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2 Results Found

  • Article
  • Open Access
30 Pages
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A Hydrolase-Rich Venom Beyond Neurotoxins: Integrative Functional Proteomic and Immunoreactivity Analyses Reveal Novel Peptides in the Amazonian Scorpion Brotheas amazonicus

  • Gisele Adriano Wiezel,
  • Karla de Castro Figueiredo Bordon,
  • Jonas Gama Martins,
  • Viviane Imaculada do Carmo Custódio,
  • Alessandra Kimie Matsuno,
  • Rudi Emerson de Lima Procópio and
  • Eliane Candiani Arantes
Int. J. Mol. Sci.2026, 27(3), 1475;https://doi.org/10.3390/ijms27031475

2 February 2026

The scorpion family Buthidae, renowned for its neurotoxin-rich venoms, dominates toxinology, while non-buthid venoms remain largely unexplored. Here, we present a comprehensive proteomic and biochemical characterization of the Amazonian chactid scorp...

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  • Article
  • Open Access
2 Citations
2,285 Views
23 Pages
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Pioneering Comparative Proteomic and Enzymatic Profiling of Amazonian Scorpion Venoms Enables the Isolation of Their First α-Ktx, Metalloprotease, and Phospholipase A2

  • Karla C. F. Bordon,
  • Gabrielle C. Santos,
  • Jonas G. Martins,
  • Gisele A. Wiezel,
  • Fernanda G. Amorim,
  • Thomas Crasset,
  • Damien Redureau,
  • Loïc Quinton,
  • Rudi E. L. Procópio and
  • Eliane C. Arantes
Toxins2025, 17(8), 411;https://doi.org/10.3390/toxins17080411

15 August 2025

Scorpionism is a growing public health concern in Brazil, with the Amazon region presenting the highest mortality rates but remaining understudied, especially regarding local scorpion venoms composition. This study presents the first comprehensive bi...

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