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Article

21 Citations

4,280 Views

22 Pages

Design of Polymeric Nanocapsules for Intranasal Vaccination against Mycobacterium Tuberculosis: Influence of the Polymeric Shell and Antigen Positioning

Lara Diego-González,
José Crecente-Campo,
Matthew John Paul,
Mahavir Singh,
Rajko Reljic,
María José Alonso,
África González-Fernández and
Rosana Simón-Vázquez

Pharmaceutics2020, 12(6), 489;https://doi.org/10.3390/pharmaceutics12060489

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28 May 2020

Tuberculosis (TB) is the leading cause of death from a single infectious microorganism and Bacillus Calmette Guerin (BCG), the only authorized vaccine, does not confer protection against pulmonary TB. Based on the hypothesis that mucosal protection c...

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Article

19 Citations

8,196 Views

15 Pages

Development of Gold-Nanoparticle-Based Lateral Flow Immunoassays for Rapid Detection of TB ESAT-6 and CFP-10

Palesa Pamela Seele,
Busiswa Dyan,
Amanda Skepu,
Charlotte Maserumule and
Nicole Remaliah Samantha Sibuyi

Biosensors2023, 13(3), 354;https://doi.org/10.3390/bios13030354

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6 March 2023

The current study reports on the development of a rapid and cost-effective TB-antigen diagnostic test for the detection of Mycobacterium biomarkers from non-sputum-based samples. Two gold nanoparticle (AuNP)-based rapid diagnostic tests (RDTs) in the...

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