Pharmacokinetics and Pharmacodynamics for Co-Administration of Drugs
A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Pharmacology".
Deadline for manuscript submissions: closed (31 March 2023) | Viewed by 318
Special Issue Editors
Interests: pharmacokinetics; drug–drug interaction
Interests: clinical pharmacology; model-informed drug development; model-informed dose optimization; AI-driven drug development
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue is entitled “Pharmacokinetics (PK) and Pharmacodynamics (PD) for Co-Administration of Drugs”. Patients are often given two or more drugs at the same time to modulate the multiple pathophysiological mechanisms of a disease, to treat two or more coexisting diseases or symptoms, to induce a synergistic effect, or to counteract the side effects or resistance of drugs. Pharmacokinetic or pharmacodynamic drug interactions among co-administered drugs are a source of variability in clinical drug response. The Special Issue aims to cover the following topics: (a) clinical/preclinical PK/PD studies to investigate drug interactions among co-administered drugs; (b) PK/PD modeling, in silico prediction or machine learning applications to predict drug interactions; (c) drug–drug–gene interactions, polymorphisms of enzymes, transporters, and receptors involved in the various reactions of drug interactions; (d) PK/PD of co-administered herbal/biologic products; (e) drug interactions on side effects of drugs; (f) overview of the current trends/hurdles of PK/PD studies or guidelines for combination drug therapy.
Dr. Namyi Gu
Dr. Kwang-Hee Shin
Guest Editors
Manuscript Submission Information
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Keywords
- co-administration
- drug interaction
- pharmacokinetics
- pharmacodynamics
- in silico simulation
- machine learning
- polymorphism
- biologic product
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