Special Issue "Biocatalysis, Enzyme and Process Engineering"
Deadline for manuscript submissions: closed (31 December 2020).
Interests: bacterial adaptation; marine biotechnology; biocatalysis; bioreactors; bioprocess engineering
Special Issues and Collections in MDPI journals
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Enzymes are acknowledged as effective catalysts, namely, on account of their selectivity, high turnover, and ability to operate under mild conditions. Despite these advantageous features, the industrial application of enzymes still lags behind their use on a laboratory scale. This pattern may be partly assigned to the intrinsic nature of enzymes: these biocatalysts have been optimized throughout the ages to be mostly active in aqueous media and to operate in environments where substrate and product concentrations are much lower than those required for industrial processes to be commercially feasible. Hence, high concentrations of substrates or products can be toxic or inhibitory. Moreover, the compounds involved in several of these industrial processes, namely, in the pharmaceutic industry, are often sparingly water-soluble, hence the need to use non-aqueous media, which can pose limitations on several enzymes. Enzyme engineering, often coupled to process engineering, has been shown to provide a sound approach to tackle these issues and improve the catalytic and stability features of several enzymes. In addition, methodologies such as continuous flow, already well-established in chemical processes, have been increasingly used in biocatalysis, given their potential to increase overall bioconversion rates due to increased mass transfer and enhanced throughput of material.
This Special Issue on “Biocatalysis, Enzyme, and Process Engineering” aims to address novel advances in the development and application of enzymes in the production of goods of interest for large-scale production. Topics include but are not limited to the following:
- Enzyme engineering towards improved biocatalysts;
- The development of novel process designs for biocatalysis;
- Multienzyme cascade reactions.
Dr. Pedro Fernandes
Dr. Carla C. C. R. de Carvalho
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Processes is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- cascade reactions
- continuous flow
- directed evolution
- enzyme engineering
- multiphase systems
- rational design
- white biotechnology