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1,868,453 Results Found

  • Article
  • Open Access

A Distribution-Based Metric for Quantifying Dispersibility in Dry Powder Inhalers

  • Grace Xia,
  • Bhanuz Dechayont,
  • Linze Che,
  • Isabel Comfort and
  • Ashlee D. Brunaugh
Pharmaceutics2026, 18(3), 283;https://doi.org/10.3390/pharmaceutics18030283 
(registering DOI)

24 February 2026

Background/Objectives: Reproducible evaluation of aerosol dispersibility remains a key challenge in the development of dry powder inhalers (DPIs), where small variations in particle cohesion, morphology, or device resistance can lead to large differe...

  • Article
  • Open Access
Logistics2026, 10(3), 52;https://doi.org/10.3390/logistics10030052 
(registering DOI)

24 February 2026

Background: Amid global sustainability imperatives, the logistics sector serves as a key economic enabler while remaining a major contributor to greenhouse gas emissions. This study investigates the causal relationships between green logistics practi...

  • Review
  • Open Access
Biology2026, 15(5), 373;https://doi.org/10.3390/biology15050373 
(registering DOI)

24 February 2026

Oral squamous cell carcinoma (OSCC) is a highly aggressive malignancy characterized by frequent recurrence and metastasis, which poses a significant global health problem. One of the prominent hallmarks of cancer is glucose metabolic reprogramming, w...

  • Article
  • Open Access

Experiment Tests and Numerical Simulations of Leakage from Double-Hull Oil Tanks in a Fixed State

  • Wenzhuo Zhang,
  • Renqing Zhu,
  • Xinlong Zhang,
  • Qingyi Qu and
  • Hui Zhao
J. Mar. Sci. Eng.2026, 14(5), 412;https://doi.org/10.3390/jmse14050412 
(registering DOI)

24 February 2026

To investigate the leakage characteristics of damaged double-hull oil tanks in still water, this study conducted both model tests and numerical simulations on the leakage process of a damaged double-hull oil tank model. Based on a 75,000 DWT oil tank...

  • Article
  • Open Access

Access Control Development Within the Framework of an IOTA-Based Electronic Medical Record Management System

  • Hari Purnama,
  • I Putu Bakta Hari Sudewa,
  • Tazkia Nizami,
  • Bagas Sambega Rosyada,
  • Pradipta Rafa Mahesa and
  • Nur Ahmadi
Sensors2026, 26(5), 1422;https://doi.org/10.3390/s26051422 
(registering DOI)

24 February 2026

Electronic Medical Records (EMRs) are mandatory in Indonesia following the Ministry of Health regulation, which raises significant challenges in data security and patient-centric access control. Current implementations rely on centralized healthcare...

  • Article
  • Open Access

GsEXPA8 Improves Alkaline Tolerance in Lupinus angustifolius by Modulating Root Architecture, Stress-Responsive Gene Expression, and Rhizosphere Microbiome

  • Mengyu Liu,
  • Yujing Liu,
  • Hongli Wang,
  • Yijia Ruan,
  • Xiaoyu Wang,
  • Xinlei Du,
  • Mengyu Zhou,
  • Yishan Fu,
  • Jixiang Tang and
  • Lei Cao
  • + 1 author
Plants2026, 15(5), 679;https://doi.org/10.3390/plants15050679 
(registering DOI)

24 February 2026

Lupinus angustifolius is an important leguminous ornamental species, but its productivity is often compromised by alkaline soil stress. GsEXPA8, an expansin gene identified in wild soybean (Glycine soja), has been implicated in alkali stress toleranc...

  • Article
  • Open Access

Assessing the Relationship Between Erosion Risk, Climate Change and Archaeological Heritage: Medieval Sites in the Basilicata Region, Italy

  • Alessia Frisetti,
  • Nicodemo Abate,
  • Antonio Minervino Amodio,
  • Dario Gioia,
  • Giuseppe Corrado,
  • Maria Danese,
  • Gabriele Ciccone and
  • Nicola Masini
Heritage2026, 9(3), 89;https://doi.org/10.3390/heritage9030089 
(registering DOI)

24 February 2026

Climate change has among its effects the increasing frequency and intensity of natural disasters, such as landslides, floods, erosion and fires, with clear implications on both natural and anthropic hazards and risks. These natural phenomenapose a gr...

  • Article
  • Open Access

Depression Detection from Three-Channel Resting-State EEG Using a Hybrid Conv1D and Spectral–Statistical Fusion Model

  • Oana-Isabela Știrbu,
  • Florin-Ciprian Argatu,
  • Felix-Constantin Adochiei,
  • Bogdan-Adrian Enache and
  • George-Călin Serițan
Sensors2026, 26(5), 1417;https://doi.org/10.3390/s26051417 
(registering DOI)

24 February 2026

Major depressive disorder requires scalable, low-burden screening tools. We examined whether three-channel resting-state EEG can support reliable discrimination between major depressive disorder and healthy controls using a lightweight model compatib...

  • Article
  • Open Access

Effect of Post-Build Annealing on the Microstructure and Mechanical Properties of LPBF-Processed AlSn10Pb10 Alloy

  • Kirill O. Akimov,
  • Alexander L. Skorentsev,
  • Nikolay M. Rusin,
  • Vadim E. Likharev,
  • Dmitry P. Ilyashchenko and
  • Andrey I. Dmitriev

The work studied the effect of high-temperature annealing on the phase composition, microstructure, and mechanical properties of an AlSn10Pb10 vol.% alloy obtained by laser powder bed fusion (LPBF). For this purpose, a series of anneals was carried o...

  • Article
  • Open Access

24 February 2026

Mitochondria–endoplasmic reticulum contacts (MERCs) are physical structures formed between mitochondria and the endoplasmic reticulum (ER) through various tethering proteins, playing crucial roles in multiple physiological processes, including...

  • Article
  • Open Access

24 February 2026

Turbine blades serve as critical components in aircraft engines, yet casting defects inevitably arise during manufacturing. Therefore, accurate pre-service turbine blade defect detection is critical for aircraft engine safety. However, existing deep...

  • Article
  • Open Access

Graph Convolution Neural Network and Deep Q-Network Optimization-Based Intrusion Detection with Explainability Analysis

  • Kelvin Mwiga,
  • Mussa Dida,
  • Leandros Maglaras,
  • Ahmad Mohsin,
  • Helge Janicke and
  • Iqbal H. Sarker

24 February 2026

As networks expand in size and complexity, coupled with an exponential increase in intrusions on network and IoT systems, this leads to traditional models failing to capture increasingly intricate correlations among network components accurately. Gra...

  • Article
  • Open Access

Assessing Flood Susceptibility Using a Data-Driven, GIS-Based Frequency Ratio Model

  • Roshan Sewa,
  • Bishal Poudel,
  • Sujan Shrestha,
  • Dewasis Dahal and
  • Ajay Kalra

24 February 2026

Flooding is one of the major natural disasters that have a major impact on urban areas due to the increasing intensity of factors like extreme weather conditions, climate change, and unplanned urbanization. Considering Cook County, Illinois, the rapi...

  • Article
  • Open Access

24 February 2026

The accelerating transition toward carbon neutrality necessitates the synergistic integration of power and hydrogen systems to mitigate renewable intermittency; however, coordinating regulatory policies with the operational flexibility of these coupl...

  • Communication
  • Open Access

Impedimetric Detection of Free Fatty Acids in Patient Serum Using Commercially Available Screen-Printed Carbon Electrode

  • İsmail Oran,
  • Halil İbrahim Özdemir,
  • Turgay Yılmaz Kılıç,
  • Hilmiye Deniz Ertuğrul Uygun,
  • Hakan Gökalp Uzun,
  • Barış Kılıçaslan,
  • Evrim Şimşek,
  • Yusuf Ali Altuncı,
  • Şadiye Mıdık and
  • Ali Murat Ergin

Objective: The performance of chrono-impedance measurement, a novel electrochemical method for determining free fatty acids (FA), was evaluated in a real-world clinical setting. Methods: Patients presenting to the emergency department with chest pain...

  • Review
  • Open Access

24 February 2026

Confronted with the severe imperatives to food security posed by a growing population and the urgent need for sustainable development amid climate change, traditional agricultural models face significant resource-intensive efficiency bottlenecks. Dee...

  • Article
  • Open Access

Safety of an SV-1 Cell Line-Based Varicella Vaccine Before and After Integration into the Expanded Program on Immunization: A Real-World Study in Jiangsu Province, China

  • Jing Yu,
  • Yurong Li,
  • Zhiguo Wang,
  • Xiang Sun,
  • Guodong Kang,
  • Borong Xu,
  • Yuanyuan Zhu,
  • Xun Li,
  • Xiaozhe Song and
  • Ran Hu
  • + 4 authors

24 February 2026

Background/Objectives: Varicella is a highly contagious childhood disease that may cause severe complications in susceptible populations. The SV-1 cell line-based varicella vaccine (VarV [SV-1]) has been increasingly used in routine immunization; how...

  • Article
  • Open Access

Annual Load Scenario Generation Using a Hybrid STL and Improved DDPM Approach

  • Heran Kang,
  • Hongyang Liu,
  • Jianfei Liu,
  • Ruichen Hao,
  • Xiang Wang,
  • Wenbo Hu,
  • Jie Chen,
  • Wei Yue,
  • Haibo Li and
  • Zongxiang Lu

24 February 2026

To address the limitations of existing annual load scenario generation methods, including insufficient ability to represent long-term trends, excessive randomness in generated scenarios, and inadequate consideration of special holiday conditions, in...

  • Article
  • Open Access

Architectural and Operational Drivers of Bedside Light Exposure Across Neonatal, Paediatric, and Adult Intensive Care Units: A Multicentre Real-World Study

  • Gizem Izmir Tunahan,
  • Feyza Inceköy Girgin,
  • Dincer Yildizdas,
  • Merih Cetinkaya,
  • Seyma Kilic and
  • Soyhan Bagci

24 February 2026

Light is a critical regulator of circadian physiology, yet its delivery in intensive care units (ICUs) is primarily determined by architectural features and clinical workflows rather than by biological timing. This multicentre study (34 ICUs across n...

  • Article
  • Open Access

An Adaptive PID Control Strategy Based on Offline–Online Cooperative Optimization

  • Jichi Yan,
  • Jizhen Li,
  • Mingfan Chen,
  • Huijia Zhou and
  • Yannan Yu

24 February 2026

To address the difficulty of simultaneously achieving fast response, high stability, and strong disturbance rejection in gimbal systems operating under complex conditions, an adaptive control strategy based on offline–online cooperative optimiz...

  • Review
  • Open Access

Review of Risk Factors Opioid Misuse and Addiction Following Traumatic Injury

  • Nicholas J. Lawler,
  • Bipasha Sobhani,
  • Ejura Yetunde Salihu,
  • Hannah Muller,
  • Jordan Edwards,
  • Megan Ringo and
  • Randall Brown

24 February 2026

Traumatic injuries represent a significant public health challenge, affecting millions worldwide annually and necessitating acute pain management that frequently involves the use of opioid analgesics to mitigate discomfort and facilitate recovery. Al...

  • Article
  • Open Access

24 February 2026

Background/Objectives: Evidence-based practice (EBP) is a core competence in physiotherapy, yet its implementation in routine clinical practice remains inconsistent. This study aimed to describe self-reported EBP competencies among physiotherapists a...

  • Article
  • Open Access

Parboiling improves rice-milling performance and consumer acceptance; however, drying parboiled rice can be energy intensive and highly sensitive to drying conditions, making it costly for processors. High head rice yield (HRY) and whiteness index (W...

  • Article
  • Open Access

SFWA-TweetyNet: Cross-Regional Acoustic Analysis of Red-Winged Blackbird Vocalizations via Automated Syllable Annotation

  • Zhicheng Zhu,
  • Ziqian Wang,
  • Danju Lv,
  • Yan Zhang,
  • Yueyun Yu,
  • Ting Zhou and
  • Haifeng Xu

24 February 2026

The syllable is the most fundamental acoustic unit in bird vocalizations and is highly informative of species-specific behavioral characteristics. However, because syllables vary significantly across different species and environments, existing sylla...

  • Article
  • Open Access

24 February 2026

Carbide lime (CL) and powdered glass (PG), as industrial by-products, possess significant potential as eco-friendly soil amendment materials. This paper presents a systematic investigation into the effectiveness and reaction mechanisms of a composite...

  • Article
  • Open Access

Structural, Dielectric, and Impedance Properties of Sintered Al6Si2O13 Composite for Electronic Applications

  • Nassima Riouchi,
  • Oussama Riouchi,
  • Abderrahmane Elmelouky,
  • Mohammed Mansori,
  • Boštjan Genorio,
  • Petranka Petrova,
  • Soufian El Barkany,
  • Mohamed Abou-Salama and
  • Mohamed Loutou

24 February 2026

Mullite (Al6Si2O13), an aluminosilicate with remarkable thermal and dielectric properties, is a promising material for advanced electronic applications. This study focuses on a sintered mullite composite and examines its structural, morphological, di...

  • Article
  • Open Access

24 February 2026

Basalt fiber-reinforced concrete is increasingly being used in shotcrete support systems for rock mass excavation engineering due to its superior mechanical properties and durability. Rapid freeze–thaw cycling tests were performed to simulate f...

  • Article
  • Open Access

Childhood anxiety is a significant mental health concern in India. Although the Revised Children’s Manifest Anxiety Scale-Second Edition (RCMAS-2) is widely used internationally, its psychometric performance in Indian populations is underexplor...

  • Article
  • Open Access

Meanings and Practices of Swaddling (qillpu) in Infant Care in Andean Communities

  • Edgar Gutiérrez-Gómez,
  • Roxana Rojas-Montes,
  • Sonia Beatriz Munaris-Parco,
  • Roly Auccatoma-Tinco,
  • Adolfo Quispe-Arroyo and
  • Rubén Darío Alania-Contreras

24 February 2026

Swaddling, known in Quechua as qillpu, is an ancestral practice still in use in Andean communities, linked to cultural conceptions of health, protection, and appropriate ways of raising babies. The objective of the research was to analyze the sociocu...

  • Article
  • Open Access

Metal-Decorated C8 Quantum Dots as Lightweight Hydrogen Storage Materials: A Comprehensive DFT Study

  • Seyfeddine Rahali,
  • Ridha Ben Said,
  • Youghourta Belhocine,
  • Suzan Makawi and
  • Bakheit Mustafa

24 February 2026

Lightweight, efficient, and reversible hydrogen storage materials are critical for the advancement of hydrogen-based energy technologies. In this work, we present a comprehensive density functional theory (DFT) investigation of hydrogen storage in pr...

  • Article
  • Open Access

24 February 2026

Series arc faults often occur in aging or faulty electrical systems due to insulation degradation, poor contact, or corrosion. These faults typically generate low current signatures, which are difficult to detect with traditional overcurrent protecti...

  • Article
  • Open Access

Study on the Different Thermal Insulation Methods to Control the Wellbore Temperature in Deepwater Wells

  • Bo Zhang,
  • Bowen Yu,
  • Jipei Sun,
  • Qing Wang,
  • Wei Fan,
  • Nu Lu,
  • Mengzhe Cai and
  • Tengfei Sun

24 February 2026

Thermal insulation is necessary for deepwater wells to achieve safe and effective production. Based on the comparison of different thermal insulation measures and the control requirements, this paper proposes two indicators to analyze thermal insulat...

  • Review
  • Open Access

24 February 2026

Reactive oxygen species (ROS) are widely recognized as intracellular signaling mediators and contributors to oxidative damage. Increasing evidence indicates that redox processes in the extracellular space constitute a distinct and functionally releva...

  • Article
  • Open Access

FireVision: An Early Fire and Smoke Detection Platform Utilizing Mask R-CNN Deep Learning Inferences

  • Konstantina Spanoudaki,
  • Meropi Tsoumani,
  • Sotirios Kontogiannis,
  • Myrto Konstantinidou,
  • Ion Anastasios Karolos and
  • George Kokkonis

24 February 2026

This paper presents FireVision, an innovative platform and model for real-time fire detection and monitoring. The platform utilizes automated drone flights to collect high-resolution imagery in both suburban and forested settings. Ensemble deep learn...

  • Article
  • Open Access

Post-COVID-19 Rabies Surveillance and Risk Factors in Rural Eastern Cape, South Africa: A One Health Perspective

  • Sithabile Moso,
  • Laston Gonah,
  • Mojisola Clara Hosu,
  • Ntandazo Dlatu,
  • Teke Apalata and
  • Lindiwe Modest Faye

24 February 2026

Background: Rabies remains a neglected zoonotic disease in South Africa, particularly in rural areas where surveillance weaknesses, behavioral gaps, and limited One Health coordination persist. Objectives: This study assessed rabies surveillance, beh...

  • Review
  • Open Access

24 February 2026

Urban transport systems are major contributors to air pollution in rapidly growing post-Soviet metropolitan areas. Almaty, Kazakhstan’s largest city, has experienced a sharp rise in private vehicle ownership, accompanied by persistent exceedanc...

  • Article
  • Open Access

24 February 2026

Rain, snow, fog, and dust can degrade road-scene images, blur fine details, and consequently reduce the reliability of perception systems for autonomous driving. To address this problem, this paper proposes PF-ConvNeXt, an adverse weather recognition...

  • Article
  • Open Access

24 February 2026

The development of new energy technologies is crucial for the future competitiveness of the automotive industry. Green innovation is a key driver of industrial transformation and advancement. Companies in the new energy vehicle (NEV) sector play a cr...

  • Article
  • Open Access

Camelid-Derived Nanobodies Targeting Human Epidermal Growth Factor Receptor: Screening, Expression, and Functional Validation

  • Yunfeng Liu,
  • Qiting Huang,
  • Dongna Zhang,
  • Yingjun Wang,
  • Shuaiying Zhao,
  • Jianchuan Wen,
  • Yingying Kong and
  • Jianfeng Xu

24 February 2026

Objectives: The epidermal growth factor receptor (EGFR) is a clinically relevant membrane receptor that is frequently overexpressed or dysregulated in multiple types of cancer, making it an important target for antibody-based strategies. Nanobodies,...

  • Article
  • Open Access

Fgf10 Gene Dosage from a Single Allele Is Insufficient for Forming Multilayered Epithelial Cells in the Murine Lacrimal Gland

  • Shiori Ikeda,
  • Keita Sato,
  • Yuki Tajika,
  • Hirofumi Fujita,
  • Tetsuya Bando,
  • Tsutomu Nohno,
  • Satoru Miyaishi and
  • Hideyo Ohuchi
Int. J. Mol. Sci.2026, 27(5), 2113;https://doi.org/10.3390/ijms27052113 
(registering DOI)

24 February 2026

Mutations in the fibroblast growth factor 10 (FGF10) gene in humans cause aplasia of the lacrimal and salivary glands (ALSG). In patients with ALSG, heterozygous loss-of-function mutations are found, and FGF10 haploinsufficiency results in the absenc...

  • Review
  • Open Access

Reading the Signature of Autophagy in the Ischemic and Infarcted Heart: A Systematic Review of Circulating Biomarkers

  • Davide Radaelli,
  • Asma Alshaeb,
  • Ibrahim Al-Habash,
  • Viktorija Belakaposka Srpanova,
  • Zlatko Jakovski,
  • Gianfranco Sinagra,
  • Anita Galic Mihic and
  • Stefano D’Errico

24 February 2026

Ischemic heart disease is the main cause of death worldwide. Classic cardiac biomarkers, such as troponin, which are released due to myocyte necrosis, are widely used for diagnosis, but they provide limited information about the initial underlying ce...

  • Article
  • Open Access

24 February 2026

Precision irrigation is crucial for sustainable agriculture, yet conventional single-objective optimization methods struggle to balance conflicting demands such as crop yield, operational cost, and environmental sustainability. This study introduces...

  • Article
  • Open Access

A Beam-Splitter-Free Terahertz Receiver with Independent Antenna-Fed Local Oscillator for Enhanced Efficiency

  • Pengfei Zhao,
  • Dabao Wang,
  • Xinyu Yao,
  • Ning Liu,
  • Xiaochun Jiao and
  • Jing Cao

24 February 2026

This paper presents the design, fabrication, and experimental characterization of a novel terahertz receiver comprising two high-performance receiving antennas and a combiner. The low efficiency of local oscillator (LO) power utilization, caused by c...

  • Article
  • Open Access

Liver and Skeletal Muscle Metabolome Characterization in Peripartal Dairy Cows Fed Rumen-Protected Methionine or Rumen-Protected Choline

  • Valentino Palombo,
  • Zheng Zhou,
  • Lam Phuoc Thanh,
  • Mariasilvia D’Andrea,
  • Daniel N. Luchini and
  • Juan J. Loor

24 February 2026

The transition period in dairy cows involves profound metabolic adaptations that challenge energy balance and liver function. This study evaluated the effects of rumen-protected methionine (RPM) and choline (RPC) on hepatic and skeletal muscle metabo...

  • Article
  • Open Access

Prevalence of Otitis Externa in a Population of Owned Cats in Northern Italy

  • Roberta Perego,
  • Eva Spada,
  • Claudia Avizzano,
  • Luciana Baggiani and
  • Daniela Proverbio

24 February 2026

Background: Although increasingly studied feline otitis externa (OE) prevalence is not yet well defined. The aim of this study was to assess the prevalence of OE in a population of privately owned cats in Northern Italy. Methods: Cats were clinically...

  • Systematic Review
  • Open Access

Informing the Development of Tailored Antenatal Care Services for Pregnant Adolescents: A Systematic Review and Stakeholder Survey

  • Karissa Bjornstad,
  • Emily Dawson,
  • Amir Ali Barket Ali Samnani,
  • Marko Kerac,
  • Amanda Murungi,
  • Stephanie V. V. Wrottesley and
  • Natasha Lelijveld

24 February 2026

Background: Pregnant adolescents are at higher risk of adverse birth outcomes. Tailoring antenatal care (ANC) to adolescents’ unique needs may be a way to reduce adverse maternal and child outcomes within this population. This systematic review...

  • Article
  • Open Access

Evolution of the Real Estate Market in Portugal in the 21st Century: An Analysis of the First Twenty-Five Years

  • Fernando Oliveira Tavares,
  • Luís Pacheco,
  • Margarita Carvalho and
  • Elisabeth T. Pereira

24 February 2026

This paper examines the evolution of the Portuguese residential real estate market during the first twenty-five years of the 21st century, focusing on the short-run determinants of housing transaction values. Using quarterly data from 2000 to 2025, t...

  • Review
  • Open Access

Hepatitis D Virus Pathogenesis: A Sense of Complications

  • Yann Haennel,
  • Thomas F. Baumert and
  • Joachim Lupberger

24 February 2026

Hepatitis D virus (HDV) is a satellite RNA virus of the hepatitis B virus (HBV) infecting an estimated 12 million people worldwide. Chronic HDV infection is causing the most severe form of chronic viral hepatitis, leading to a rapid progression of ch...

  • Review
  • Open Access

Roles of DNA Damage Response Pathway in the Regulation of the Nuclear Envelope

  • Yasunao Kamikawa,
  • Zuqian Wu,
  • Kenshiro Fujise,
  • Kazunori Imaizumi and
  • Atsushi Saito

The nuclear envelope (NE) functions as a barrier between the cytoplasm and nucleus. Over the past decade, NE has revealed unexpectedly divergent structural alterations. NE rupture triggers the uncontrollable exchange of macromolecules across the NE a...

  • Article
  • Open Access

Multi-Species Microbial Inoculants Enhance Turfgrass Quality, Nutrient Uptake, and Stress Resilience Under Temperate Polish Conditions

  • Adam Radkowski,
  • Magdalena Szpytma,
  • Monika Sitarek-Andrzejczyk,
  • Iwona Radkowska and
  • Henryk Bujak

24 February 2026

Sustainable care of urban lawns requires methods that maintain high turf quality while reducing the use of chemical fertilizers. The objective of this three-year field study was to evaluate whether microbial inoculants can complement or partially sub...

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