Molecular Mechanisms of Viral Entry

Dear Colleagues,

Successful viral pathogens have sustained a long-standing association with their hosts and developed extremely complex adaptations to secure their own replication and survival. To start infection, viral particles need to invade a new host cell and deliver their genetic material. Initial steps include binding to cellular host components and membrane fusion. Several scientific breakthroughs have occurred over the last decade to help us to understand the molecular mechanisms of viral entry. Emergence of genome-wide CRISPR-Cas9 screens has allowed identification of key proteins used as viral receptors, and the recent advances in cryo-electron microscopy have generated key information at the atomic level to understand protein–protein interaction and membrane fusion.

This Special Issue of Vaccines will bring together a collection of reviews and peer-reviewed articles on cutting-edge research that focuses on detailing the molecular aspects of viral entry. Importantly, this Special Issue will also address new methodologies and tools leading to these discoveries. Perspectives, review articles, and original research articles are invited from specialists working on viral glycoproteins, cellular receptors, isolation and identification of neutralizing antibodies, and the structural and molecular aspects of virus binding and membrane fusion.

Dr. Laurent Perez
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

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