Molecular Biology of Fruit Development

A special issue of Plants (ISSN 2223-7747). This special issue belongs to the section "Plant Molecular Biology".

Deadline for manuscript submissions: 31 December 2026 | Viewed by 219

Special Issue Editors


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Guest Editor
Key Laboratory of Biology and Genetic Improvement of Horticulture Crops (Northeast Region), Ministry of Agriculture and Rural Affairs, College of Horticulture and Landscape Architecture, Northeast Agricultural University, Harbin 150006, China
Interests: fruit crop; watermelon; physiological traits; drought tolerance; gene family; functional gene

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Guest Editor
School of Enology and Horticulture, Ningxia University, Yinchuan 750021, China
Interests: vegetable genetic breeding and biotechnology; creation of mutants and development of molecular markers; genetic characteristics and molecular mechanisms; functional characterization of key genes

Special Issue Information

Dear Colleagues,

Fruit development is a complex and highly regulated process encompassing fruit set, growth, maturation, ripening, senescence, and abscission. It is governed by sophisticated molecular networks involving genetic, epigenetic, hormonal, and environmental signals. Understanding the molecular basis of fruit development is critical for improving fruit yield, quality, nutritional value, shelf life, and stress resistance, and provides a theoretical foundation for molecular breeding of horticultural crops.

This Special Issue aims to collect cutting-edge research on the molecular regulatory mechanisms underlying fruit development. It focuses on revealing gene functions, non-coding RNA regulation, epigenetic modifications, hormone signaling crosstalk, transcription factor networks, and responses to environmental cues during fruit growth and ripening. We welcome studies covering model plants, horticultural fruit crops, and other fruit-bearing species, and we strive to publish high-quality original research and review articles that advance the field.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:

  • Molecular regulation of fruit set and early development.
  • Cell division and expansion during fruit growth.
  • Transcriptional and post-transcriptional regulation of fruit development.
  • Epigenetic regulation (DNA methylation, histone modification, and chromatin remodeling).
  • Phytohormone signaling and crosstalk in fruit development.
  • Molecular mechanisms of fruit ripening and senescence.
  • Fruit quality formation and nutritional metabolism.
  • Environmental and stress responses in fruit development.
  • Genomic and transcriptomic studies of fruit development.
  • Molecular breeding for fruit quality and yield improvement.

We look forward to receiving your contributions.

Prof. Dr. Xuezheng Wang
Dr. Guoxin Cheng
Guest Editors

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Keywords

  • fruit development
  • molecular regulation
  • fruit ripening
  • hormone signaling
  • transcription factor
  • epigenetic modification
  • gene function
  • fruit quality
  • horticultural crop
  • molecular breeding

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Published Papers (1 paper)

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Research

14 pages, 15345 KB  
Article
Integrated Analysis of DNA Methylation and Transcriptomic Dynamics in the Grape Variety ‘Cabernet Franc’ at Early and Late Stages of Fruit Development
by Qingtian Zhang, Shouming Shan, Xiaoyu Zhou, Pengfei Wang, Zhaobo Lang, Yujing Lin, Wei Ji and Ao Li
Plants 2026, 15(12), 1815; https://doi.org/10.3390/plants15121815 - 12 Jun 2026
Abstract
DNA methylation is a key epigenetic regulator in plant development. However, the changes in methylation patterns between the early and late stages of grape berry development, the two phases with the most pronounced morphological differences, and the respective roles of methylation at these [...] Read more.
DNA methylation is a key epigenetic regulator in plant development. However, the changes in methylation patterns between the early and late stages of grape berry development, the two phases with the most pronounced morphological differences, and the respective roles of methylation at these stages remain largely unexplored. To investigate the dynamic DNA methylation changes during this stage and their regulatory role in fruit development, we constructed genome-wide methylation maps of grape at two key time points: the early development stage (7 days after flowering, 7DAF; hereafter referred to as S1) and the late development stages (78 days after flowering, 78DAF; hereafter referred to as S2). Global cytosine methylation increased from 12.57% (S1) to 14.16% (S2), driven primarily by a substantial increase in CHH methylation (from 5.88% to 7.92%; p < 0.001), whereas CG and CHG methylation showed no statistically significant change. Most differentially methylated regions (DMRs) were hypermethylated in S2, predominantly in the CHH context. Integrative methylome and transcriptome analysis revealed that CHH hypermethylation was associated with the downregulation of YABBY5 (a berry size repressor) and upregulation of UGPase (a cell wall biosynthesis gene), suggesting a potential regulatory role in fruit expansion. Because our study compares only two time points, it cannot distinguish between gradual and stage-specific methylation changes, and functional validation of the identified genes is required. Nevertheless, these findings provides a valuable resource for understanding stage-specific DNA methylation dynamics and their association with gene expression during grape berry development. Full article
(This article belongs to the Special Issue Molecular Biology of Fruit Development)
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