Dear Colleagues,

We would like to invite you to submit your excellent work in the synthesis, characterisation and application of smart polymeric nanoparticles in nanomedicine to this special issue of Polymers.

Polymer chemists have significantly contributed to the field of nanomedicine by developing new synthesis methods to produce novel polymers and innovative self-assembly techniques (e.g., polymerization-induced self-assembly (PISA) or temperature-induced self-assembly (TMIT)) to prepare polymeric nanoparticles. Importantly, these polymeric nanoparticles can respond to stimuli (e.g., pH, temperature, light, magnetic field, reactive oxygen species (ROS), etc.) or self-degrade in a controlled manner to release therapeutics encapsulated (drugs, siRNA, mRNA, pDNA, protein, enzyme, etc.).  These particles can also be functionalised with biomolecules and hence can target or bind to the targeted cells.

Despite the initial tremendous success of the field, polymeric nanoparticles are still far from perfect, and the majority of the nanoparticle systems developed have not been successfully translated to the clinic. Therefore, extra efforts from the polymer chemist community are urgently needed to develop better polymeric nanoparticles for a variety of clinical applications in nanomedicine.

This Special Issue aims to highlight outstanding work and review articles that will advance the field nanomedicine. All manuscripts reporting the novel synthesis, characterisation and application of smart polymeric nanoparticles and their hybrids (with inorganic nanomaterials, lipids, etc.) are welcome.

We look forward to receiving your high-quality manuscript.

Dr. Nghia P. Truong
Dr. Joaquin Sanchis Martinez
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• Nanoparticles
• Stimuli responsive, smart, hybrid, nanomedicine
• Drug delivery
• Diagnostics
• MRI
• Release
• Diseases