Avian Viruses and Host Immune System
A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Veterinary Vaccines".
Deadline for manuscript submissions: 1 December 2026 | Viewed by 51
Special Issue Editors
Interests: establishment of the pathogenic mechanism and detection method of the novel duck reovirus
Interests: mechanism of immunosuppression induced by avian reovirus; epidemiological trends of avian reovirus and duck reovirus; virus or virus proteins interaction with host cell; vaccine development
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Avian Reovirus is an important pathogen in the poultry industry. Natural immunity is the first line of defense against Avian Reovirus infection. It can activate natural immune signaling pathways, induce IFN and drive downstream antiviral protein expression, which is a key mechanism for the host to clear the virus. The result of this bidirectional action determines the clinical outcome of Avian Reovirus infection: if the host has a healthy immune function (e.g., adult poultry), the virus can be cleared through an efficient immune response, resulting in a latent infection; if the host has an immune deficiency (e.g., young or immunosuppressed birds), the virus continues to replicate, causing viral arthritis, immunosuppression and secondary infections, resulting in economic losses. This Special Issue will examine current research that provides targets for Avian Reovirus prevention and control (such as TLR7, MDA5, IFN pathways) and in the future, by enhancing the activity of these key immune nodes, new prevention and control technologies (such as genetic engineering vaccines, immune enhancers).
We look forward to receiving your contributions.
Dr. Tao Yun
Dr. Chengcheng Zhang
Guest Editors
Manuscript Submission Information
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Keywords
- avian reovirus
- innate immunity
- acquired immunity
- immunosuppression
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