Special Issue "Chikungunya Virus and Emerging Alphaviruses"
Deadline for manuscript submissions: closed (1 August 2023) | Viewed by 26519
Interests: positive-strand RNA Zika virus; Chikungunya; Dengue virus; pathogenesis
Interests: virus genomes; dengue virus; SARS-COV-2; Zika virus; Mayaro virus; vaccine development; molecular diagnosis; bacteriophages; heterologous protein expression
Chikungunya virus (CHIKV) is a re-emerging arthropod-borne virus that is widespread in tropical regions. This virus belongs to the Alphavirus genus and is transmitted to humans by the bite of Aedes spp.-infected mosquitoes, a vector commonly found in many large cities. CHIKV has an immense impact on global public health, especially in middle- and low-income countries, in which access to health is limited. Chikungunya infection is usually characterized by an abrupt onset of fever, which is commonly followed by significant joint pain. Chikungunya virus-induced joint pain is often a very debilitating symptom, lasting from a few days to several weeks or even months. Other symptoms, such as atypical neurological manifestations, have also been reported; these include meningo-encephalitis, meningoencephalo-myeloradiculitis, myeloradiculitis, myelitis, myeloneuropathy, and Guillain–Barré syndrome. Besides CHIKV, other important Alphaviruses (Mayaro, Ross River, and Venezuelan equine encephalitis, among others) can cause human disease. Despite its importance, at the present no treatment or vaccines are available to control Alphavirus infections.
Although there have been significant advances in science—such as, for instance, the implementation of novel mRNA vaccines—new emerging and re-emerging viruses still represent a major challenge to the field. For this Special Issue, we welcome the submission of original research articles, review articles, and short communications that contribute to an improved understanding of Alphaviruses. Topics of interest include, but are not limited to:
- Alphaviruses epidemiology and virus surveillance (emergence and virus evolution);
- Advances in diagnostics, treatment, and vaccines;
- Basic virology molecular aspects;
- Alphaviruses pathogenesis (including, but not limited to, host response and host factors affecting infection outcomes, animal models of infection, host innate and adaptive immunity, virus immune response evasion);
- Measures for control and prevention.
Dr. Rafael Freitas de Oliveira Franca
Dr. Sergio de Paula
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- chikungunya virus
- innate immune response
- adaptive immune response
- animal model
- viral evolution
- in vitro
- in vivo
- mayaro virus
- ross river virus
- semliki forest virus
- venezuelan equine encephalitis virus