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3 Results Found

  • Article
  • Open Access
3 Citations
3,387 Views
15 Pages

Synthesis, Analytical Characterization, and Human CB1 Receptor Binding Studies of the Chloroindole Analogues of the Synthetic Cannabinoid MDMB-CHMICA

  • Sascha Münster-Müller,
  • Steven Hansen,
  • Tobias Lucas,
  • Arianna Giorgetti,
  • Lukas Mogler,
  • Svenja Fischmann,
  • Folker Westphal,
  • Volker Auwärter,
  • Michael Pütz and
  • Till Opatz

6 November 2024

Synthetic cannabinoids (SCs) are one of the largest groups of new psychoactive substances (NPSs). However, the relationship between their chemical structure and the affinity to human CB1 receptors (hCB1), which mediates their psychotropic activity, i...

  • Systematic Review
  • Open Access
14 Citations
7,039 Views
24 Pages

Detection of the Synthetic Cannabinoids AB-CHMINACA, ADB-CHMINACA, MDMB-CHMICA, and 5F-MDMB-PINACA in Biological Matrices: A Systematic Review

  • Elisabet Navarro-Tapia,
  • Jana Codina,
  • Víctor José Villanueva-Blasco,
  • Óscar García-Algar and
  • Vicente Andreu-Fernández

23 May 2022

New synthetic cannabinoids (SCs) are emerging rapidly and continuously. Biological matrices are key for their precise detection to link toxicity and symptoms to each compound and concentration and ascertain consumption trends. The objective of this s...

  • Systematic Review
  • Open Access
41 Citations
18,908 Views
17 Pages

Toxicity of Synthetic Cannabinoids in K2/Spice: A Systematic Review

  • Mariana Campello de Oliveira,
  • Mariana Capelo Vides,
  • Dângela Layne Silva Lassi,
  • Julio Torales,
  • Antonio Ventriglio,
  • Henrique Silva Bombana,
  • Vilma Leyton,
  • Cintia de Azevedo-Marques Périco,
  • André Brooking Negrão and
  • João Maurício Castaldelli-Maia
  • + 1 author

(1) Background: Synthetic cannabinoids (SCs) are emerging drugs of abuse sold as ‘K2’, ‘K9’ or ‘Spice’. Evidence shows that using SCs products leads to greater health risks than cannabis. They have been associated...