Extracellular Vesicle-Based Delivery System for Cancer and Neurodegenerative Disease Treatment
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Gene and Cell Therapy".
Deadline for manuscript submissions: 31 July 2025 | Viewed by 2178
Special Issue Editors
Interests: extracellular vesicles; cargo; cancer
Interests: nanovaccines; nanomaterials; cancer immunotherapy; nanomedicine; mRNA-based immunotherapy; drug and gene delivery; non-viral vectors
Special Issues, Collections and Topics in MDPI journals
Interests: nanomedicine; drug delivery; scanning force microscopy; cytomechanics; nanocarriers
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
We are pleased to invite you to contribute to our Special Issue on “Extracellular Vesicle-Based Delivery System for Cancer and Neurodegenerative Disease Treatment”.
Extracellular vesicles (EVs) have emerged as promising nanocarriers capable of crossing biological barriers and delivering therapeutic agents with high specificity and reduced toxicity. The most clinically approved delivery vehicles are represented by liposomes, which are EV-like structures sharing structural similarities with EVs but differing in composition and ease of production. EVs offer greater biological complexity and potential for drug loading but face manufacturing and quality control challenges. Future applications involve the use of EV-based platforms for the delivery of immunotherapeutics, such as mRNA-based drugs. Overall, the field of EVs could be critical for advancing targeted therapies, which can significantly contribute to improving the outcomes of patients with cancer or neurodegenerative conditions.
This Special Issue aims to gather innovative research and comprehensive reviews on the development and application of EV-based delivery systems. We seek to explore the mechanisms, challenges, and clinical potential of these systems (by EVs and EV-like structures), aligning with cutting-edge therapeutic strategies and drug/gene delivery technologies.
In this Special Issue, we welcome original research articles and reviews. Research areas may include (but are not limited to) the engineering of EVs for drug delivery, therapeutic applications in cancer and neurodegenerative diseases, and clinical translation of EV-based therapies.
We look forward to receiving your contributions.
Dr. Eva Costanzi
Dr. Stefano Persano
Prof. Dr. Stefano Leporatti
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- extracellular vesicles
- liposomes
- cancer
- neurodegenerative diseases
- immunotherapy
- mRNA delivery
- drug delivery system
- therapeutics
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