Myeloid leukaemia (ML) is a cancer that occurs by the accumulation of abnormally multiplied myeloid cells in bone marrow, peripheral blood, and other related tissue. MST3 is a gene of the GCK family that has a role in apoptosis, along with other cell...
The mammalian STE 20-like protein kinase 4 (MST4) gene is highly expressed in several cancer types, but little is known about the role of MST4 in breast cancer, and the function of MST4 during epithelial-mesenchymal transition (EMT) has not been full...
In March 2024, UN Tourism (formerly UNWTO) released for publication the Statistical Framework for Measuring Sustainable Tourism (SF-MST). The SF-MST is claimed to give a full account of tourism’s current and future economic, social and environm...
K+ loading inhibits NKCC2 (Na-K-Cl cotransporter) and NCC (Na-Cl cotransporter) in the early distal tubules, resulting in Na+ delivery to the late distal convoluted tubules (DCTs). In the DCTs, Na+ entry through ENaC (epithelial Na channel) drives K+...
Sugars are critical for plant growth and development as suppliers of carbon and energy, as signal molecules, or as solute molecules for osmotic homeostasis. Monosaccharide transporter (MST) genes are involved in various processes of plant growth and...
The MST/Hippo signalling pathway was first described over a decade ago in Drosophila melanogaster and the core of the pathway is evolutionary conserved in mammals. The mammalian MST/Hippo pathway regulates organ size, cell proliferation and cell deat...
The absence of skin color information in skin cancer datasets poses a significant challenge for accurate diagnosis using artificial intelligence models, particularly for non-white populations. In this paper, based on the Monk Skin Tone (MST) scale, w...
The increasing frequency of global forest fires necessitates rapid and accurate detection methods. This study proposes a forest fire detection and segmentation framework based on the MST++ hyperspectral reconstruction model to improve the accuracy an...
Metabolic dysfunction-associated steatotic liver disease (MASLD) and its advanced subtype, metabolic dysfunction-associated steatohepatitis (MASH), have emerged as the most common chronic liver disease worldwide, yet there is no targeted pharmacother...
MST1R (RON) is a receptor of the MET tyrosine kinase receptor family involved in several cancers such as pancreas, breast, ovary, colon, and stomach. Some studies have shown that overexpression of MST1R increases the migratory and invasive properties...
The discrete activation of individual caspases is essential during T-cell development, activation, and apoptosis. Humans carrying nonfunctional caspase-8 and caspase-8 conditional knockout mice exhibit several defects in the progression of naive CD4+...
Based on long-term observations from Wuhan and Beijing MST (Mesosphere-Stratosphere-Troposphere) radars, we analyzed the climatological properties of mid-latitude mesospheric winds and evaluated them against the Horizontal Wind Model (HWM14). Measure...
Oxidative stress has been considered as the main mediator in neurodegenerative diseases. A high-fat diet (HFD) and metabolic diseases result in oxidative stress generation, leading to various neurodegenerative diseases via molecular mechanisms that r...
The monosaccharide transporter (MST) family mediates soluble sugar transport and distribution, playing critical roles in plant growth, development, and fruit sugar accumulation. Citrus is a globally important fruit crop whose organoleptic quality dep...
Atmospheric turbulence refers to the random and irregular airflow in the three-dimensional Earth’s atmosphere, and the atmospheric refractive index structure constant
During heavy rain on 1–2 June 2015 in central China, the Wuhan mesosphere–stratosphere–troposphere (MST) radar was applied to record the atmospheric responses to the rain with a 30 min period. According to the vertical gradient of t...
The fundamental attribute that is essential for the seismic capacity assessment of houses is the building structure type. Conventionally, remote sensing assessment of the seismic capacity for houses has been based on the image features of individual...
Diabetes mellitus (DM) is one of the major causes of death in the world. There are two types of DM—type 1 DM and type 2 DM. Type 1 DM can only be treated by insulin injection whereas type 2 DM is commonly treated using anti-hyperglycemic agents...
Metabolic remodeling is a critical skill of malignant cells, allowing their survival and spread. The metabolic dynamics and adaptation capacity of cancer cells allow them to escape from damaging stimuli, including breakage or cross-links in DNA stran...
Numerous studies have demonstrated that animal brains accurately infer whether multisensory stimuli are from a common source or separate sources. Previous work proposed that the multisensory neurons in the dorsal medial superior temporal area (MST-d)...
Background/Objectives: Lung cancer survival depends on early detection; however, in the Philippines, high radiologist workloads and the anatomical complexity of chest X-rays (CXRs) contribute to missed pulmonary nodules and false-negative diagnoses....
The optimal reconfiguration of electrical distribution feeders is a fundamental strategy for reducing active power losses and improving voltage profiles, yet it remains a challenging mixed-integer nonlinear programming (MINLP) problem due to the comb...
The MST1R/RON receptor tyrosine kinase is a homologue of the more well-known MET receptor. Like MET, RON orchestrates cell signaling pathways that promote oncogenesis and enable cancer cell survival; however, it has a more unique role in the regulati...
Background/Objectives: Currently, there is limited knowledge on the molecular mechanisms of the “non-canonical” Hippo signaling pathway in hematopoietic tumor cells. We have shown that targeting the MST1/2 kinases, which are the key molec...
Based on three years of data observed by Beijing MST radar between 2012 and 2014, this study gives the distribution characteristics of the turbulence energy dissipation rate ε and the vertical turbulence diffusion coefficient
To address the challenges in current research on spatial clustering algorithms for buildings in topographic maps—namely, their limited ability to effectively accommodate diverse application scenarios, including dense and regular urban environme...
Background: Kazakhstan’s railway network exhibits substantial spatial heterogeneity, limiting the effectiveness of uniform freight management strategies and necessitating differentiated analytical approaches to regional transport planning. This...
The performance of general circulation models (GCMs) in simulating horizontal winds is important because the distribution and variation in horizontal winds are central to investigating atmospheric dynamic characteristics and processes. Also, horizont...
Background/Objectives: Spermatogenesis is a key process in male reproduction that, if it does not happen correctly, can lead to infertility, with diabetes being one of the most prevalent causes of spermatogenesis disruption. Currently, there is a lac...
3-Mercaptopyruvate sulfurtransferase (MST) is one of the principal enzymes for the production of hydrogen sulfide and polysulfides in mammalians, and emerging evidence supports the physiological significance of MST. As a fundamental study of the phys...
Coxiella burnetii, the zoonotic agent of Q fever, has a worldwide distribution including Iran. However, no information regarding the circulating genotype of this infection has been reported in Iran. This study aimed to evaluate the genetic diversity...
Glioblastoma multiforme (GBM) and malignant gliomas are the most common primary malignant brain tumors. Temozolomide (TMZ) chemotherapy plus radiation therapy (RT), admi-mistered after debulking surgery, increased the median survival time (MST) from...
The Hippo pathway regulates a complex signalling network which mediates several biological functions including cell proliferation, organ size and apoptosis. Several scaffold proteins regulate the crosstalk of the members of the pathway with other sig...
This work presents the development of a wireless sensor system for environmental monitoring based on the modulated scattering technique (MST). The MST sensor probes are based on the scattering properties of small passive antennas and radiate part of...
Background and Objectives: Primary malignant bone tumors are rare lesions, and their complex treatment can lead to functional impairment. It is important to have a postoperative assessment tool for patients’ functional outcomes to be evaluated...
Due to its rich nutritional value, yak milk is an important food source in the alpine pastoral areas. However, yaks have a low milk yield. The Hippo pathway participates in cell proliferation and organ development. We aimed to determine the regulator...
An algorithm of pre-equilibrium clustering of spectator matter based on the construction of the minimum spanning tree (MST) is presented. The algorithm was implemented in the Abrasion-Ablation Monte Carlo for Colliders (AAMCC) model designed to study...
In Algeria, data on the epidemiology of coxiellosis in cattle are still lacking. In this study, bulk tank milk (BTM) samples from 200 randomly selected dairy cattle herds from Setif province of Algeria were analyzed by an indirect enzyme-linked immun...
Medical self-service terminals (MSTs) offer potential advantages for optimizing workflows and enhancing patient experience in hospitals, particularly for the elderly. Despite this, the uptake of MSTs among older adults in China remains a challenge. T...
Fecal contamination of water constitutes a serious health risk to humans and environmental ecosystems. This is mainly due to the fact that fecal material carries a variety of enteropathogens, which can enter and circulate in water bodies through feca...
The Murine Double Minute 2 (MDM2) amplification or overexpression has been found in many tumors with high metastatic and angiogenic ability. Our experiments were designed to explore the impact of MDM2 overexpression, specifically on the levels of ang...
Background: Assessments of functional capacity require considerable time and space and are thus generally not suitable for home-based assessments. Reproducibility measures from tests evaluating functional capacity suitable for home-based assessment a...
We are looking for tools to identify, model, and measure systemic risk in the insurance sector. To this aim, we investigated the possibilities of using the Dynamic Time Warping (DTW) algorithm in two ways. The first way of using DTW is to assess the...
3-mercaptopyruvate sulfurtransferase (3-MST) plays the important role of producing hydrogen sulfide. Conserved from bacteria to Mammalia, this enzyme is localized in mitochondria as well as the cytoplasm. 3-MST mediates the reaction of 3-mercaptopyru...
Background/Objectives: Hydrogen sulfide (H2S) is a vasorelaxant gas and exerts anti-oxidative, anti-inflammatory, and cytoprotective effects. H2S has been implicated in regulating placental vaso-activity and angiogenesis. It is believed that abnormal...
Background: The Hippo signaling pathway has a key role in tumorigenesis. This study aimed to evaluate the relationship between the expression of core components of the Hippo signaling pathway and its association with clinicopathological features in e...
The efficient industrial production of citric acid by A. niger requires overcoming the limitations of substrate uptake and citrate export on the citrate synthesis efficiency. This study addresses these obstacles using a transporter engineering strate...
Background/Objectives: Malnutrition is a common but underrecognized complication in colorectal cancer (CRC), contributing to poor treatment outcomes and reduced quality of life. Regional data from the Gulf remains limited. This study assessed the pre...
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor involved in xenobiotic metabolism, immune regulation, and cellular homeostasis. AhR-ligand interactions have traditionally been investigated using radioligand binding assa...
Background and Objectives: Inflammatory bowel disease (IBD), which includes Crohn’s disease (CD) and ulcerative colitis (UC), often necessitates long-term treatment and hospitalizations and also may require surgery. The macrophage-stimulating 1...
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