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4 Results Found

  • Article
  • Open Access
15 Citations
3,331 Views
16 Pages

Amauroderma rugosum Extract Suppresses Inflammatory Responses in Tumor Necrosis Factor Alpha/Interferon Gamma-Induced HaCaT Keratinocytes

  • Polly Ho-Ting Shiu,
  • Jingjing Li,
  • Chengwen Zheng,
  • Panthakarn Rangsinth,
  • Renkai Li,
  • Queenie Tze-Lam Cheung,
  • Angel Heng-Yee Lau,
  • Jacqueline Cho-Ki Chan,
  • Yiu-Wa Kwan and
  • George Pak-Heng Leung
  • + 1 author

3 October 2022

Keratinocytes form the physical barrier of the skin and play an important role in the inflammatory process. Amauroderma rugosum is an edible mushroom; however, its pharmacological properties have seldom been studied. Although the anti-inflammatory ef...

  • Article
  • Open Access
6 Citations
3,876 Views
15 Pages

Neuroprotective Effects of Polysaccharides and Gallic Acid from Amauroderma rugosum against 6-OHDA-Induced Toxicity in SH-SY5Y Cells

  • Panthakarn Rangsinth,
  • Nattaporn Pattarachotanant,
  • Wen Wang,
  • Polly Ho-Ting Shiu,
  • Chengwen Zheng,
  • Renkai Li,
  • Tewin Tencomnao,
  • Siriporn Chuchawankul,
  • Anchalee Prasansuklab and
  • George Pak-Heng Leung
  • + 2 authors

22 February 2024

The pharmacological activity and medicinal significance of Amauroderma rugosum (AR) have rarely been documented. We examined the antioxidant and neuroprotective effects of AR on 6-hydroxydopamine (6-OHDA)-induced neurotoxicity in an SH-SY5Y human neu...

  • Review
  • Open Access
36 Citations
8,438 Views
40 Pages

Potentials of Natural Antioxidants in Reducing Inflammation and Oxidative Stress in Chronic Kidney Disease

  • On Ying Angela Lee,
  • Alex Ngai Nick Wong,
  • Ching Yan Ho,
  • Ka Wai Tse,
  • Angela Zaneta Chan,
  • George Pak-Heng Leung,
  • Yiu Wa Kwan and
  • Martin Ho Yin Yeung

Chronic kidney disease (CKD) presents a substantial global public health challenge, with high morbidity and mortality. CKD patients often experience dyslipidaemia and poor glycaemic control, further exacerbating inflammation and oxidative stress in t...

  • Article
  • Open Access
26 Citations
6,003 Views
21 Pages

21 December 2020

Phytase is an enzyme that breaks down phytates to release phosphorus in an available form. This enzyme plays an important role in animals, especially monogastric animals. It serves to improve phytate digestion along with phosphorus absorption, which...