Bioprospecting, Drug Repositioning and Novel Therapeutic Strategies Against Protozoan Infections: From Mechanisms to Translational Applications
A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Natural Products".
Deadline for manuscript submissions: 30 November 2026 | Viewed by 45
Special Issue Editors
2. Laboratory of Biochemistry and Animal Toxins, Federal University of Uberlândia, Uberlândia 38405318, MG, Brazil
Interests: animal venoms; bioprospecting; biotechnological tools; snake venom; alternative treatments; drug discovery; natural products
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Protozoan infections remain a major global health challenge, particularly in neglected and congenital diseases such as toxoplasmosis, where current therapeutic options are limited and often associated with toxicity and variable efficacy. In this context, the identification of novel bioactive compounds—either through bioprospecting of natural products, synthetic approaches, or drug repositioning strategies—represents a promising and timely research direction.
This Special Issue aims to gather high-quality original research articles and reviews focusing on the following:
- Discovery of novel anti-protozoan compounds from natural, synthetic, or hybrid sources;
- Drug repurposing and repositioning strategies against protozoan parasites;
- Mechanisms of action, including host–parasite interactions and cellular/molecular pathways;
- In vitro and in vivo experimental models for drug screening and validation;
- Translational perspectives, including safety, efficacy, pharmacokinetics, and therapeutic applications;
- Studies addressing congenital and neglected parasitic diseases.
Dr. Samuel Teixeira
Dr. Bellisa Freitas Barbosa
Guest Editors
Manuscript Submission Information
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Keywords
- bioprospecting
- drug repositioning
- protozoan infections
- mechanism
- translational perspectives
- congenital and neglected parasitic diseases
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