Special Issue "Characterization and Quantitative Analysis of Botulinum Neurotoxin"
Deadline for manuscript submissions: 31 July 2019
Dr. Suzanne R. Kalb
Centers for Disease Control and Prevention, National Center for Environmental Health, Division of Laboratory Sciences, 4770 Buford Hwy, NE, Atlanta, GA 30341, USA
Botulism is caused by exposure to Botulinum neurotoxins (BoNTs), protein toxins produced by Clostridium botulinum and related Clostridia. With seven confirmed serotypes and over 40 subtypes, the diversity of these neurotoxins is both fascinating and challenging. Characterization of the varied BoNTs through qualitative analysis is critical for understanding toxicity/mechanism of action, and structure/function relationships, designing medical countermeasures to treat or prevent botulism, and development of assays to detect the neurotoxin. A quantitiative analysis of the neurotoxin assists in medical countermeasure development as well as toxicity assessments. This Special Issue will focus on qualitative and/or quantitative analysis of BoNTs as it applies to mechanism of action, toxicity assessment, structure/function relationships, medical countermeasure development, and assay development.
Dr. Suzanne R. Kalb
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxins is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Botulinum neurotoxin
- Mechanism of action
- Toxicity assessment
- Structure/function relationship
- Quantitative analysis