Special Issue "Bacteriophage Genomes and Genomics: News from the Wild"
Deadline for manuscript submissions: closed (30 November 2018).
Interests: molecular aspects of phage evolution: genome organization and rearrangements, mosaicism in temperate phage, phage recombination and mutagenesis; phage genome evolution in various ecological niches like the murine gastro-intestinal tract; emerging methods for phage genome annotation and analysis
In the jungle of the phage world, genomes analyses have started to bring some order: Genomics becomes a reliable tool to classify phages, and ICTV has recently begun implementing taxonomic classifications, based primarily on genomic data. The raising interest in phage therapy has launched phage discoveries for a variety of bacterial species, allowing to reduce the over-representation of model phage-like coliphages in databases, and to reach a more equilibrated view on the phage world. Teaching on its side has opened an unprecedented view on mycophages, and new teaching projects now tackle other genera, such as Bacilli or Streptomycetes. Finally, (meta)viromics and single whole genome amplification are also bringing to the shore a wealth of new genomes. As such, the time is ready to collect the most striking features of the recent discoveries into a single issue.
This wealth of data has also led to forge new tools dedicated to phage genome analyses, so that bio-informatics oriented manuscripts are also welcome in the special issue. Important questions are raised by some of the tools developed for virome analysis, such as the relevance of virome assemblies, the phage host or life style prediction issues. Benchmarking papers, or critical analyses on the state-of-the-art in this field will also be considered for publication in this Special Issue.
Dr. Marie-Agnès Petit
Manuscript Submission Information
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- phage genomics
- prediction tools