Special Issue "Clinical and Forensic Toxicology: The Latest Updates"
Deadline for manuscript submissions: 22 March 2021.
Interests: toxicology; forensic toxicology; drugs of abuse; legal medicine; hepatotoxicity
Special Issues and Collections in MDPI journals
Within the field of analytical toxicology, there are two distinct disciplines involved in the testing of human biological matrices and non-biological specimens: clinical and forensic toxicology.
The difference between both specialties lies in the final use of the obtained results. In clinical toxicology, analytical results support clinical management, selection of an appropriate treatment, diagnosis, prognosis, and eventual disclosure of drug intoxication in the emergency room. In addition, drugs of abuse testing in maintenance treatments is also an area of special interest. In forensic toxicology, the obtained results have medico-legal implications related to eventual drug contribution to death or to possible impairment or to behavioral changes linked to a crime.
There are numerous areas of mutual interest between clinical and forensic toxicology. Indeed, most of the advances in the clinical setting come from investigation in forensic laboratories. Owing to those advances, the number of detectable pharmacological and psychoactive substances and/or metabolites and the number of conventional and non-conventional biological matrices to be investigated is continuously increasing. Furthermore, technological innovations in the field of sample pre-treatment and in the instrumental methodologies has improved levels of precision, accuracy, sensitivity, and specificity of quali-quantitative analyses in both disciplines.
The aim of this Special Issue is to collect original and review articles to provide the latest updates in the field of clinical and forensic toxicology.
Suggested topics include, but are not limited to:
- Determination of cannabinoids in biological matrices for clinical (medical cannabis) and forensic (recreational cannabis) purposes
- Development and validation of analytical methods for the identification and quantification of New Psychoactive Substances (NPS) in conventional and non-conventional biological matrices.
- Studies and updated reviews on drugs of abuse-related toxicity, acute intoxications, and fatalities.
- Metabolic pathways of new synthetic opioids, their potency, and studies of incubation with human hepatocytes to simulate in vivo metabolism.
Prof. Dr. Francesco P. Busardó
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Clinical toxicology
- Forensic toxicology
- Drugs of abuse
- Acute intoxications
- New Psychoactive Substances (NPS)
- Liquid chromatography-high resolution mass spectrometry (LC-HRMS/MS)
- Liquid chromatography-tandem mass spectrometry (LC-MS/MS)
- Gas chromatography-tandem mass spectrometry (GC-MS) and Gas chromatography-tandem mass spectrometry (GC-MS/MS)
- NPS-related toxicity