Electrochemical DNA- and Aptasensors for the Detection of Low-Molecular Compounds (2nd Edition)
A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".
Deadline for manuscript submissions: 25 April 2026 | Viewed by 4
Special Issue Editor
Interests: biosensors; DNA aptamers; electrochemistry; molecular acoustics; model membranes; nanomaterials; nanoparticles
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Electrochemical DNA- and aptasensors have attracted increasing attention in the past few decades due to the promising applications in the framework of the point-of-care (point-on-demand) concept outside the chemical laboratory. They are intended for the fast and reliable detection of many species demanded in medicine (metabolites, drugs, oncomarkers), the food industry (vitamins, antioxidants, food additives, veterinary drugs), and environmental monitoring (pesticides, DNA-damaging contaminants, heavy metals, detergents). The assembly of DNA sensors, including the design of biorecognition elements and new approaches to signal amplification, calls for new materials based on the achievements of supramolecular chemistry, nanotechnology, and self-assembly. In the Special Issue, the following topics are mostly welcome, both as reviews and research articles:
- The design of DNA- and aptasensors based on new modifiers and assembling protocols (carbon nanomaterials, MOFs, MIPs, polyelectrolyte layers, hybrid coatings with metals and their compounds (oxides, complexes)
- Application of new mediator systems to enhance the electrochemical signals, and development of robust biosensors
- Biochemical systems of signal amplification, E-sensor design
- Multiplex analysis with electrochemical DNA- and aptasensors
- Miniaturization and automation prospects for low-molecular analyte detection, electrochemical microfluidics, and flow-injection analysis, origami biosensors
- Sampling and sample treatment, validation of electrochemical DNA- and aptasensors for real sample analysis
- Future prospects in the design of biorecognition elements (chimeric DNA, protein nucleic acids, hybrid immuno/DNA sensors)
The topic of this Special Issue aligns closely with the scope of Sensors, covering essential aspects of biosensor development and application, ranging from recognition element design and surface layer assembly to measurement condition optimization and real sample analysis. The design of portable sensors remains a highly relevant and dynamic field due to their evident advantages and broad potential for innovation.
To view the first edition of this Special Issue, please visit:
https://www.mdpi.com/journal/sensors/special_issues/NUN8U0ET4S
Prof. Dr. Tibor Hianik
Guest Editor
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Keywords
- electrochemical dna sensors
- aptasensors
- low-molecular-weight compounds
- signal amplification
- real sample detection
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