Chitosan, Its Derivatives and Nanoparticles Based on Chitosan: Synthesis, Characterization and Application, 2nd Edition
A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Biobased and Biodegradable Polymers".
Deadline for manuscript submissions: 15 April 2025 | Viewed by 8520
Special Issue Editors
Interests: biopolymers; chitosan; chitosan derivatives; nanoparticles; antibacterial activity; fungicidal activity
Special Issues, Collections and Topics in MDPI journals
Interests: polysaccharides; chitosan; chitosan derivatives; nanoparticles; antimicrobial activity
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The scientific community is now focusing on the use of eco-friendly materials to reduce the environmental impact of synthetic materials. Eco-friendly materials include polymers of natural origin. Chitosan is one such promising biopolymer with a wide range of applications. It has unique properties, such as biodegradability, biocompatibility, low toxicity, antimicrobial activity, and source availability. The presence of hydroxyl and amino functional groups in the chitosan molecule enables chitosan to be chemically modified, expanding its potential applications. Nanomaterials have many applications due to their superior physical and chemical properties compared to bulk materials. These properties are due to the increased surface-to-volume ratio and surface energy of the miniature particles. Chitosan nanoparticles have high functionalization potential and drug-loading capability and antimicrobial properties while remaining biodegradable and biocompatible.
This Special Issue "Chitosan, Its Derivatives and Nanoparticles Based on Chitosan: Synthesis, Characterization and Application" will focus on various fundamental and applied research of chitosan, its derivatives and nanoparticles and their biomedical and biotechnological applications, including in agriculture.
Topics will include, but are not limited to, the following:
- Chitosan derivatives, synthesis, characterization and applications;
- Chitosan-based nanoparticles, synthesis, characterization, and applications;
- Antimicrobial activity of chitosan and chitosan nanoparticles;
- Application of chitosan-based materials, including nanoparticles in biomedicine and agriculture.
Dr. Balzhima Shagdarova
Dr. Alla V. Il'ina
Guest Editors
Manuscript Submission Information
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Keywords
- biopolymer
- chitosan
- chitosan derivatives
- nanoparticles
- composites
- antibacterial activity
- fungicidal activity
- biomedicine
- agriculture
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Planned Papers
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Title: Effect of Chitosan Derivatives on Olanzapin Induced Metabolic Syndrome in Oral Model
Authors: Balzhima Shagdarova1,*,Viktoria Melnikova2, Valentina Kostenko3, Mariya Konovalova3, Valery Varlamov1, Elena Svirshchevskaya3
Affiliation: 1 Institute of Bioengineering, Research Center of Biotechnology of the Russian Academy of Sciences, Moscow 119071, Russia;
2 Koltzov Institute of Developmental Biology Russian Academy of Sciences, Moscow 119334, Russia;
3 Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences 117997 Moscow, Russia;
Abstract: Olanzapine (OLA) is an antipsychotic drug for the treatment of schizophrenia and bipolar disorder. OLA often causes an increase in body mass. The search and development of natural compounds for the prevention of obesity during antipsychotic therapy is an urgent task. The polysaccharide chitosan (CH) and its derivatives have lipid-lowering and antidiabetic properties. Chemical modification of chitosan makes it possible to obtain derivatives with increased solubility in vivo, which makes them potential therapeutic substances for use in the treatment of metabolic disorders. The aim of this work was to analyze the effect of the natural biopolymer CH and N-succinyl chitosan (SCH) on OLA-induced metabolic changes in an oral mouse model. CH was obtained by chemical hydrolysis and was used to synthesize SCH. Mice were fed cereals mixed with OLA or combinations OLA + CH, OLA+SCH, OLA + orlistat (ORL), as a control, for 2 months. In response dynamics, the weight of mice, amount of food and water intake, levels of triglycerides, cholesterol, amount of fat, and expression of genes associated with appetite regulation in the hypothalamus of mice were analyzed. It was shown that OLA induced an increase in weight, food uptake, triglycerides and cholesterol levels as wells as affected some gene expression. ORL did not affect food intake but decreased the weight of mice. CH and SCH decreased both the food uptake and the weight of mice.
Title: Chitosan based composite for oral applications
Authors: Martha Chuc-Gamboa; Fernando Aguilar-Perez
Affiliation: Universidad Autonoma de Yucatan
Title: Removal of Phosphate Using Copper Loaded Chitosan: A Sustainable Method of Wastewater Treatment
Authors: Haya Alyasi; Alaa Elsafi Ahmed; Gordon McKayc*
Affiliation: 1. Qatar Environment and Energy Research Institute (QEERI), Hamad Bin Khalifa University (HBKU), P.O. Box 5825, Doha, Qatar
2. Materials Science and Technology Program, Department of Mathematics, Statistics and Physics, College of Arts and Sciences, Qatar University, P.O. Box 2713, Doha, Qatar
3. Division of Sustainable Development, College of Science and Engineering, Hamad Bin Khalifa University, Education City, Qatar Foundation, Doha, Qatar.
Title: Chitosan siRNA Nanoparticles Produce Significant Non-toxic Functional Gene Silencing in Kidney Cortices
Authors: Mohamad-Gabriel Alameh1,2; Ashkan Tavakoli Naeini1; Garima Dwivedi1; Frederic Lesage1,2; Michael D. Busch-mann1,2; Marc Lavertu1,2
Affiliation: 1 Polytechnique Montreal, Institute of Biomedical Engineering, 2500 Chem. de Polytechnique, Montréal, QC H3T 1J4, Canada
2 Polytechnique Montreal, Department of Chemical Engineering, 2500 Chem. de Polytechnique, Montreal, QC, Canada.