Special Issue "Cyclodextrins in Drug Delivery"
Deadline for manuscript submissions: 31 May 2021.
Interests: cyclodextrins complexes; dissolution; nanocarriers as drug delivery systems; drug-in cyclodextrin-in nanocarrier; transmucosal delivery
Interests: cyclodextrins; drug delivery systems; drug-in-cyclodextrin-in-nanolipid carriers; oral administration; pediatric formulations; topical delivery
Special Issues and Collections in MDPI journals
Special Issue in Applied Sciences: Cyclodextrin-Based Materials and Applications
Cyclodextrins are one of the most versatile tools in pharmaceutical technology, due to their unique structural conformation. They are cyclic oligosaccharides consisting of (α-1,4-)-linked α-D-glucopyranose units with a hydrophilic outer surface and a hydrophobic central cavity, able to form non-covalent inclusion complexes with a wide range of molecules, including a variety of drugs. They are also able to form a variety of supramolecular structures (self-assembling systems, poly(pseudo)rotaxanes, cross-linked networks). Moreover, natural cyclodextrins can be opportunely derivatized and/or functionalized to further extend and enhance their possible applications.
Cyclodextrins play a very important role in formulation by improving drug solubility and/or dissolution, permeability, and physical and chemical stability, thus enhancing their bioavailability. Other applications include odor and taste masking, prevention of incompatibility, and control of drug release.
Moreover, their combined use with various nanocarriers can be an interesting approach to simultaneously increase the performance of both as drug carriers.
Due to their multifunctional properties, cyclodextrins can be exploited in the development of almost every kind of drug delivery system, aimed for oral, transdermal, parenteral, ocular, nasal, or rectal administration.
Authors are kindly invite to submit original papers, communications and reviews regarding potential applications of cyclodextrins in drug delivery, to be published in this Special Issue of Pharmaceutics.
Prof. Dr. Paola Mura
Prof. Dr. Marzia Cirri
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.
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- drug delivery
- inclusion complexes
- supramolecular structures
- drug-in cyclodextrin-in nanocarrier