Application of Gold Nanoparticles and Gold-Based Polymer Composites in Biomedicine
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".
Deadline for manuscript submissions: closed (25 December 2021) | Viewed by 31040
Special Issue Editors
Interests: drug delivery; electrospinning; layer-by-layer; scaffolds; wound dressings; antimicrobial coatings; hydrogels; polysaccharides; cytocompatibility; hemocompatibility; polymer-based composites; metallic nanoparticles; mammalian cells
Special Issues, Collections and Topics in MDPI journals
Interests: polysaccharides; tissue engineering; blood–material interactions; orthopedic applications; protein–surface interactions; nanomaterials
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Gold nanoparticles (AuNPs) are cytocompatible and have enormous potential for biomedical application. We highlight cancer treatments using photothermal and imaging therapies and cancer diagnosis due to localized surface plasmon resonance properties. Because of their high surface area to volume ratios, AuNPs often present instability in body fluids. Proteins and ionic species interact with AuNPs, promoting aggregation. To overcome this disadvantage, AuNP-based polymer composites are created, following ex-situ and in-situ strategies. Polymers stabilize AuNPs due to hindrance and repulsion forces supported by ionized sites on polymer-capping agents. Polymers can also coordinate with AuNPs, protecting them against aggregation. Biopolymers improve biomedical AuNP response, providing durability and enhanced cytocompatibility. Polymer-stabilized AuNP composites are used as drug delivery devices, sensors, scaffolds, wound dressings, coatings, and materials for nonconventional cancer therapies.
This Special Issue invites researchers to submit papers concerning AuNPs and AuNP/polymer composites applied as drug delivery platforms, photothermal and imaging agents, biosensors, wound dressings, scaffolds, and antimicrobial coatings, highlighting the progress in the current biomedicine landscape.
Prof. Dr. Alessandro F. Martins
Prof. Dr. Matt Kipper
Guest Editor
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Keywords
- drug delivery
- anisotropic gold nanoparticles
- scaffolds
- wound dressings
- wound healing
- biopolymers
- cancer therapies
- functionalization, antimicrobial coatings
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