Search Results (890)

The increasing global demand for clean hydrogen necessitates production methods that minimize greenhouse gas emissions while being scalable and economically viable. Hydrogen has a very high gravimetric energy density of about 142 MJ/kg, which makes it a very promising energy carrier for many uses, such as transportation, industrial processes, and fuel cells. Methane pyrolysis has emerged as an attractive low-carbon alternative, decomposing methane (CH₄) into hydrogen and solid carbon while circumventing direct CO₂ emissions. Still, the process is very endothermic and has always depended on fossil-fuel heat sources, which limits its ability to run without releasing any carbon. This review examines the integration of geothermal energy and methane pyrolysis as a sustainable heat source, with a focus on Enhanced Geothermal Systems (EGS) and Closed-Loop Geothermal (CLG) technologies. Geothermal heat is a stable, carbon-free source of heat that can be used to preheat methane and start reactions. This makes energy use more efficient and lowers operating costs. Also, using flared natural gas from remote oil and gas fields can turn methane that would otherwise be thrown away into useful hydrogen and solid carbon. This review brings together the most recent progress in pyrolysis reactors, catalysts, carbon management, geothermal–thermochemical coupling, and techno-economic feasibility. The conversation centers on major problems and future research paths, with a focus on the potential of geothermal-assisted methane pyrolysis as a viable way to make hydrogen without adding to the carbon footprint. Full article

Invertebrates are increasingly consumed and kept as pets, research models, and in zoological exhibits, creating a growing need to better understand their clinical management and welfare. However, the knowledge regarding nociception, pain perception, and euthanasia in invertebrates remains limited, and standardized protocols are largely absent. Current guidelines are incomplete, often anecdotal, and omit several major invertebrate phyla. To address this gap, we conducted a narrative review of the literature, aiming to critically evaluate existing euthanasia methods, associated welfare implications, and opportunities for refinement. The amount of peer-reviewed species-specific literature is limited and scattered. In addition, most described methods are insufficiently studied and/or do not align with our definition of euthanasia. Based on the available literature, and to provide practical guidance despite these limitations, we propose a two-step approach to invertebrate euthanasia. The first step consists of inducing anesthesia to achieve loss of responsiveness, followed by a second step; a terminal procedure involving physical or chemical destruction of the brain or major ganglia. Our review focuses on the application of this two-step approach. The effectiveness and humaneness of euthanasia techniques vary considerably across taxa and life stages. Substantial further research is required to validate and optimize humane end-of-life procedures for diverse invertebrate species. Full article

Background/Objectives: African American women are less likely to breastfeed in general and to breastfeed exclusively for the first six months of infancy. Racial and ethnic breastfeeding disparities are especially pronounced in the South, particularly in rural communities. These differences are attributed largely to structural lactation impediments that include less breastfeeding support in healthcare settings, workplaces, and communities. While a great deal of research has explored racial differences in breastfeeding, minimal attention has been paid to the social correlates and racial disparities associated with the 2022 U.S. infant formula shortage. Our study explores racial distinctions in the formula shortage’s effect on breastfeeding support among Gulf Coast Mississippians. Methods: We use data from the second wave of the Mississippi REACH (Racial and Ethnic Approaches to Community Health) Social Climate Survey to determine if racial differences are evident in the formula shortage’s influence on breastfeeding support. We predict that the infant formula shortage will have prompted African American respondents to become much more supportive of breastfeeding than their White counterparts, net of sociodemographic controls. This hypothesis is based on the lower prevalence of exclusive breastfeeding among African Americans, thereby indicating a greater reliance on formula. The study uses a general population (random digit dial) sample and purposive (exclusively African American) oversample to analyze validated data from a cross-sectional survey. Sampling took place between September and December 2023, with a sample population of adult male and female Mississippians. A series of binary logistic regression models were employed to measure the association of race with breastfeeding support changes resulting from the infant formula shortage. Results: The study results support the hypothesis, as seen by a positive association between African Americans and increased breastfeeding support directly related to the infant formula shortage. Further, the baseline statistical model reveals African American respondents to be five times more likely than White respondents (p < 0.001) to report that the formula shortage increased their support of breastfeeding. Conclusions: We conclude by discussing this study’s implications and promising directions for future research. Full article

This study investigates the measurement bias introduced by the widespread use of overlapping returns in time series momentum (TSM) research, which can materially overstate the strength of TSM signals. Using a univariate AR(1) framework, simulations, and S&P 500 and S&P/ASX 200 index data from 1996 to 2019, we link TSM strength to return autocorrelation, volatility and the look-back horizon under both overlapping and non-overlapping return constructions. The analysis shows that overlapping returns mechanically accumulate autocorrelation, generating the familiar monotonic increase in measured TSM strength as the look-back period lengthens. Empirically, we find that return autocorrelation is the dominant driver of measured TSM strength and that the monotonic look-back profile becomes weaker and less systematic when non-overlapping returns are used. The AR(1) framework predicts a negative relation between volatility and TSM strength, and we observe this sign in both markets, but the estimated effects are not statistically significant at conventional levels. These results highlight the risk that overlapping returns artificially inflate momentum signals, with implications for backtesting robustness and portfolio risk management. Full article

Nobel Laureate Markowitz originates portfolio selection as the birth of modern finance. Nobel Laureate Sharpe implements portfolio selection and originates capital asset pricing models. Nobel Laureate Fama also implements portfolio selection and originates zero-covariance capital asset pricing models. After these feats, researchers have gradually realized additional objectives and have promisingly extended portfolio selection into multiple-objective portfolio selection. However, there hardly exists research to leap from multiple-objective portfolio selection to multiple-objective capital asset pricing models (as initiated by Markowitz and Sharpe in finance). Moreover, the extension is basically confined to the branches of mathematics, operations research, optimization, and computer sciences. Many researchers sufficiently review multiple-objective portfolio selection. However, the reviews are extensive. Instead, we intensively criticize and envision the research on multiple-objective portfolio selection from the perspective of capital asset pricing models by crystallizing the research limitations and heralding future directions. Specifically, we emphasize seven research limitations for multiple-objective portfolio optimization, multiple-objective capital asset pricing models, and multiple-objective zero-covariance capital asset pricing models. We also generalize from common three-objective portfolio selection to k-objective portfolio selection. Visually, we orchestrate figures to delineate the complexity. Theoretically, this paper heralds challenging but encouraging future directions. Pragmatically, this paper proposes a formulation for the multiple-objective nature of practical convolution in finance. Full article

Background/Objectives: A stem cell therapy for type 1 diabetes (T1D) is experimentally available but only to those few humans in whom the use of systemic immunosuppression can be justified. For others with T1D, a means to deliver the islets needs to be perfected. We have previously bioengineered a removable device for this purpose and now wish to test the effect of adding extracellular matrix (ECM) derived from decellularised human pancreas to it. Methods: The complete device consists of encapsulated pluripotent stem cell differentiated islets seeded into tubular scaffolds of polycaprolactone made by melt electrospin writing and to which ECM was added. The seeded device was implanted either subcutaneously (SC) or intraperitoneally (IP) into streptozotocin diabetic immunodeficient mice. The outcome over the next few months was compared with that achieved in diabetic mice implanted IP with encapsulated islets alone. Results: The device seeded with encapsulated islets but not containing ECM functioned less well than encapsulated islets implanted alone, with lower human C-peptide production. However, when ECM was added to the seeded device and whether implanted SC or IP, islets functioned as efficiently as those implanted without use of a scaffold. Conclusions: These data provide optimism for the use of seeded scaffolds in diabetic humans in whom a single scaffold seeded with multiple encapsulated islets can more readily be removed if needed for safety reasons than can multiple encapsulated islets not seeded into a scaffold. Full article

Takotsubo syndrome (TTS), popularly known as “broken heart syndrome”, is a type of reversible but not benign acute heart failure condition of unknown etiology, usually triggered by physical or emotional stress, affecting primarily elderly women. Recently a subtype of TTS, triggered by positive/pleasant emotions, has been identified (“happy heart syndrome”) with affected patients showing the same complications, including in-hospital and long-term mortality, as the patients afflicted with the “broken heart syndrome”. There is a need to increase the awareness of physicians, other medical providers, our patients, and the general public about the existence of “happy heart syndrome”. Full article

(1) Lifestyle changes to modify unhealthy dietary patterns with the goal of preventing MASLD have proven challenging. Here, dietary proteins and their modification with ammonium hydroxide enhancement (AHE) provide molecular evidence that this novel approach may attenuate the development of MASLD without undue dietary adjustments, potentially bypassing non-compliance. (2) High-fat diets containing dietary beef (HFB) or casein (HFC) + AHE (HFBN and HFCN, respectively) were fed to 256 C3H/HeJ female and male mice long term. At 6, 12, or 18 months, hepatic samples were analyzed with targeted metabolomics (glucose, lactate, alanine, glutamine, carnitine) and Western analysis (β-catenin, glutamine synthetase, CYP3A4). RNA sequencing was performed on samples collected at 18 months (n = 3; male HFC n = 2). (3) Metabolomics results showed that at 18 months, hepatic glutamine was greater in HFBN versus HFCN in females, whereas in males, hepatic glutamine, glucose and lactate were lower in HFBN versus HFCN. Additionally, diets with AHE decreased β-catenin and CYP3A4 protein expression in males. Ingenuity pathway analysis (IPA) of RNA-seq data predicted that HFBN activates PPARα signaling in the liver in both sexes compared to HFCN. Inflammatory activity showed predicted activation for females in the HFBN:HFCN comparison. In males, the inflammatory pathway molecular mechanisms of cancer was predicted as deactivated in HFBN:HFCN. (4) Dietary protein source impacts outcomes, and these outcomes improved with AHE. The HFBN diet improves signaling associated with lipid utilization for females and males, and improved inflammatory signaling for males compared with HFCN. Further exploration of AHE as a dietary intervention in high-fat diets is warranted. Full article

Dystocia represents a multifactorial and clinically significant reproductive disorder affecting a broad spectrum of reptilian species. Commonly resulting from prolonged vitellogenesis, endocrine disruption, or hepatic lipidosis, dystocia is often exacerbated by suboptimal husbandry or concurrent disease. This review critically evaluates the etiology, diagnostic criteria, and therapeutic interventions associated with this condition. Emphasis is placed on the interplay between metabolic exhaustion and hepatic compromise, which may lower the threshold for surgical intervention. The efficacy and limitations of oxytocin-based protocols are discussed in the context of hormonal receptor variability and response attenuation. Advanced diagnostic modalities, including ultrasonography, radiography/CT, and biochemical profiling, are reviewed for their utility in case stratification. Finally, surgical management options are considered for cases refractory to medical treatment, with attention paid to timing, anesthetic risk, and post-operative care. Collectively, this synthesis aims to inform evidence-based clinical decision-making and promote improved standards of care in reptile reproductive medicine. Full article

Reducing energy demand and carbon emissions in residential buildings requires more than technological upgrades; it demands a nuanced understanding of occupant behaviour. Residential energy use is shaped by both physical design and human actions, yet behavioural factors remain underexplored, contributing to the energy performance gap. This study addresses this issue by developing and validating a behavioural framework grounded in the Theory of Planned Behaviour (TPB) to examine how attitudes, social norms, perceived control, and environmental awareness influence energy-related decisions. Data were collected through an online survey of 310 households in metropolitan Sydney and analysed using Stata v17 software employing principal component analysis and regression modelling. Results reveal that environmental awareness is the most significant predictor of pro-environmental intention, which strongly correlates with actual behavioural outcomes. While attitudes and perceived control were generally positive, subjective norms and awareness remained moderate, limiting behavioural change. The proposed framework demonstrates strong validity and reliability, offering a practical tool for policymakers, designers, and educators to integrate behavioural insights into sustainable building strategies. By prioritising awareness campaigns and normative interventions, stakeholders can complement technical retrofits with behavioural measures, accelerating progress towards low-carbon housing and benefiting both households and the broader community. Full article

In today’s rapidly evolving business environment, digitalization has emerged not only as a technological trend but also as a strategic imperative. This paper develops a conceptual framework that examines how Industry 4.0 (I4.0) technologies and tools drive strategic innovation and enable the transformation of business models. Based on a systematic literature review, the framework identifies a set of organizational and contextual preconditions (strategic vision, organizational culture, digital skills, infrastructure, financial resources, and regulatory conditions) that can act as either enablers or barriers to innovation. The analysis reveals that these preconditions give rise to two contrasting innovation cycles: a virtuous cycle, where favourable conditions amplify the adoption of digital technologies and foster business model transformation, and a vicious cycle, where unfavourable conditions reinforce technological inertia and hinder strategic development. By integrating insights from innovation management, digital transformation, and business model theory, the framework offers a nuanced understanding of how technology and strategy intersect and provides actionable guidance for managers seeking to move beyond operational improvements toward reimagining value creation, delivery, and capture in the digital age. Full article

Construction of new seawater reverse osmosis desalination (SWRO) plants in the state of California (USA) requires environmental permits containing rather strict conditions. The California Ocean Plan requires the use of subsurface intake systems (SSIs) unless they are deemed to be not feasible. The Governor of California requested that the State Water Resources Control Board (State Board) study the issue of accelerating the desalination plant permitting process and making it more efficient. The State Board formed an independent scientific Panel to study the issue of SSI feasibility and to submit a report. The Panel recommendations included the following: the feasibility assessment (FA) for SSIs should be streamlined for completion within a maximum of three years, and this requirement should be added to the Ocean Plan; applicants need to perform a financial feasibility study before pursuing SSI capacities exceeding 38,000 m³/d (10 MGD) for wells or 100,000 m³/d (25 MGD) for galleries because project financing may be denied for such larger capacity systems; the mitigation options for each site–SSI combination in the screening process should be addressed by both the project proponent and regulatory agencies as early as practicable in the overall permitting process; and the impacts of SSIs on local aquifers and associated wetland systems must be assessed during the analyses conducted during the FA and during post-construction monitoring. The Panel further concluded that the design and evaluation of SSI–site combinations are highly site-specific, involving technically complex issues, which require both the applicant and the reviewing state agencies to have the expertise to design and review the applications. Economic feasibility must consider cost to the consumer and the engineering risk that can preclude project financing. Projected capacities exceeding the above noted limits may not by financed due to risks of failure or could require government guarantees to lenders. The current permitting system in California is likely to preclude construction of large seawater desalination facilities that can provide another source of potable water for coastal communities in California during severe droughts. Without seawater desalination, the potable water supply in California would suffer a greater sustainability and resilience risk during future periods of extended drought. Full article

Non-isocyanate polyurethanes (NIPUs) represent a sustainable alternative to conventional isocyanate-based systems, eliminating toxic reagents while maintaining good performance. In this study, bio-based NIPU coatings were synthesized from carbonated soybean oil (CSBO) via the carbonation of epoxidized soybean oil (ESBO) using carbon dioxide (CO₂), followed by polymerization with ethylenediamine (EDA) and varying concentrations of 3-aminopropyltriethoxysilane (APTES) (0–20 wt%). The amine groups of EDA and APTES participate in the ring-opening of cyclic carbonates to form β-hydroxyurethane linkages, while the triethoxysilane moieties of APTES may undergo hydrolysis–condensation to produce Si–O–Si domains, resulting in a β-hydroxyurethane–siloxane hybrid network. The optimized formulation CEA-5 exhibited the best, including a tensile strength of 3.3 MPa, elongation at break of ~150%, glass transition temperature (T_g) of ~7 °C, and thermal stability up to ~350 °C, where major thermal degradation happens. The synthesized coating material also shows adhesion (3.6 MPa on oak for CEA-10), hydrophobic behavior (water contact angle (WCA) ~102° for CEA-5), good chemical and ultraviolet (UV) resistance, and shape memory. The synergistic effect of urethane hydrogen bonding and siloxane crosslinking imparted enhanced toughness, flexibility, and durability. These findings express a scalable, eco-friendly strategy for producing silane-modified NIPU coatings with good mechanical, thermal, and coating performance suitable for sustainable industrial coating and adhesive applications. Full article

In recent years, photocatalysis using semiconductor materials has gained significant attention as an effective strategy for dye degradation under mild conditions. Among various metal oxide photocatalysts, zinc ferrite (ZnFe₂O₄) has gained attention due to its narrow band gap, good stability, low cost, and activation under visible light. ZnFe₂O₄ nanoparticles (NPs) were synthesized using a co-precipitation process and tested for their photocatalytic effectiveness in degrading synthetic dyes Fast Green FCF and Orange II Sodium Salt under visible light. This study emphasizes the benefits of utilizing ZnFe₂O₄ as a visible light-activated, cost-effective, and environmentally friendly photocatalyst. These findings add to the growing research on wastewater treatment options. Full article

Electric-field noise near ion-trap electrodes limits motional coherence and represents a key obstacle to scaling trapped-ion quantum systems. Here, we investigate how in situ Ar⁺ sputtering modifies motional heating and dephasing in multi-material surface-electrode traps. Trapped ions serve as local probes of electric-field fluctuations before and after controlled sputtering cycles. The data reveal a non-monotonic dependence of both the dephasing rate and the electric-field noise on the extent of Ar⁺ sputtering, with coherence initially improving while heating rates increase, followed by a reversal at longer exposures. This behavior highlights the intricate balance between beneficial surface cleaning and detrimental structural modification, driven by changes in surface morphology, redeposition of sputtered material, and diffusion on the surface, underscoring the complex interplay between surface composition and motional stability in multi-material electrode systems. Post-treatment scanning electron microscopy and energy-dispersive X-ray spectroscopy confirm significant modification of the multilayer structure. Technical noise was independently verified to be well below the observed levels. These findings indicate that in situ sputtering modifies surface properties in ways that can either mitigate or enhance electric-field noise, underscoring the need for precise control of material interfaces in next-generation ion-trap architectures. Full article