Special Issue "Amperometric Biosensors"


A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".

Deadline for manuscript submissions: 31 October 2014

Special Issue Editor

Guest Editor
Dr. Roberto Pilloton
1st Researcher at CNR Institute for Atmospheric Pollution CNR - Via Salaria km 29, 300, Monterotondo, Rome, Italy
Website: http://www.biosensing.net
E-Mail: pilloton@iia.cnr.it
Phone: +39 06 49935282
Fax: +39 06 41522270
Interests: electrochemistry, environmental analytical chemistry; biosensors; sensors and sensing; continuous flow monitoring; immobilization techniques; enzyme inhibitors; lab on a Chip; nanostructured electrodes; screen printed electrodes; herbicides; pesticides; phenolic compounds; cholinesterases; photosystem II; laccase; tyrosinase; immobilized cells

Special Issue Information

Dear Colleagues,

More than 50 years ago, Clark and Lyons created the first biosensor: a glucose amperometric sensor. They coupled a Clark amperometric sensor for dissolved oxygen with an enzyme, glucose oxidase, which was immobilized on the tip of the electrode with a cellophane membrane. This method of bio-quantitative-assaying was simple, quick, and cheap. In subsequent pioneering years, the assay was extensively and profitably developed for diabetes monitoring.

Since that time, many improvements and applications were developed to not only increase the analytical performance of these amperometric biosensors, but also to prolong the lifetime of several immobilized biological molecules. Developments concerned such molecules’ oriented immobilization, the miniaturization of transducers, and automated, long-term monitoring applications with respect to several fields, which range from medicine, to environmental science and food quality studies.

Currently, improvements in amperometric biosensors mainly concern new materials for disposable electrodes, their deposition techniques (i.e., screen and ink-jet printing) and nanostructures (i.e., nanoelectrode ensembles), engineered sensing biological molecules, their electrochemical addressing and reversible and oriented immobilization, micro-fluidic devices, and Lab-on-a-Chip devices. These improvements reflect the cross interaction of several disciplines and technologies, which range from (without being exhaustive) chemistry, biology, physics, and molecular biology, to nanotechnology, micro-fabrication, and electronic engineering.

This Special Issue aims to bring together articles discussing innovative applications of amperometric biosensors, and to share the benefit of these new ideas and concepts, which are employed in multiple fields, with authors and readers of the journal, who have varying interests.

Both review articles and original research papers relating to the application of amperometric biosensors are solicited.

Dr. Roberto Pilloton
Guest Editor


Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed Open Access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs).


  • amperometric biosensors
  • nanostructured particles and electrodes
  • carbon nanotubes and graphene
  • engineered molecules or microorganisms
  • continuous flow monitoring
  • immobilization techniques
  • lab on a chip
  • screen printed electrode

Published Papers (4 papers)

Sensors 2014, 14(3), 4634-4656; doi:10.3390/s140304634
Received: 17 December 2013; in revised form: 28 February 2014 / Accepted: 5 March 2014 / Published: 7 March 2014
Show/Hide Abstract | Download PDF Full-text (711 KB)

Sensors 2014, 14(2), 3756-3767; doi:10.3390/s140203756
Received: 10 December 2013; in revised form: 24 January 2014 / Accepted: 8 February 2014 / Published: 24 February 2014
Show/Hide Abstract | Download PDF Full-text (376 KB) | View HTML Full-text | Download XML Full-text
abstract graphic

Sensors 2014, 14(2), 3543-3556; doi:10.3390/s140203543
Received: 29 November 2013; in revised form: 28 January 2014 / Accepted: 12 February 2014 / Published: 20 February 2014
Show/Hide Abstract | Download PDF Full-text (711 KB) | View HTML Full-text | Download XML Full-text

Sensors 2014, 14(2), 2578-2594; doi:10.3390/s140202578
Received: 10 December 2013; in revised form: 26 January 2014 / Accepted: 27 January 2014 / Published: 7 February 2014
Show/Hide Abstract | Download PDF Full-text (369 KB) | View HTML Full-text | Download XML Full-text
abstract graphic

Last update: 3 February 2014

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