a harmonized language for the definition of SAMS, coupled with a fragmented regulatory framework, presents a challenge for infection protection in pharmaceutical manufacturing. Key issues include the absence of specific regulations for stages prior to the introduction of SAMS and the lack of standards for inspections related to these stages. A desirable solution would be the mandatory extension of GMPs to the stages before SAMS introduction, with centralized control to ensure sterility and protection against infection throughout the entire manufacturing process. Full article

Nature-based solutions (NBS) have attracted increasing attention in local air quality and climate change adaptation plans as suitable measures to reduce health risks. Although several studies have reported health benefits from short-term urban cooling effects of NBS, medium- to long-term health benefits are still poorly understood. In this study, we assess the changes in long-term mortality related to temperature fluctuations induced by city-scale vegetation actuations in three Southern European cities. We performed two annual high-resolution simulations with the Weather Research and Forecasting model to anticipate the impact of future revegetation strategies on temperature in these urban areas. Further, we assessed the impact of temperature changes on health using a country-specific minimum mortality temperature (MMT) reported in scientific literature. It was found that NBS could provide non-negligible reductions of long-term mortality related to temperature regulation (central estimate of 4.1, 1.2, and 3.4 cases avoided per year in Madrid, Milano, and Bologna, respectively). The effect of vegetation is site-dependent, and the cooling effect explains most of the benefits, especially in densely built-up areas of the cities analyzed. Future research should combine short/long-term temperature effects with other indirect implications (air quality, mental health) in the context of climate change. Full article

In response to the escalating challenges of climate change and the urgent need to reduce greenhouse gas emissions, the energy transition has become a central priority of environmental policy worldwide. The European Union (EU), a global leader in implementing sustainable energy solutions, has pursued numerous initiatives aimed at advancing energy transformation. This paper presents the results of an empirical study assessing the efficiency of the energy transition process in the EU-27 countries over the 2013–2023 period. The assessment is based on the dynamic changes in selected indicators relevant to the energy transition, including decarbonization of the energy sector, improvements in energy efficiency, the share of renewable energy sources, energy import dependency, greenhouse gas emissions, and the extent of energy poverty. A multidimensional analysis was conducted using a specially developed energy transition efficiency index, where indicator weights were determined through the Analytic Hierarchy Process. The study also examined two distinct sub-periods (2013–2018 and 2018–2023), as well as a series of shorter, two-year intervals (2013–2015, 2015–2017, 2017–2019, 2019–2021, and 2021–2023), enabling a more nuanced analysis of the temporal evolution of transition efforts. Additionally, principal component analysis was employed to classify the EU-27 countries based on the similarity of their energy transition profiles. The findings reveal significant disparities in the pace and scope of energy transition across member states. Luxembourg, Malta, and the Netherlands demonstrated the most dynamic progress during the study period, followed by Sweden, Denmark, Germany, and Estonia. In contrast, Bulgaria, Hungary, Poland, Latvia, Croatia, and Romania recorded the lowest performance. These differences underscore the varying starting points, policy approaches, and implementation speeds among EU countries in achieving energy transition objectives. Full article

With the European Union (EU) Health Technology Assessment (HTA) regulation, Joint Clinical Assessments (JCA) are now required for oncological and advanced therapy medicinal products. The JCA assessment scope is determined through the PICO framework (Population, Intervention, Comparator, Outcome). Given the tight JCA timelines, Health Technology Developers (HTD) must anticipate PICO elements early to prepare dossiers effectively. This study investigates whether PICO can be predicted across EU member states using publicly available information. A systematic literature review was conducted to identify relevant peer-reviewed articles. Additionally, an extensive search of publicly available HTA documents, including reports, methodological guidelines, submission templates, and market access information was performed across 29 European countries. Relevant information for PICO anticipation was extracted. For many member states, a wealth of relevant information is publicly accessible: 66% have HTA reports publicly available, 79% have HTA methodological guidelines, 69% have dossier templates, and 100% have market access status lists. Between countries, the requirements for population and outcomes are largely aligned, making comparator the central element in PICO anticipation. PICO can be anticipated reliably based on public information. HTDs must be prepared to adjust their strategies as national procedures adapt, ensuring alignment with both current and emerging EU and national requirements. Full article

Background: Penile cancer is an uncommon malignancy in European and North America countries, accounting for less than 1% of malignant neoplasms. The etiology of penile cancer involves a complex interplay of clinical and behavioral factors, including phimosis, smoking, excess body weight, and HPV infection. The significance of these factors varies according to geographical and socioeconomic contexts. A comprehensive understanding of these interactions is essential for developing targeted prevention strategies and improving outcomes across diverse populations. However, the majority of existing studies originate from South America or Africa; there is a lack of data regarding these associations and prognoses in European populations, particularly in Central Europe, including Poland. Objectives: This study aimed to investigate the prevalence of well-established clinical and behavioral characteristics associated with penile cancer and their influence on penile cancer prognosis in a cohort of 153 patients who underwent surgical intervention at a single tertiary medical center in Central Europe. Materials and Methods: This retrospective study was conducted from October 2011 to October 2024 at a single tertiary medical center and included 153 patients who underwent surgical treatment for penile cancer during this period. Demographic and histopathological data were collected. A comprehensive, self-administered patient survey was conducted to identify the presence of potentially relevant clinical and lifestyle characteristics. Moreover, the prevalence of human papillomavirus (HPV) in penile cancer specimens was determined using p16 immunohistochemistry. Results: The median age of the participants in the study was 64 years (range: 30–87). The predominant identified features were phimosis (47.06%), residence in small agglomerations (43.14%), obesity (43.14%), overweight (40.52%), and smoking (38.56%). HPV infection was detected in only 14.38% of the patients. Phimosis was associated with a more locally advanced penile cancer stage (T-stage). The stage of the primary tumor, lymph node involvement, and histopathological grading significantly affected patient survival, with a poorer prognosis observed in more advanced stages and associated with poorly differentiated histopathological features. Among all the examined clinical and lifestyle characteristics, only smoking demonstrated a significant two-fold higher risk of mortality and was associated with a significantly lower overall survival compared to the absence of smoking (p = 0.047). Conversely, human papillomavirus (HPV) infection was associated with a six-fold reduction in the risk of death (p = 0.063). Conclusions: Phimosis was the most frequently observed clinical characteristic in our cohort study and was correlated with a more advanced penile cancer tumor stage. Smoking was associated with lower rates of patient survival, while HPV-positive patients demonstrated a trend toward lower mortality compared to HPV-negative patients. Full article