Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
4.5
3.9
Journals
Toxics
Special Issues
Health Effects and Toxicology Studies of Emerging Contaminants
share announcement

Health Effects and Toxicology Studies of Emerging Contaminants

A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Emerging Contaminants".

Deadline for manuscript submissions: 30 April 2025 | Viewed by 2453

Special Issue Editors

Dr. Jiufeng Li

E-Mail Website
Guest Editor
School of Public Health, Fudan University, Shanghai 200433, China
Interests: health effects of emerging contaminants; toxicology studies of emerging contaminants; method development of emerging contaminants; microplastics; endocrine disrupting chemicals (EDCs); persistent organic pollutants (POPs); omics
Dr. Yu Li

E-Mail Website
Guest Editor
School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China
Interests: reproductive and developmental toxicity of emerging contaminants; organophosphorus flame retardants (OPFRs)
Dr. Ang Li

E-Mail Website
Guest Editor
Institute of Basic Medical Sciences, Chinese Academy of Medical Science & Peaking Union Medical College, Beijing 100005, China
Interests: environmental epidemiology; heavy metal mixture; PFAS; machine learning
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In recent decades, emerging contaminants, such as microplastics, endocrine-disrupting chemicals, and persistent organic pollutants, have been found and quantified in living beings and diverse environmental substances. Hence, the adverse health effects and toxicology of emerging contaminants need to be investigated.

The scope of this Special Issue includes the following: (1) address the adverse health effects of emerging contaminants on humans, especially the sensitive population, such as the elderly, pregnant women, fetuses, and children; (2）elucidate the underlying mechanism of emerging contaminant toxicity on the basis of cell models, animal models, and organoids; (3) develop new method to identify and quantify the emerging contaminants; (4) apply omics to characterize the adverse effects and toxicity of emerging contaminants; and (5) find the functional substances to protect humans from adverse health effects of exposure to emerging contaminants.

Dr. Jiufeng Li
Dr. Yu Li
Dr. Ang Li
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • adverse health effects of emerging contaminants
  • toxicology studies of emerging contaminants
  • reproductive and developmental toxicity
  • environmental epidemiology
  • endocrine-disrupting chemicals
  • persistent organic pollutants
  • microplastics

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (3 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

21 pages, 3777 KiB  
Article
Potential Health Risk of Microplastic Exposures from Skin-Cleansing Products
by Raluca Maria Bucur (Popa), Cristiana Radulescu, Ioana Daniela Dulama, Raluca Maria Stirbescu, Ioan Alin Bucurica, Andreea Laura Banica and Sorina Geanina Stanescu
Toxics 2025, 13(5), 354; https://doi.org/10.3390/toxics13050354 - 29 Apr 2025
Abstract
This research aims to investigate and quantify the possible presence of microplastics (MPs) in usual skin-cleansing products (i.e., liquid soap, micellar water, and micellar cleansing oil), the most popular from the market in terms of brand and customer confidence. Therefore, optical microscopy and [...] Read more.
This research aims to investigate and quantify the possible presence of microplastics (MPs) in usual skin-cleansing products (i.e., liquid soap, micellar water, and micellar cleansing oil), the most popular from the market in terms of brand and customer confidence. Therefore, optical microscopy and micro-Fourier transform infrared spectroscopy (micro-FTIR) were used to determine the MPs’ number, color, shape, size, and chemical composition. For the first time, the results were correlated with the possible exposure paths (i.e., inhalation, ingestion, or adsorption) to assess the human health risk of the analyzed micellar-based cleansers in terms of chronic total exposure dose to microplastics. Finally, a statistical analysis was added to this study for source prediction of MPs in skin-cleansing samples in terms of morphology, chemical composition, and other factors (i.e., brand, packaging, etc.). The various exposures and toxicities of MPs were assessed in terms of potential health risk, knowing that their toxic effect depends on the polymeric structure strongly linked with the size, shape, and concentration in the products. Full article
(This article belongs to the Special Issue Health Effects and Toxicology Studies of Emerging Contaminants)
►▼ Show Figures

Figure 1

17 pages, 948 KiB  
Article
Concentrations of Serum Per- and Polyfluoroalkyl Substances and Lipid Health in Adolescents: A Cross-Sectional Study from the Korean National Environmental Health Survey 2018–2020
by Min-Won Shin, Habyeong Kang and Shin-Hye Kim
Toxics 2025, 13(2), 91; https://doi.org/10.3390/toxics13020091 - 25 Jan 2025
Viewed by 781
Abstract
Emerging evidence indicates that environmental exposure to per- and polyfluoroalkyl substances (PFASs) may influence lipid metabolism, though studies on adolescents remain scarce. This study aimed to investigate the association between PFAS mixture exposure and lipid profiles in Korean adolescents. Using data from the [...] Read more.
Emerging evidence indicates that environmental exposure to per- and polyfluoroalkyl substances (PFASs) may influence lipid metabolism, though studies on adolescents remain scarce. This study aimed to investigate the association between PFAS mixture exposure and lipid profiles in Korean adolescents. Using data from the Korean National Environmental Health Survey (2018–2020), we analyzed 824 adolescents aged 12–17 years. Serum concentrations of PFAS, including perfluorooctanoic acid (PFOA), perfluorooctane sulfonic acid (PFOS), perfluorononanoic acid (PFNA), perfluorohexane sulfonic acid (PFHxS), and perfluorodecanoic acid (PFDeA), and lipid profiles were assessed. In multivariate regression models, PFDeA and PFNA were positively associated with elevated total cholesterol and low-density lipoprotein cholesterol levels, and PFDeA was associated with hypercholesterolemia risk in boys. In girls, PFDeA was associated with higher high-density lipoprotein cholesterol and lower triglycerides, though no significant association with hypercholesterolemia risk was observed. Bayesian kernel machine regression demonstrated positive associations between PFAS mixture exposure and hypercholesterolemia risk in boys but not in girls. The quantile g-computation model also demonstrated an odds ratio (OR) of 1.47 (95% CI: 0.99–2.19, p = 0.057) for PFAS mixture exposure in boys, suggesting borderline statistical significance. These findings suggest that PFAS exposure may disrupt lipid metabolism, elevating hypercholesterolemia risk in adolescents, particularly boys. Full article
(This article belongs to the Special Issue Health Effects and Toxicology Studies of Emerging Contaminants)
►▼ Show Figures

Graphical abstract

18 pages, 5075 KiB  
Article
Integrative Analysis of Pharmacology and Transcriptomics Predicts Resveratrol Will Ameliorate Microplastics-Induced Lung Damage by Targeting Ccl2 and Esr1
by Yadong Zhang, Jingyi Ren, Siqi Zhu, Zihao Guo, Huanting Pei, Xiaoya Sun, Jiarui Wu, Weijie Yang, Jinshi Zuo and Yuxia Ma
Toxics 2024, 12(12), 910; https://doi.org/10.3390/toxics12120910 - 14 Dec 2024
Viewed by 1278
Abstract
Background: Microplastics (MPs) are ubiquitous on earth, posing a growing threat to human health. Previous studies have shown that the lung is a primary organ for MPs exposure. Resveratrol (RES) is a common dietary polyphenol that exhibits anti-inflammatory and antioxidant effects. However, whether [...] Read more.
Background: Microplastics (MPs) are ubiquitous on earth, posing a growing threat to human health. Previous studies have shown that the lung is a primary organ for MPs exposure. Resveratrol (RES) is a common dietary polyphenol that exhibits anti-inflammatory and antioxidant effects. However, whether RES exerts a protective effect against MPs-induced lung damage is still unknown. Methods: The targets of RES were retrieved from five databases. Differentially expressed genes (DEGs) were identified through comprehensive bioinformatic analysis. Multiple algorithms were employed to screen for the core targets. Ultimately, molecular docking analysis and molecular dynamics (MD) simulations were utilized to confirm the binding affinity between RES and the core targets. Results: In total, 1235 DEGs were identified in the transcriptomes. After removing duplicates, a total of 739 RES targets were obtained from five databases, and 66 of these targets intersected with DEGs. The potential core targets (Esr1, Ccl2) were further identified through topological analysis and machine learning. These findings were subsequently verified by molecular docking and MD simulations. Conclusions: This study demonstrated that RES may mitigate lung injury induced by MPs by targeting Esr1 and Ccl2. Our research offers a novel perspective on the prevention and treatment of MPs-induced lung injury. Full article
(This article belongs to the Special Issue Health Effects and Toxicology Studies of Emerging Contaminants)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-3
Back to TopTop