Potential Therapeutic Targets for the Treatment of Pathological Pain

Dear Colleagues,

As one of the most common reasons people seek medical care, pain is an issue of extreme relevance. Pathological pain, such as chronic inflammatory, neuropathic, and dysfunctional or nociplastic pain impairs the life quality of patients, leading to the development of anxiety, depression, labour capacity loss, and even distancing from family members and society. Often, the analgesic drugs used clinically present limited efficacy and cause various adverse effects, including analgesic tolerance, dependency, and abuse possibility, limiting their use. Thus, identifying potential therapeutic targets for treating pathological pain is highly relevant for developing more effective and safe analgesic drugs for adequate pain relief. This Special Issue is intended to investigate potential therapeutic targets for developing new analgesics, the signalling pathways involved in these processes, and the analgesic effect of synthetic drugs or natural products in pathological pain models.

We look forward to receiving your contributions.

Dr. Sara Marchesan De Oliveira
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.