Special Issue "Microencapsulation Technology Applied to Pharmaceutics 2014"
A special issue of Pharmaceutics (ISSN 1999-4923).
Deadline for manuscript submissions: closed (25 January 2014)
Prof. Dr. Denis Poncelet
Oniris, rue de la géraudière, BP 82225, 44322 Nantes, France
Phone: +33 2 51 78 54 25
Interests: bioencapsulation; solid dispersion
Prof. Dr. Thierry Vandamme
Laboratory for the Conception and Application of Bioactive Molecules, UMR 7199 CNRS, Faculty of Pharmacy, University of Strasbourg, France
Interests: the design and the formulation of drugs by using microencapsulation technologies; in vitro / in vivo drug release and mathematical modeling; controlled release of drugs from different raw materials allowing sustained release or targeting; application for different administration routes
Dear Colleagues,Microencapsulation is one of the techniques able to overcome the drug stability problem, and moreover, the possibility of formulating encapsulated drug delivery systems with controlled release rates. On these bases, microencapsulated dosage forms represent effective new therapeutic platforms. The active molecules are protected as long as they reach their specific action site. Most of the applied techniques of micro-encapsulation are based on modifications of the three basic methods: spray-drying, phase separation (coacervation), and solvent extraction/evaporation.
This special issue will cover the different interests of microencapsulation as a means to control or modify the release of drug substances from drug delivery systems. Since clinical efficacies have been reported to be improved by the encapsulation of pharmaceuticals, the bioavailability of drugs, control drug release kinetics, minimizing drug side effects, and taste masking of the bitter taste of drug substances will be discussed.
Similar special issue can be found at follwing link:
Prof. Dr. Denis Poncelet
Prof. Dr. Thierry Vandamme
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed Open Access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 500 CHF (Swiss Francs). English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.
- encapsulation efficiency
- lipid formulation
- water-in-oil emulsion
- emulsion solvent evaporation
- membrane emulsification
- size controlled emulsion
- drug; targeting
- polymeric drug delivery systems
- taste masking
- self microemulsifying
Article: Preparation of Microcapsules Containing β-Carotene with Thermo Sensitive Curdlan by Utilizing Reverse Dispersion
Pharmaceutics 2013, 5(4), 609-620; doi:10.3390/pharmaceutics5040609
Received: 26 September 2013; in revised form: 30 October 2013 / Accepted: 12 November 2013 / Published: 21 November 2013| Download PDF Full-text (469 KB) | Download XML Full-text
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Title: Hollow Pollen Shells to Enhance Drug Delivery
Authors: Alberto Diego-Taboada*, Stephen T. Beckett, Stephen L. Atkin and Grahame Mackenzie
Affiliation: University of Hull and Sporomex
Abstract: Pollen grain and spore shells are natural microcapsules designed to protect the genetic material of the plant from external damage. The shell is made up of two layers, the inner layer (intine) made of cellulose and the outer layer (exine) composed mainly of sporopollenin. The relative proportion of each varies according to the plant species. The structure of sporopollenin has not been fully characterised but different studies suggest the presence of conjugated phenols, which provide antioxidant properties to the microcapsule and UV protection to the material inside it. These microcapsule shells have many advantageous properties such as homogeneity in size, resilience to both alkalis and acids and ability to withstand temperatures up to 250 °C. These hollow microcapsules have the ability to encapsulate and release actives in a controlled manner. Their mucoadhesion to intestinal tissues keeps the sporopollenin for an extended period within the gut, increasing the efficiency of delivery of nutraceuticals and drugs. The hollow microcapsules can be filled with a solution of the active or active in a liquid form by simply mixing both together and in some cases operating a vacuum. The payload can be released in the human body depending on its solubility and/or pH and this release can be controlled by adding a coating on the shell or co-encapsulation with the active inside the shell.
Keywords: Sporopollenin; exines; pollen; antioxidant; UV protection; porous shells; high loading; controlled release; bioavailability
Last update: 3 February 2014