Nanotechnology in Ocular Drug Delivery
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".
Deadline for manuscript submissions: closed (31 August 2022) | Viewed by 22882
Special Issue Editors
Interests: ocular drug delivery; non-aqueous; eye drops; dry eye disease; topical
Interests: long-acting drug delivery systems; microneedles; ocular drug delivery; polymer/peptide synthesis; 3D printing
Special Issue Information
Dear Colleagues,
The eye, although seemingly easy to access, is a complex and dynamic organ that presents unique challenges for drug delivery. With formidable tissue barriers and a rich perfusion of blood vessels, the eye significantly restricts the entry of foreign substances; meanwhile, due to its vulnerable nature, the toxicity and irritation potential of conventionally used formulations and excipients are often heightened. As such, ocular drug delivery is essentially a compromise between safety and efficacy.
In recent years, “nanomedicine” has been extensively investigated due to its proposed advantages of sustained and targeted drug delivery, reduced adverse effects, and enhanced bioavailability of hydrophobic and hydrophilic drugs, macromolecules, proteins, and peptides as well as biological vectors, including genes and antibodies. Thus, nanotechnology may facilitate the delivery of ocular therapeutics in clinically relevant concentrations to the anterior, and possibly even posterior, ocular tissues.
This Special Issue highlights new and emerging research in nanomedicine for both the topical and intraocular administration of ocular therapeutics and its application in the treatment and management of ocular pathologies.
Dr. Priyanka Agarwal
Prof. Dr. Thakur Raghu Raj Singh
Guest Editors
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Keywords
- nanotechnology
- ocular drug delivery
- topical administration
- nanoparticles
- micelles
- liposomes
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