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Optical Biosensors
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Optical Biosensors

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Optical Sensors".

Deadline for manuscript submissions: closed (25 November 2024) | Viewed by 2225

Special Issue Editors

Dr. Anna Chiara De Luca

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Guest Editor
Institute of Endocrinology and Experimental Oncology “G. Salvatore” - National Research Council of Italy, Via Pietro Castellino n.111, 80131 Napoli, Italy
Interests: biophotonics; Raman spectroscopy; SERS; imaging; plasmonics; optical biosensors; nanotechnology; nanophotonics
Special Issues, Collections and Topics in MDPI journals
Dr. Genni Testa

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Guest Editor
Institute for Electromagnetic Sensing of the Environment, 80124 Napoli, Italy
Interests: integrated optical sensors; interferometric waveguide sensors; resonator waveguide sensors; sensors for biomedical application
Special Issues, Collections and Topics in MDPI journals
Dr. Marco Pisco

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Guest Editor
Department of Engineering, Università degli Studi del Sannio, 82100 Benevento, Italy
Interests: photonics; optoelectronics; optical fiber sensors
Special Issues, Collections and Topics in MDPI journals
Dr. Ilaria Rea

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Guest Editor
Institute of Applied Sciences and Intelligent Systems (ISASI), National Research Council, 80131 Napoli, Italy
Interests: nanomaterials; hybrid interfaces; photoluminescence; optical biosensors; drug delivery systems
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Optical sensing plays a vital role in the broad family of the biomedical applications offering important advantages over conventional analytical techniques because they enable the direct, real-time and label-free detection of many biological and chemical substances. Optical biosensors has witnessed rapid progress in diverse aspects, ranging, for example, from the sensor design to applications, from in vitro to in vivo measurements, from bulky optical solid-state devices to the development of novel nanomaterials. 

Aiming to bring researchers together to display their excellent works, this special issue on photonic biosensing offers a platform for providing an overview of the recent developments and strategies related to novel principles, structures or materials as well as the combinations of experimental and analytical/numerical approaches for optical biosensors. Both research articles and reviews are welcome.

Our Special Issue on optical biosensing aims to cover topics including but not limited to: the manipulation of optical transducers or the rational design of optical molecular probes, the development of new sensing materials, including a range of optical sensory device types, such as intensity based, interferometric, spectroscopic, fluorescence, colorimetric, FRET, BRET, SPR, SEIRA, SERS devices, etc., and novel applications of photonic sensors in biomedicine.

Dr. Anna Chiara De Luca
Dr. Genni Testa
Dr. Marco Pisco
Dr. Ilaria Rea
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biophotonics
  • nanomaterials
  • SERS
  • SEIRA
  • SPR
  • FRET
  • flexible biosensors
  • sensing materials
  • photonic biosensor technologies
  • lab-on-a-chip

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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Research

16 pages, 3631 KiB  
Article
Leaky Coupled Waveguide-Plasmon Modes for Enhanced Light–Matter Interaction
by Fadi Sakran, Said Mahajna and Atef Shalabney
Sensors 2025, 25(5), 1550; https://doi.org/10.3390/s25051550 - 2 Mar 2025
Viewed by 597
Abstract
Plasmon waveguide resonances (PWRs) have been widely used to enhance the interaction between light and matter. PWRs have been used for chemical and biological sensing, molecular detection, and boosting other optical phenomena, such as Raman scattering and fluorescence. However, the performances of plasmon-waveguide-based [...] Read more.
Plasmon waveguide resonances (PWRs) have been widely used to enhance the interaction between light and matter. PWRs have been used for chemical and biological sensing, molecular detection, and boosting other optical phenomena, such as Raman scattering and fluorescence. However, the performances of plasmon-waveguide-based structures have been investigated in the angular interrogation mode, and their potential in different spectral regions has hardly been explored. Moreover, the applications of PWRs have been limited to the weak light–matter coupling regime. In this study, we investigate leaky coupled waveguide plasmon resonances (LCWPRs) and explore their potential to enhance light–matter interaction in different spectral regions. In the weak coupling regime, we demonstrate the potential of LCWPRs for sensing in the near-IR region by detecting heavy water (D2O) and ethanol in water. The experimental results show spectral sensitivity of 15.2 nm/% and 1.41 nm/% for ethanol and D2O detection, respectively. Additionally, we show that LCWPRs can be used to achieve vibrational strong coupling (VSC) with organic molecules in the mid-IR region. We numerically show that the coupling between LCWPRs and the C=O stretching vibration of hexanal yields a Rabi splitting of 210 cm−1, putting the system in the VSC regime. We anticipate that LCWPRs will be a promising platform for enhanced spectroscopy, sensing, and strong coupling. Full article
(This article belongs to the Special Issue Optical Biosensors)
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21 pages, 11695 KiB  
Article
Direct Writing of Quasi-Sinusoidal and Blazed Surface Relief Optical Transmission Gratings in Bi12GeO20, Er: LiNbO3 and Er: Fe: LiNbO3 Crystals by Nitrogen Ion Microbeams of 5 MeV and 10.5 MeV Energy
by István Bányász, Gyula Nagy, Vladimir Havránek, Maria Cinta Pujol, Ágnes Nagyné Szokol, György Kármán, Robert Magnusson and István Rajta
Sensors 2025, 25(3), 804; https://doi.org/10.3390/s25030804 - 29 Jan 2025
Viewed by 624
Abstract
High diffraction efficiency optical transmission gratings with quasi-sinusoidal and saw-tooth surface relief profiles were fabricated in Bi12GeO20, Er: LiNbO3 and Er: Fe: LiNbO3 crystals by ion beam implantation. The gratings were directly written by nitrogen ion microbeams [...] Read more.
High diffraction efficiency optical transmission gratings with quasi-sinusoidal and saw-tooth surface relief profiles were fabricated in Bi12GeO20, Er: LiNbO3 and Er: Fe: LiNbO3 crystals by ion beam implantation. The gratings were directly written by nitrogen ion microbeams at energies of 5 MeV and 10.5 MeV. The finest grating constant was 4 μm. Grating constants for the majority of the gratings were 16 μm. The highest amplitudes of the gratings reached 1600 nm. The highest first-order diffraction efficiency obtained in a sinusoidal grating was 25%, close to the theoretical maximum of 33%. The highest first-order diffraction efficiency of a blazed grating was also 25%, without Littrow optimization. Such gratings can be incorporated into integrated optical biosensors. Full article
(This article belongs to the Special Issue Optical Biosensors)
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