Synthesis and Applications of Functional Polymer Nanocarriers

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Polymer Processing and Engineering".

Deadline for manuscript submissions: closed (31 March 2022) | Viewed by 5675

Special Issue Information

Dear Colleagues,

Their small size, unusually large specific surface, diversity of chemical composition, ability of production with varied architectures, and suitability for controlled self-assembly make polymer and polymer–inorganic functional nanocarriers unique nanotransporters and nanotools useful in medicine and modern technologies. In medicine, functional nanocarriers are used as basic elements of smart drug delivery systems, ensuring transportation of bioactive substances to designated tissues, cells, and intracellular compartments. During transportation in nanocarriers, the bioactive substances are protected from often highly undesired interactions with organs other than the targeted ones. Functional nanoparticles are considered as important components of diagnostic devices and elements of teranostic systems combining therapeutic and diagnostic functions. In biotechnology, functional nanoparticles and nanocapsules are used as carriers of enzymes and as nanoreactors. There are studies on the application of functional polymer nanocarriers for many other applications, among them for the fabrication of soft solar energy harvesting flexible films, preparation of polymer colloidal crystals for photoelectronics, and for smart coatings transmitting visible light and reflecting infrared radiation (for intelligent windows). For the abovementioned applications and for the variety of others, polymer functional nanocarriers with properly tailored properties are needed. This Special Issue shall gather original and review papers that mainly discuss achievements from the last five years on polymer nanocarrier preparation, characterization, and properties enabling development of better nanomaterials for the already existing as well as for emerging new applications. We hope that the papers of this Issue will inspire researchers in their own work.

Prof. Dr. Stanislaw Slomkowski
Dr. Ana Grenha
Dr. Noelia Flórez-Fernández
Guest Editors

Manuscript Submission Information

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Keywords

  • Polymer nanocarriers
  • Functional nanocarriers
  • Polymer micelles
  • Polymer nanovesicles
  • Nanocarriers of bioactive compounds,
  • Drug delivery
  • Nanocarriers of therapeutic nucleic acids
  • Nanocarriers of oligopeptides and proteins
  • Nanoparticles for medical diagnostics
  • Targeted deliveryStimuli-induced release

Published Papers (1 paper)

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Review

26 pages, 4757 KiB  
Review
Thermosensitive Polymers and Thermo-Responsive Liposomal Drug Delivery Systems
by Waad H. Abuwatfa, Nahid S. Awad, William G. Pitt and Ghaleb A. Husseini
Polymers 2022, 14(5), 925; https://doi.org/10.3390/polym14050925 - 25 Feb 2022
Cited by 32 | Viewed by 5249
Abstract
Temperature excursions within a biological milieu can be effectively used to induce drug release from thermosensitive drug-encapsulating nanoparticles. Oncological hyperthermia is of particular interest, as it is proven to synergistically act to arrest tumor growth when combined with optimally-designed smart drug delivery systems [...] Read more.
Temperature excursions within a biological milieu can be effectively used to induce drug release from thermosensitive drug-encapsulating nanoparticles. Oncological hyperthermia is of particular interest, as it is proven to synergistically act to arrest tumor growth when combined with optimally-designed smart drug delivery systems (DDSs). Thermoresponsive DDSs aid in making the drugs more bioavailable, enhance the therapeutic index and pharmacokinetic trends, and provide the spatial placement and temporal delivery of the drug into localized anatomical sites. This paper reviews the fundamentals of thermosensitive polymers, with a particular focus on thermoresponsive liposomal-based drug delivery systems. Full article
(This article belongs to the Special Issue Synthesis and Applications of Functional Polymer Nanocarriers)
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