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22 Citations

6,843 Views

17 Pages

Down Regulation of CIAPIN1 Reverses Multidrug Resistance in Human Breast Cancer Cells by Inhibiting MDR1

Dan Lu,
Zhibo Xiao,
Wenxiu Wang,
Yuqing Xu,
Shujian Gao,
Lili Deng,
Wen He,
Yu Yang,
Xiaofei Guo and
Xuemei Wang

Molecules2012, 17(6), 7595-7611;https://doi.org/10.3390/molecules17067595

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20 June 2012

Cytokine-induced apoptosis inhibitor 1 (CIAPIN1), initially named anamorsin, a newly indentified antiapoptotic molecule is a downstream effector of the receptor tyrosine kinase-Ras signaling pathway. Current study has revealed that CIAPIN1 may have w...

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Article

3 Citations

3,067 Views

19 Pages

Prediction of CIAPIN1 (Cytokine-Induced Apoptosis Inhibitor 1) Signaling Pathway and Its Role in Cholangiocarcinoma Metastasis

Son Dinh An Truong,
Molin Wongwattanakul,
Tanakorn Proungvitaya,
Temduang Limpaiboon,
Sittiruk Roytrakul,
Daraporn Chua-on,
Doungdean Tummanatsakun and
Siriporn Proungvitaya

J. Clin. Med.2022, 11(13), 3826;https://doi.org/10.3390/jcm11133826

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1 July 2022

Cholangiocarcinoma (CCA), a malignancy of the biliary epithelium, can arise at any point in the biliary system. We previously reported that CIAPIN1 is detectable in the sera and that its overexpression was associated with poor prognosis and metastasi...

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Article

622 Views

17 Pages

Sulfatide Acts as a Regulatory Molecule Controlling β1 Integrin–STAT5 Signaling and BOLA2-Dependent Apoptotic Pathway in Breast Cancer Cells

Jaroslaw Suchanski,
Weronika Woldanska,
Adam Sciana,
Barbara Suchanska and
Leszek Moniakowski

Int. J. Mol. Sci.2025, 26(24), 11873;https://doi.org/10.3390/ijms262411873

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9 December 2025

Cell membrane glycosylations play a critical role in regulating cell signaling, adhesion, and immune recognition. Abnormal glycosylation is a hallmark of cancer and promotes tumor progression. Sulfatide (SM4), a glycosphingolipid synthesized by galac...

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