Uremic Toxins as Biomarkers in Cardiovascular Complications of Chronic Kidney Disease and Oxidative Stress
A special issue of Toxins (ISSN 2072-6651). This special issue belongs to the section "Uremic Toxins".
Deadline for manuscript submissions: closed (29 February 2024) | Viewed by 319
Special Issue Editors
Interests: biomarkers in CKD; paracrine process in vascular calcification; renal cell biology; matricellular proteins
Special Issue Information
Dear Colleagues,
It is well established that patients with chronic kidney disease (CKD) exhibit an elevated cardiovascular risk and that cardiovascular disease (CVD) is the leading cause of death in this population. We know that the accumulation of uremic toxins is associated with cardiovascular complications of CKD. The major knowledge gap exists in directly associating uremic toxins or uremia with the drivers and mechanisms of CKD-associated CVD. Addressing this gap will facilitate improved diagnosis and the development of new therapeutic approaches that will substantially improve the treatment of patients with CKD.
The aim of this Special Issue is to bring together selected articles representing recent advances and hypotheses underlying the utility of uremic toxins as predictors of progressive cardiovascular disease associated with Chronic Kidney Disease. It will contain original data supporting the theories, reports of the use of novel biomarkers, and in-depth reviews.
In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following: original data supporting mechanisms of uremia-induced cardiovascular damage, reports of the use of uremic toxins or their downstream targets as novel biomarkers, and in-depth reviews in this field.
Dr. Mark Dockrell
Dr. Nihil Chitalia
Guest Editors
Manuscript Submission Information
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Keywords
- chronic kidney disease
- cardiovascular disease
- uremic toxins
- uremia
- calcification
- ROS
- oxidative stress
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