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Review

1,514 Views

15 Pages

The Added Benefits of Performing Liver Tumor Ablation in the Angiography Suite: A Pictorial Essay of Combining C-Arm CT Guidance with Hepatic Arteriography for Liver Tumor Ablation

Niek Wijnen,
Khalil Ramdhani,
Rutger C. G. Bruijnen,
Hugo W. A. M. de Jong,
Pierleone Lucatelli and
Maarten L. J. Smits

Cancers2025, 17(14), 2330;https://doi.org/10.3390/cancers17142330

14 July 2025

The HepACAGA (Hepatic Arteriography and C-arm CT-Guided Ablation) technique, which integrates C-arm CT guidance with transcatheter C-arm CT hepatic arteriography (C-arm CTHA), significantly improves liver tumor ablation outcomes by enhancing tumor vi...

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Article

15 Pages

Improved Detection of Small (<2 cm) Hepatocellular Carcinoma via Deep Learning-Based Synthetic CT Hepatic Arteriography: A Multi-Center External Validation Study

Jung Won Kwak,
Sung Bum Cho,
Ki Choon Sim,
Jeong Woo Kim,
In Young Choi and
Yongwon Cho

Diagnostics2026, 16(2), 343;https://doi.org/10.3390/diagnostics16020343

21 January 2026

Background/Objectives: Early detection of hepatocellular carcinoma (HCC), particularly small lesions (<2 cm), which is crucial for curative treatment, remains challenging with conventional liver dynamic computed tomography (LDCT). We aimed to deve...

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Article

9 Citations

2,665 Views

13 Pages

Conventional versus Hepatic Arteriography and C-Arm CT-Guided Ablation of Liver Tumors (HepACAGA): A Comparative Analysis

Niek Wijnen,
Rutger C. G. Bruijnen,
Evert-Jan P. A. Vonken,
Hugo W. A. M. de Jong,
Joep de Bruijne,
Guus M. Bol,
Jeroen Hagendoorn,
Martijn P. W. Intven and
Maarten L. J. Smits

Cancers2024, 16(10), 1925;https://doi.org/10.3390/cancers16101925

18 May 2024

Purpose: Hepatic Arteriography and C-Arm CT-Guided Ablation of liver tumors (HepACAGA) is a novel technique, combining hepatic–arterial contrast injection with C-arm CT-guided navigation. This study compared the outcomes of the HepACAGA techniq...

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Opinion

11 Citations

2,982 Views

13 Pages

The Added Value of Transcatheter CT Hepatic Angiography (CTHA) Image Guidance in Percutaneous Thermal Liver Ablation: An Experts’ Opinion Pictorial Essay

Robbert S. Puijk,
Madelon Dijkstra,
Susan van der Lei,
Hannah H. Schulz,
Danielle J. W. Vos,
Florentine E. F. Timmer,
Bart Geboers,
Hester J. Scheffer,
Jan J. J. de Vries and
Martijn R. Meijerink
+ 5 authors

Cancers2024, 16(6), 1193;https://doi.org/10.3390/cancers16061193

18 March 2024

With the rapidly evolving field of image-guided tumor ablation, there is an increasing demand and need for tools to optimize treatment success. Known factors affecting the success of (non-)thermal liver ablation procedures are the ability to optimize...

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Article

3 Citations

2,399 Views

12 Pages

Ablation of Small Liver Metastases Presenting as Foci of Diffusion Restriction on MRI–Results from the Prospective Minimally Invasive Thermal Ablation (MITA) Study

Niek Wijnen,
Rutger C. G. Bruijnen,
Annelou A. B. Thelissen,
Hugo W. A. M. de Jong,
Rachel S. van Leeuwaarde,
Jeroen Hagendoorn,
Guus M. Bol and
Maarten L. J. Smits

Cancers2024, 16(13), 2409;https://doi.org/10.3390/cancers16132409

29 June 2024

Purpose: Liver metastases presenting as small hyperintense foci on diffusion-weighted imaging (DWI) pose a therapeutic challenge. Ablation is generally not possible since these lesions are often occult on ultrasound and CT. The purpose of this prospe...

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