Polymer Therapeutics: From Synthesis to Biomedical Applications
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".
Deadline for manuscript submissions: closed (31 March 2022) | Viewed by 27237
Special Issue Editors
Interests: polymeric nanoparticles; antibody conjugate nanoparticles; breast cancer; biodegradable polymers; metallodrugs
Special Issues, Collections and Topics in MDPI journals
Interests: physical chemistry; photonics; time resolved fluorescence spectroscopy; fluorescence microscopy; nanotechnology; cancer; nanomedicine; biosensors
Special Issues, Collections and Topics in MDPI journals
Interests: supramolecular chemistry; polymer processing; biopolymers; structure-properties relationship; x-ray scattering; SAXS/WAXS; soft matter; polymer physics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The intimate relationship between molecular design and polymer applications has been largely exploited to attain functional materials with targeted responsive properties upon specific external stimuli. Particularly, the synthesis of biocompatible polymeric systems with biomedical and pharmaceutical applications is a challenging task that requires complex molecular architectures featuring ambivalent properties to efficiently fulfil therapeutic function and smart drug administration while retaining the pharmaceutical activity at industrial processing conditions.
Primarily, the specific drug uptake and controlled therapeutic release are harnessed from both supramolecular concepts and physicochemical phenomena to entrap the therapeutic agent with concepts such as host/guest molecular recognition and binding and the posterior drug release by various mechanisms assisted by biodegradation with external local physicochemical conditions.
Likewise, therapeutic polymers emerge as polymers with pharmaceutical and biomedical applications. The definition encompasses polymeric molecules that are naturally pharmaceutically active, polymers conjugated with the drug or with biomacromolecules such as proteins, polymeric nanoparticles or polymeric micellar systems, up to targeted polymeric systems conjugated with antibodies, tissue engineering, and polymers in orthopedic implants.
Herein, the current advances in the state of the art of novel therapeutic polymers are highlighted from the design, synthesis, physicochemical characterization, and processing to applicability in pharmacy and biomedicine.
Dr. Carlos Alonso-Moreno
Dr. Iván Bravo Pérez
Dr. Daniel Hermida-Merino
Guest Editors
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Keywords
- polymer therapeutics
- drug delivery systems
- supramolecular smart polymeric systems
- biomedicine
- polymer processing
- biodegradation
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