Special Issue "Analytical Separation Techniques Coupled to Mass Spectrometry for Detection of Some Chemicals and Their Metabolites in Water"

A special issue of Water (ISSN 2073-4441). This special issue belongs to the section "Aquatic Systems—Quality and Contamination".

Deadline for manuscript submissions: 8 July 2021.

Special Issue Editors

Prof. Dr. Giuliana Bianco
Guest Editor
Dipartimento di Scienze, Università degli Studi della Basilicata, Potenza, Italy
Interests: HRMS; LC-MS; GC-MS; CE-MS; metabolomics; environmental molecular; food science; clinical; functional; nutraceutical substances and cultural heritage safeguard
Prof. Dr. Laura Scrano
Guest Editor
Dipartimento delle Culture Europee e del Mediterraneo, Università degli Studi della Basilicata, Potenza, Italy
Interests: pharmaceuticals from plants and microorganisms; chemistry of natural substances in vegetables and soil; plant secondary metabolites; mass spectrometry
Special Issues and Collections in MDPI journals
Dr. Raffaella Pascale
Guest Editor
Environmental chemist-Consultant/Scientist, Via Giovanni XXIII, 120 Potenza, Basilicata, Italy
Interests: analysis of contaminants and their metabolites in different food and environmental matrices; validation of the methods, according to EPA, ICH, ISO, APAT, and EUROCHEM guidelines

Special Issue Information

Dear Colleagues,

Analytical protocols for the analysis of chemicals and their metabolites in water matrices continue to be an active research area closely related to environmental quality and safety. Environmental water contaminants of recent concern are pharmaceuticals, estrogens, and other endocrine-disrupting chemicals. In addition, pesticides, microorganisms, and humic substances (HS), in their function as vehicles for contaminants and as precursors for byproducts in water treatment, traditionally play an important role. In this field, mass spectrometry (MS) and its combination with chromatographic techniques has proved to be highly successful in gaining reliable data about the presence and abundance of contaminants and their metabolites in water matrices. This Special Issue in Water is devoted to manuscripts (research, reviews, short communications) describing methods for qualitative and quantitative analysis of chemicals in all types of environmental water bodies over time and space using mass spectrometry (MS) and tandem MS (MS/MS). We also anticipate an emphasis on the present status of the application of hyphenated techniques (LC-MS, GC-MS, etc.) for the determination of water contaminants, especially transformation products.

Prof. Dr. Giuliana Bianco
Prof. Dr. Laura Scrano
Dr. Raffaella Pascale
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Water is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • POPs
  • Drugs
  • Pharmaceuticals
  • LC-MS, GC-MS
  • Mass spectrometry
  • Tandem MS, HRMS, water analysis methods
  • Monitoring
  • Environment
  • Wastewater
  • Contamination
  • Validation

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:


Open AccessArticle
Determination of Volatile Fuel Oxygenates in Water by Gas Chromatography–Triple Quadrupole Mass Spectrometry: Effect of Automated Sample Preparation Techniques
Water 2020, 12(8), 2266; https://doi.org/10.3390/w12082266 - 12 Aug 2020
Considering the adverse effects of gasoline additives and aromatic compounds on the quality of the water supply and the ecological environment of the water, a methodology, with short chromatographic separation time (22.5 min) and high separation quality, was optimized for the determination of [...] Read more.
Considering the adverse effects of gasoline additives and aromatic compounds on the quality of the water supply and the ecological environment of the water, a methodology, with short chromatographic separation time (22.5 min) and high separation quality, was optimized for the determination of 11 common gasoline additives and aromatic compounds using gas chromatograph coupled with triple quadrupole mass spectrometer (GC–QqQ–MS/MS) system. The extraction procedure of analytes was performed by headspace solid–phase microextraction (HS–SPME) and purge and trap (P&T), respectively. Both of the two extraction methods provided excellent chromatographic resolution in subsequently GC–QqQ–MS/MS detection system, with the coefficients of linear regression of the calibration curves with HS–SPME and P&T pretreatments were 0.9965~0.9998 and 0.9961~0.9999, respectively, n = 7. The limit of detections (LODs) of these selected oxygenate compounds were discovered to be 0.52~32 ng/L in the P&T–GC–QqQ–MS/MS detection system and 0.11~151 ng/L in the HS–SPME–GC–QqQ–MS/MS detection system. For benzene, toluene, ethylbenzene and xylene isomers (BTEX), the HS–SPME–GC–QqQ–MS/MS system provided outstanding detection performance because of the lower LOD obtained. However, for other selected compounds, the P&T–GC–QqQ–MS/MS system offered lower LODs. The proposed extraction–detection procedure is a simple and sensitive analytical approach for the detection of gasoline additives and aromatic compounds in water. Full article
Show Figures

Figure 1

Back to TopTop