Rhinovirus Infections 2.0

Dear Colleagues,

Rhinoviruses are small nonenveloped RNA viruses belonging to the family Picornaviridae, and are recognized as the major cause of common colds and acute exacerbations of asthma and chronic obstructive pulmonary disorder (COPD) in humans. These viruses are extremely antigenically diverse in structure, with approximately 160 distinct serotypes/strains grouped into three types, A, B, and C, with further distinctions based on entry receptor requirements where three different cell-surface molecules have been described. Immunity to rhinoviruses is generally considered to be serotype-specific. Despite intensive studies since their discovery in the 1960s, no effective antiviral or vaccine has been invented to combat these ubiquitous pathogens. Thus, humans can expect to have three to five infections per year, and significantly more in children.

In this updated Special Issue of Viruses, we aim to gather research and review papers that contribute to an improved understanding of rhinovirus structure, classification, infections, epidemiology, and immunopathology, or that report the development of vaccines or antiviral agents. Studies that address rhinovirus infections epidemiology during the COVID-19 pandemic are particularly encouraged.

Prof. Dr. Gary McLean
Guest Editor

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